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Developing aptamers by cell-based SELEX

Autor: Catuogno S., Esposito C.L., de Franciscis V.

Publikováno v: Methods in molecular biology (Clifton N.J.) 1380 (2016): 33–46. doi:10.1007/978-1-4939-3197-2_3
info:cnr-pdr/source/autori:Catuogno S.; Esposito C.L.; de Franciscis V./titolo:Developing aptamers by cell-based SELEX/doi:10.1007%2F978-1-4939-3197-2_3/rivista:Methods in molecular biology (Clifton N.J.)/anno:2016/pagina_da:33/pagina_a:46/intervallo_pagine:33–46/volume:1380

The reliable targeting of cell surface disease-associated proteins is a major challenge in chemical biology and molecular medicine. In this regard, aptamers represent a very attractive and innovative class of ligand molecules. Aptamers are generated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::ec42de91af535f2bdd5c94feb256f36b
https://publications.cnr.it/doc/355286

1998P - The discovery of RNA-aptamers that selectively bind and inhibit glioblastoma stem cells by targeting EphA2

Autor: Affinito, A. ¹, Quintavalle, C. ¹, Esposito, C.L. ², Roscigno, G. ³, Vilardo, C. ³, Nuzzo, S. ⁴, Ricci Vitiani, L. ⁵, De Luca, G. ⁵, Minic, Z. ⁶, Giannetti, S. ⁷, Pallini, R. ⁸, Berezovski, M.V. ⁶, Kichkailo, A.S. ⁹, Lapin, I.N. ¹⁰, De Franciscis, V. ², Condorelli, G. ¹¹

Publikováno v: In Annals of Oncology October 2019 30 Supplement 5:v802-v802

Aptamers as innovative diagnostic and therapeutic agents in the central nervous system

Autor: de Franciscis V., Esposito C.L., Catuogno S., Cellai L., Cerchia L.

Publikováno v: 8 (2009): 393–401.
info:cnr-pdr/source/autori:de Franciscis V., Esposito C.L., Catuogno S., Cellai L., Cerchia L./titolo:Aptamers as innovative diagnostic and therapeutic agents in the central nervous system./doi:/rivista:/anno:2009/pagina_da:393/pagina_a:401/intervallo_pagine:393–401/volume:8

Aptamers are short non-naturally occurring single stranded DNA or RNA able to bind tightly, due to their specific three-dimensional shapes, to a multitude of targets ranging from small chemical compounds to cells and tissues. Since their first discov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::8215d135d0fa9bca9d1dd0bd9209dd64
https://publications.cnr.it/doc/19854