Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Essie Komla"'
Autor:
Stanley M. Cheatham, Karan H. Muchhala, Eda Koseli, Joanna C. Jacob, Essie Komla, S. Stevens Negus, Hamid I. Akbarali
Publikováno v:
Frontiers in Pain Research, Vol 2 (2021)
Opioids and non-steroidal anti-inflammatory drugs (NSAIDs) are excellent analgesics, but recent clinical evidence suggests that these drugs might worsen disease severity in Crohn's disease patients, limiting their clinical utility for treating Inflam
Externí odkaz:
https://doaj.org/article/184c370b9bd846b38ef4566f1158225e
Autor:
Bhupal Ban, Rodell C. Barrientos, Therese Oertel, Essie Komla, Connor Whalen, Megan Sopko, Yingjian You, Partha Banerjee, Agnieszka Sulima, Arthur E. Jacobson, Kenner C. Rice, Gary R. Matyas, Vidadi Yusibov
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
The prevalence and societal impact of opioid use disorder (OUD) is an acknowledged public health crisis that is further aggravated by the current pandemic. One of the devastating consequences of OUD is opioid overdose deaths. While multiple medicatio
Externí odkaz:
https://doaj.org/article/a57dc3421a724889a100c3b2663a617c
Autor:
Essie Komla, Oscar B. Torres, Rashmi Jalah, Agnieszka Sulima, Zoltan Beck, Carl R. Alving, Arthur E. Jacobson, Kenner C. Rice, Gary R. Matyas
Publikováno v:
Vaccines, Vol 9, Iss 6, p 573 (2021)
Opioid use disorder (OUD) is a serious health problem that has dramatically increased over the last decade. Although current therapies for the management of OUD can be effective, they have limitations. The complementary strategy to combat the opioid
Externí odkaz:
https://doaj.org/article/47bc77d6842540b0ba881eac76c62dd9
Autor:
Agnieszka Sulima, Rodell C. Barrientos, Eric W Bow, Kenner C. Rice, Essie Komla, Oscar B. Torres, Gary R. Matyas, Zoltan Beck, Arthur E. Jacobson, Connor Whalen
Publikováno v:
Bioconjugate Chemistry
Opioid use disorders and fatal overdose due to consumption of fentanyl-laced heroin remain a major public health menace in the United States. Vaccination may serve as a promising potential remedy to combat accidental overdose and to mitigate the abus
Autor:
Vidadi Yusibov, Therese Oertel, Kenner C. Rice, Agnieszka Sulima, Megan Sopko, Essie Komla, Partha Banerjee, Gary R. Matyas, Bhupal Ban, Yingjian You, Rodell C. Barrientos, Connor Whalen, Arthur E. Jacobson
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The prevalence and societal impact of opioid use disorder (OUD) is an acknowledged public health crisis that is further aggravated by the current pandemic. One of the devastating consequences of OUD is opioid overdose deaths. While multiple medicatio
Autor:
D. Matthew Walentiny, Hamid I. Akbarali, Essie Komla, Justin L. Poklis, Patrick M. Beardsley, Lea T. Moisa, Mohammed A. Mustafa
Publikováno v:
Neuropharmacology
Background Antagonism of peripheral opioid receptors by methylnaltrexone (MNTX) was recently proposed as a potential mechanism to attenuate the development of opioid analgesic tolerance based on experiments conducted in mice. However, reports indicat
Autor:
William L. Dewey, Hamid I. Akbarali, Huiqun Wang, David Stevens, Samuel Obeng, Dana E. Selley, Essie Komla, Yi Zheng, Yan Zhang
Publikováno v:
ACS Chemical Neuroscience. 9:3028-3037
Two 6β- N-heterocyclic naltrexamine derivatives, NAP and NMP, have been identified as peripherally selective mu opioid receptor (MOR) antagonists. To further enhance the peripheral selectivity of both compounds, the 17-amino group and the nitrogen a
Autor:
Zoltan Beck, Rashmi Jalah, Oscar B. Torres, Essie Komla, Agnieszka Sulima, Kenner C. Rice, Arthur E. Jacobson, Gary R. Matyas, Carl R. Alving
Publikováno v:
Vaccines
Volume 9
Issue 6
Vaccines, Vol 9, Iss 573, p 573 (2021)
Volume 9
Issue 6
Vaccines, Vol 9, Iss 573, p 573 (2021)
Opioid use disorder (OUD) is a serious health problem that has dramatically increased over the last decade. Although current therapies for the management of OUD can be effective, they have limitations. The complementary strategy to combat the opioid
Publikováno v:
J Pharmacol Exp Ther
Opioids are highly effective analgesics, however, their therapeutic use is limited by adverse effects that include respiratory depression, dependence, and tolerance. Inflammation has been implicated as a significant driver for the development of tole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5a33a74327b37a9edb899d0179185e
https://europepmc.org/articles/PMC6806632/
https://europepmc.org/articles/PMC6806632/
Publikováno v:
The FASEB Journal. 32