Zobrazeno 1 - 10
of 10 841
pro vyhledávání: '"Essential Thrombocythemia"'
Publikováno v:
Radiology and Oncology, Vol 58, Iss 4, Pp 565-572 (2024)
JAK2 V617F (JAK2) mutation is associated with clonal hemopoiesis in myeloproliferative neoplasms as well as with faster progression of cardiovascular diseases. Little is known about the relationship between allele burden and the degree of atheroscler
Externí odkaz:
https://doaj.org/article/537a7cc588084dd9ad54dadc72bdeca8
Publikováno v:
Bulletin of the National Research Centre, Vol 48, Iss 1, Pp 1-8 (2024)
Abstract Background Patients with essential thrombocythemia (ET) can develop systemic thrombotic and hemorrhagic vascular complications due to increased and dysfunctional platelets. Case presentation We encountered a 49-year-old Japanese woman with a
Externí odkaz:
https://doaj.org/article/98640108da544eb0847877f461bf2c40
Autor:
Ravi Patel, Nathan DeRon Jr.
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by uninhibited platelet production. It can present with vasomotor symptoms, and less commonly, severe thrombotic events such as myocardial infarction. S
Externí odkaz:
https://doaj.org/article/2c4412b902fb4436a868b58af711580c
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-5 (2024)
Abstract Essential thrombocythemia (ET) is a myeloproliferative malignancy caused by the excessive proliferation of megakaryocytes in the bone marrow, resulting in the overproduction of peripheral platelets. ET can lead to thrombotic events, such as
Externí odkaz:
https://doaj.org/article/0a963b03d0dd45c083f909f6f13321d8
Autor:
Shotaro Tabata, Yusuke Yamashita, Yoko Inai, Shuhei Morita, Hideki Kosako, Tomoyuki Takagi, Kotaro Shide, Shino Manabe, Taka-aki Matsuoka, Kazuya Shimoda, Takashi Sonoki, Yoshito Ihara, Shinobu Tamura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract C-Mannosyl tryptophan (CMW), a unique glycosylated amino acid, is considered to be produced by degradation of C-mannosylated proteins in living organism. Although protein C-mannosylation is involved in the folding and secretion of substrate
Externí odkaz:
https://doaj.org/article/cf7255d948d5456fba60fbd1450bf30d
Publikováno v:
JAAD Case Reports, Vol 52, Iss , Pp 46-48 (2024)
Externí odkaz:
https://doaj.org/article/41d0363137fc48688b399b27b3a21a5a
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8407-8423 (2024)
Myeloproliferative neoplasms (MPNs), encompassing disorders like polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), are characterized by clonal hematopoiesis without the Philadelphia chromosome. The JAK2 V617F mu
Externí odkaz:
https://doaj.org/article/a49f87b12aaa447683216f7cda8c9265
Autor:
Chie Asou, Tomoyuki Sakamoto, Kodai Suzuki, Itoko Okuda, Atsushi Osaki, Ryohei Abe, Yoshihiro Ito, Emi Kakegawa, Yoshitaka Miyakawa, Yasuhito Terui, Yuichi Nakamura
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-5 (2024)
Abstract Background Blast transformation is a rare but well-recognized event in Philadelphia-negative myeloproliferative neoplasms associated with a poor prognosis. Secondary acute myeloid leukemias evolving from myeloproliferative neoplasms are char
Externí odkaz:
https://doaj.org/article/20ad831a1d844d00a58a9546ec999cd6
Autor:
Christopher Puli'uvea, Tracey Immanuel, Taryn N. Green, Peter Tsai, Peter R. Shepherd, Maggie L. Kalev-Zylinska
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Objectives: This study aimed to compile bioinformatic and experimental information for JAK2 missense variants previously reported in myeloproliferative neoplasms (MPN) and determine if germline JAK2-I724T, recently found to be common in New Zealand P
Externí odkaz:
https://doaj.org/article/ce5b4c33076141b4ba8b6008985068fb
Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia
Autor:
Veronika Dill, Kilian Kirmes, Jiaying Han, Melissa Klug, Marc Rosenbaum, Giacomo Viggiani, Moritz von Scheidt, Markus List, Peter Herhaus, Jürgen Ruland, Florian Bassermann, Karl-Ludwig Laugwitz, Katharina S. Götze, Philipp J. Jost, Stefanie Jilg, Conor J. Bloxham, Philip W.J. Raake, Isabell Bernlochner, Dario Bongiovanni
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
Thromboembolic events are common in patients with essential thrombocythemia (ET). However, the pathophysiological mechanisms underlying the increased thrombotic risk remain to be determined. Here, we perform the first phenotypical characterization of
Externí odkaz:
https://doaj.org/article/6b03b9ff955e40ae9ff5ee319c518d34