Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Esta Tamanaha"'
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
A colorimetric detection method produces strong, quantifiable visible color changes in response to nucleic acid amplification for point-of-care, field, and at-home applications without the need for sophisticated laboratory instrumentation.
Externí odkaz:
https://doaj.org/article/4db01b273b2f4d13904b8df61a66c9db
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0259610 (2022)
The ongoing SARS-CoV-2 pandemic has necessitated a dramatic increase in our ability to conduct molecular diagnostic tests, as accurate detection of the virus is critical in preventing its spread. However, SARS-CoV-2 variants continue to emerge, with
Externí odkaz:
https://doaj.org/article/8d492ac4a5734d0388ef7e632d7c0a10
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Prokaryotic Argonautes (pAgo) are an increasingly well-studied class of guided endonucleases, and the underlying mechanisms by which pAgo generate nucleic acid guides in vivo remains an important topic of investigation. Recent insights into these mec
Externí odkaz:
https://doaj.org/article/907f655b17f547f480e1f1a805912cf1
Publikováno v:
PloS one. 17(3)
The ongoing SARS-CoV-2 pandemic has necessitated a dramatic increase in our ability to conduct molecular diagnostic tests, as accurate detection of the virus is critical in preventing its spread. However, SARS-CoV-2 variants continue to emerge, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618fde7d9052eaa995902fa89eea99fb
https://pubmed.ncbi.nlm.nih.gov/35324900
https://pubmed.ncbi.nlm.nih.gov/35324900
Autor:
Ivan R. Corrêa, Eileen T. Dimalanta, Matthew A. Campbell, Katherine Marks, Heidi E. Church, James C. Samuelson, Louise Williams, V.K. Chaithanya Ponnaluri, Sriharsa Pradhan, Brittany S. Sexton, Thomas C. Evans, Zhiyi Sun, Theodore B. Davis, Mala Samaranayake, Shengxi Guan, Bradley W. Langhorst, Romualdas Vaisvila, Esta Tamanaha, Lana Saleh, Nan Dai
Publikováno v:
Genome Res
Bisulfite sequencing detects 5mC and 5hmC at single-base resolution. However, bisulfite treatment damages DNA, which results in fragmentation, DNA loss, and biased sequencing data. To overcome these problems, enzymatic methyl-seq (EM-seq) was develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e6707ce82b4535258858bae90c5c9a
https://europepmc.org/articles/PMC8256858/
https://europepmc.org/articles/PMC8256858/
Autor:
Matthew A. Campbell, Katherine Marks, Sriharsa Pradhan, Eileen T. Dimalanta, Heidi E. Church, James C. Samuelson, Thomas C. Evans, Nan Dai, Louise Williams, Bradley W. Langhorst, Zhiyi Sun, V.K. Chaithanya Ponnaluri, Mala Samaranayake, Lana Saleh, Esta Tamanaha, Ivan R. Corrêa, Romualdas Vaisvila, Shengxi Guan, Brittany S. Sexton, Theodore B. Davis
Bisulfite sequencing is widely used to detect 5mC and 5hmC at single base resolution. It is the most accepted method for detecting these cytosine modifications, but it does have significant drawbacks. DNA is frequently damaged resulting in fragmentat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d620f8f2148837512b1f04713492f9e5
https://doi.org/10.1101/2019.12.20.884692
https://doi.org/10.1101/2019.12.20.884692
Publikováno v:
Journal of the American Chemical Society. 138:9345-9348
The ten-eleven translocation (TET) proteins catalyze oxidation of 5-methylcytosine ((5m)C) residues in nucleic acids to 5-hydroxymethylcytosine ((5hm)C), 5-formylcytosine ((5f)C), and 5-carboxycytosine ((5ca)C). These nucleotide bases have been impli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce0579b3a014fa6c5d0f95b67fdab12
https://doi.org/10.1021/jacs.6b03243
https://doi.org/10.1021/jacs.6b03243
Autor:
Zhiyi Sun, Lana Saleh, Shengxi Guan, Jurate Bitinaite, Richard J. Roberts, Ivan R. Corrêa, Alexey Fomenkov, Romualdas Vaisvila, Christopher J. Noren, Esta Tamanaha, Xiaodong Cheng, Yu Zheng, Nan Dai, June E. Pais
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(14)
Modified DNA bases in mammalian genomes, such as 5-methylcytosine ( 5m C) and its oxidized forms, are implicated in important epigenetic regulation processes. In human or mouse, successive enzymatic conversion of 5m C to its oxidized forms is carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2664560765a1337e5857ef14b7c6ef
https://pubmed.ncbi.nlm.nih.gov/25831492
https://pubmed.ncbi.nlm.nih.gov/25831492
Publikováno v:
The FASEB Journal. 28
Reversible methylation of DNA is a powerful and ubiquitous mechanism for dynamic control of gene expression. The recent discovery that deoxy-5-methylcytosine (d5mC) in mammalian DNA can be iteratively oxidized by ten eleven translocation (TET) protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bf3b6c4192330850e1f84f1502fcaf3
https://doi.org/10.1096/fasebj.28.1_supplement.768.16
https://doi.org/10.1096/fasebj.28.1_supplement.768.16
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2e47a76fd7c0e06acb5d335a630128c
https://doi.org/10.1096/fasebj.25.1_supplement.195.1
https://doi.org/10.1096/fasebj.25.1_supplement.195.1