Výsledky vyhledávání - "Esra Bulut Atalay"

Investigation of Energy Metabolism in The Different Tissues of Colon Cancer Xenograft Models Based on The TCA and Cori Cycles and Glycolysis

Autor: Esra BULUT ATALAY, Hülya AYAR KAYALI

Publikováno v: Uluslararası Muhendislik Arastirma ve Gelistirme Dergisi. 15:117-124

The metabolism is reprogrammed in cancer cells to meet the requirement of their malignant properties. Some specific metabolites can contribute to the malignant transformation in different cancer types. This study aimed to determine the level of gluco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::940b90e5a24fa943ca4939365ca6080d
https://doi.org/10.29137/umagd.1142303

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Wild-type IDH1 Knockout Leads to G0/G1 Arrest, Impairs Cancer Cell Proliferation, Altering Glycolysis, and the TCA Cycle in Colon Cancer

Autor: Esra Bulut Atalay, Serif Senturk, Hulya Ayar Kayali

Publikováno v: Biochemical Genetics.

The isocitrate dehydrogenase (IDH), which participates in the TCA cycle, is an important key enzyme in regulating cell metabolism. The effect of the metabolic IDH enzyme on cancer pathogenesis has recently been shown in different types of cancer. How

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3592dea6521a027bf896e9bc5c8f861f
https://doi.org/10.1007/s10528-022-10325-1

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The elevated D-2-hydroxyglutarate level found as a characteristic metabolic change of colon cancer in both in vitro and in vivo models

Autor: Esra Bulut Atalay, Hulya Ayar Kayali

Publikováno v: Biochemical and biophysical research communications. 627

The D-2-hydroxyglutarate (D-2-HG), whose normal cellular concentration is low, can be accumulated 10-100 times natural levels in some cancer types and participates in the carcinogenesis process. D-2-HG is produced by different pathways specific to ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a1c35824fd991d3281d5064325d45f
https://pubmed.ncbi.nlm.nih.gov/36049357

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The Role of Kinase Inhibitors in Cancer Therapies

Autor: Yonca Gungor, Duygu Erdogan, Seminay Guler, Hulya Ayar Kayali, Gizem Kursunluoglu, Esra Bulut Atalay, Elcin Cagatay

Protein kinases are enzymes that transfer a phosphate group to the threonine, serine, or tyrosine residues of the target protein, regulating its activity. The activity of these enzymes are very important and strictly regulated in the cell as they pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64d3f0c014d98c97beca4dc214a8488
https://mts.intechopen.com/articles/show/title/the-role-of-kinase-inhibitors-in-cancer-therapies

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Synthesis And Characterization Of Thiosemicarbazone-Functionalized Organoruthenium (Ii)-Arene Complexes: Investigation Of Antitumor Characteristics In Colorectal Cancer Cell Lines

Autor: Duygu Erdogan, Bilge Pakyapan, Elif Subasi, Hulya Ayar Kayali, Esra Bulut Atalay, Betül Şen

In the current study, organoruthenium(II)-arene complexes (I-IV) have been prepared by the reaction of ({(eta(6)-pcym)RuCl}(2)(mu-Cl)(2)] with new thiosemicarbazones (TSC1-4).The isolate was analyzed using elemental analysis, FT-IR, H-1 and C-13 NMR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151670c54c69c9b7c984b4ea5f6c86ff
https://aperta.ulakbim.gov.tr/record/9615

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