Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Espiritu SMG"'
Autor:
Christopher M. Lalansingh, Anthony C. Nichols, Szyca L, Paul C. Boutros, Cindy Q. Yao, Kathleen E. Houlahan, Takafumi N. Yamaguchi, John W. Barrett, Stephenie D. Prokopec, Lawrence E. Heisler, Espiritu Smg, Ren X. Sun, Morgan Black, Constance H. Li
The detection of somatic single nucleotide variants (SNVs) is critical in both research and clinical applications. Studies of human cancer typically use matched normal (reference) samples from a distant tissue to increase SNV prediction accuracy. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f75e53c57262f2009fc5a3c6664449
https://doi.org/10.1101/383703
https://doi.org/10.1101/383703
Autor:
Salcedo A; Department of Human Genetics, University of California, Los Angeles, CA, USA. ASalcedo@mednet.ucla.edu.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA. ASalcedo@mednet.ucla.edu.; Institute for Precision Health, University of California, Los Angeles, CA, USA. ASalcedo@mednet.ucla.edu.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. ASalcedo@mednet.ucla.edu.; Ontario Institute for Cancer Research, Toronto, Ontario, Canada. ASalcedo@mednet.ucla.edu., Tarabichi M; The Francis Crick Institute, London, UK. maxime.tarabichi@ulb.be.; Wellcome Sanger Institute, Hinxton, UK. maxime.tarabichi@ulb.be.; Institute for Interdisciplinary Research, Université Libre de Bruxelles, Brussels, Belgium. maxime.tarabichi@ulb.be., Buchanan A; Oregon Health and Sciences University, Portland, OR, USA., Espiritu SMG; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Zhang H; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Zhu K; Department of Systems Biology, Columbia University, New York, NY, USA.; Center for Cancer Systems Therapeutics, Columbia University, New York, NY, USA.; Department of Electrical Engineering, Columbia University, New York, NY, USA., Ou Yang TH; Department of Systems Biology, Columbia University, New York, NY, USA.; Center for Cancer Systems Therapeutics, Columbia University, New York, NY, USA.; Department of Electrical Engineering, Columbia University, New York, NY, USA., Leshchiner I; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Anastassiou D; Department of Systems Biology, Columbia University, New York, NY, USA.; Center for Cancer Systems Therapeutics, Columbia University, New York, NY, USA.; Department of Electrical Engineering, Columbia University, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA., Guan Y; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Electronic Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA., Jang GH; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Mootor MFE; Department of Human Genetics, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA.; Institute for Precision Health, University of California, Los Angeles, CA, USA., Haase K; The Francis Crick Institute, London, UK., Deshwar AG; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada., Zou W; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Umar I; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Dentro S; The Francis Crick Institute, London, UK.; Wellcome Sanger Institute, Hinxton, UK., Wintersinger JA; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada., Chiotti K; Oregon Health and Sciences University, Portland, OR, USA., Demeulemeester J; The Francis Crick Institute, London, UK.; VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium., Jolly C; The Francis Crick Institute, London, UK., Sycza L; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Ko M; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Wedge DC; Big Data Institute, University of Oxford, Oxford, UK.; Manchester Cancer Research Center, University of Manchester, Manchester, UK., Morris QD; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.; Vector Institute, Toronto, Ontario, Canada.; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ellrott K; Oregon Health and Sciences University, Portland, OR, USA. ellrott@ohsu.edu., Van Loo P; The Francis Crick Institute, London, UK. pvanloo@mdanderson.org.; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. pvanloo@mdanderson.org.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. pvanloo@mdanderson.org., Boutros PC; Department of Human Genetics, University of California, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Institute for Precision Health, University of California, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. pboutros@mednet.ucla.edu.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. pboutros@mednet.ucla.edu.; Department of Urology, University of California, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Broad Stem Cell Research Center, University of California, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; California NanoSystems Institute, University of California, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.
Publikováno v:
Nature biotechnology [Nat Biotechnol] 2024 Jun 11. Date of Electronic Publication: 2024 Jun 11.
Autor:
Liu LY; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 1L7, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2C1, Canada.; Vector Institute for Artificial Intelligence, Toronto, ON, M5G 1M1, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, CA, 90024, USA.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Bhandari V; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 1L7, Canada., Salcedo A; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 1L7, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, CA, 90024, USA.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Ontario Institute for Cancer Research, Toronto, ON, M5G 0A3, Canada., Espiritu SMG; Ontario Institute for Cancer Research, Toronto, ON, M5G 0A3, Canada., Morris QD; Vector Institute for Artificial Intelligence, Toronto, ON, M5G 1M1, Canada.; Department of Computer Science, University of Toronto, Toronto, ON, M5T 3A1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada.; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Kislinger T; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 1L7, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2C1, Canada., Boutros PC; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 1L7, Canada. pboutros@mednet.ucla.edu.; Vector Institute for Artificial Intelligence, Toronto, ON, M5G 1M1, Canada. pboutros@mednet.ucla.edu.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA. pboutros@mednet.ucla.edu.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, CA, 90024, USA. pboutros@mednet.ucla.edu.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, 90095, USA. pboutros@mednet.ucla.edu.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A8, Canada. pboutros@mednet.ucla.edu.; Department of Urology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. pboutros@mednet.ucla.edu.
Publikováno v:
Nature communications [Nat Commun] 2020 Dec 07; Vol. 11 (1), pp. 6247. Date of Electronic Publication: 2020 Dec 07.
Autor:
Zhou S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Hawley JR; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Soares F; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Grillo G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Teng M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Madani Tonekaboni SA; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Hua JT; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Kron KJ; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Mazrooei P; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Ahmed M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Arlidge C; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Yun HY; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Livingstone J; Ontario Institute for Cancer Research, Toronto, ON, Canada., Huang V; Ontario Institute for Cancer Research, Toronto, ON, Canada., Yamaguchi TN; Ontario Institute for Cancer Research, Toronto, ON, Canada., Espiritu SMG; Ontario Institute for Cancer Research, Toronto, ON, Canada., Zhu Y; Division of Oncogenomics, Oncode Institute, the Netherlands Cancer Institute, Amsterdam, The Netherlands., Severson TM; Division of Oncogenomics, Oncode Institute, the Netherlands Cancer Institute, Amsterdam, The Netherlands., Murison A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Cameron S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Zwart W; Division of Oncogenomics, Oncode Institute, the Netherlands Cancer Institute, Amsterdam, The Netherlands.; Laboratory of Chemical Biology and Institute for Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands., van der Kwast T; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Pugh TJ; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Ontario Institute for Cancer Research, Toronto, ON, Canada., Fraser M; Ontario Institute for Cancer Research, Toronto, ON, Canada., Boutros PC; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Ontario Institute for Cancer Research, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, CA, Canada.; Department of Human Genetics, University of California, Los Angeles, CA, USA.; Department of Urology, University of California, Los Angeles, CA, USA.; Institute for Precision Health, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA., Bristow RG; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.; CRUK Manchester Institute and Manchester Cancer Research Centre, Manchester, UK.; Division of Cancer Sciences, Faculty of Biology, Health and Medicine, University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester, UK., He HH; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Lupien M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. mlupien@uhnresearch.ca.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. mlupien@uhnresearch.ca.; Ontario Institute for Cancer Research, Toronto, ON, Canada. mlupien@uhnresearch.ca.
Publikováno v:
Nature communications [Nat Commun] 2020 Jan 23; Vol. 11 (1), pp. 441. Date of Electronic Publication: 2020 Jan 23.
Autor:
Salcedo A; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Tarabichi M; The Francis Crick Institute, London, UK.; Wellcome Trust Sanger Institute, Hinxton, UK., Espiritu SMG; Ontario Institute for Cancer Research, Toronto, Canada., Deshwar AG; The Edward S. Rogers Senior Department of Electrical & Computer Engineering, Toronto, Canada., David M; Ontario Institute for Cancer Research, Toronto, Canada., Wilson NM; Ontario Institute for Cancer Research, Toronto, Canada., Dentro S; The Francis Crick Institute, London, UK.; Wellcome Trust Sanger Institute, Hinxton, UK., Wintersinger JA; Donnelly Centre, University of Toronto, Toronto, Canada., Liu LY; Ontario Institute for Cancer Research, Toronto, Canada., Ko M; Ontario Institute for Cancer Research, Toronto, Canada., Sivanandan S; Ontario Institute for Cancer Research, Toronto, Canada., Zhang H; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Zhu K; Department of Systems Biology, Columbia University, New York, NY, USA.; Center for Cancer Systems Therapeutics, Columbia University, New York, NY, USA.; Department of Electrical Engineering, Columbia University, New York, NY, USA., Ou Yang TH; Department of Systems Biology, Columbia University, New York, NY, USA.; Center for Cancer Systems Therapeutics, Columbia University, New York, NY, USA.; Department of Electrical Engineering, Columbia University, New York, NY, USA., Chilton JM; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA., Buchanan A; Oregon Health & Sciences University, Portland, OR, USA., Lalansingh CM; Ontario Institute for Cancer Research, Toronto, Canada., P'ng C; Ontario Institute for Cancer Research, Toronto, Canada., Anghel CV; Ontario Institute for Cancer Research, Toronto, Canada., Umar I; Ontario Institute for Cancer Research, Toronto, Canada., Lo B; Ontario Institute for Cancer Research, Toronto, Canada., Zou W; Ontario Institute for Cancer Research, Toronto, Canada., Simpson JT; Ontario Institute for Cancer Research, Toronto, Canada., Stuart JM; Department of Biomolecular Engineering, Center for Biomolecular Sciences and Engineering, University of California, Santa Cruz, Santa Cruz, CA, USA., Anastassiou D; Department of Systems Biology, Columbia University, New York, NY, USA.; Center for Cancer Systems Therapeutics, Columbia University, New York, NY, USA.; Department of Electrical Engineering, Columbia University, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, USA., Guan Y; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Electronic Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA., Ewing AD; Mater Research Institute, University of Queensland, Woolloongabba, Queensland, Australia., Ellrott K; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA.; Oregon Health & Sciences University, Portland, OR, USA., Wedge DC; Big Data Institute, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford, UK., Morris Q; Ontario Institute for Cancer Research, Toronto, Canada.; Donnelly Centre, University of Toronto, Toronto, Canada.; Computational and Systems Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Vector Institute for Artificial Intelligence, Toronto, Canada., Van Loo P; The Francis Crick Institute, London, UK.; Department of Human Genetics, University of Leuven, Leuven, Belgium., Boutros PC; Department of Medical Biophysics, University of Toronto, Toronto, Canada. pboutros@mednet.ucla.edu.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada. pboutros@mednet.ucla.edu.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.
Publikováno v:
Nature biotechnology [Nat Biotechnol] 2020 Jan; Vol. 38 (1), pp. 97-107. Date of Electronic Publication: 2020 Jan 09.
Autor:
Houlahan KE; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Vector Institute, Toronto, Ontario, Canada., Shiah YJ; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Gusev A; Division of Population Sciences, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Yuan J; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, USA., Ahmed M; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Shetty A; Division of Population Sciences, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.; University of Cambridge, Cambridge, UK., Ramanand SG; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, USA., Yao CQ; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Bell C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., O'Connor E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Huang V; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Fraser M; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Heisler LE; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Livingstone J; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Yamaguchi TN; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Rouette A; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Foucal A; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Espiritu SMG; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Sinha A; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Sam M; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Timms L; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Johns J; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Wong A; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Murison A; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Orain M; Department of Pathology, Centre de recheche du CHU de Québec-Université Laval, Québec City, Québec, Canada., Picard V; Division of Urology, Centre de recheche du CHU de Québec-Université Laval, Québec City, Québec, Canada., Hovington H; Division of Urology, Centre de recheche du CHU de Québec-Université Laval, Québec City, Québec, Canada., Bergeron A; Division of Urology, Centre de recheche du CHU de Québec-Université Laval, Québec City, Québec, Canada., Lacombe L; Division of Urology, Centre de recheche du CHU de Québec-Université Laval, Québec City, Québec, Canada., Lupien M; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Fradet Y; Division of Urology, Centre de recheche du CHU de Québec-Université Laval, Québec City, Québec, Canada., Têtu B; Department of Pathology, Centre de recheche du CHU de Québec-Université Laval, Québec City, Québec, Canada., McPherson JD; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Pasaniuc B; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Kislinger T; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Chua MLK; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore., Pomerantz MM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., van der Kwast T; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada., Freedman ML; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; The Eli and Edythe L. Broad Institute, Cambridge, MA, USA.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Mani RS; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, USA., He HH; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Bristow RG; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. robert.bristow@manchester.ac.uk.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. robert.bristow@manchester.ac.uk.; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada. robert.bristow@manchester.ac.uk.; Division of Cancer Sciences, Faculty of Biology, Health and Medicine, University of Manchester, Manchester, UK. robert.bristow@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester, UK. robert.bristow@manchester.ac.uk.; Cancer Research UK Manchester Institute, Manchester, UK. robert.bristow@manchester.ac.uk.; Manchester Cancer Research Centre, Manchester, UK. robert.bristow@manchester.ac.uk., Boutros PC; Ontario Institute for Cancer Research, Toronto, Ontario, Canada. pboutros@mednet.ucla.edu.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. pboutros@mednet.ucla.edu.; Vector Institute, Toronto, Ontario, Canada. pboutros@mednet.ucla.edu.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. pboutros@mednet.ucla.edu.; Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.
Publikováno v:
Nature medicine [Nat Med] 2019 Oct; Vol. 25 (10), pp. 1615-1626. Date of Electronic Publication: 2019 Oct 07.
Autor:
Bhandari V; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Hoey C; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Liu LY; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Lalonde E; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Ray J; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Livingstone J; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Lesurf R; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Shiah YJ; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Vujcic T; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Huang X; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Espiritu SMG; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Heisler LE; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Yousif F; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Huang V; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Yamaguchi TN; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Yao CQ; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Sabelnykova VY; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Fraser M; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Chua MLK; Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore.; Duke-NUS Graduate Medical School, Singapore, Singapore., van der Kwast T; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada., Liu SK; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada., Boutros PC; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. pboutros@mednet.ucla.edu.; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada. pboutros@mednet.ucla.edu.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. pboutros@mednet.ucla.edu.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, USA. pboutros@mednet.ucla.edu., Bristow RG; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. robert.bristow@manchester.ac.uk.; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada. robert.bristow@manchester.ac.uk.; Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada. robert.bristow@manchester.ac.uk.; Division of Cancer Sciences, Faculty of Biology, Health and Medicine, University of Manchester, Manchester, UK. robert.bristow@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester, UK. robert.bristow@manchester.ac.uk.; CRUK Manchester Institute and Manchester Cancer Research Centre, Manchester, UK. robert.bristow@manchester.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2019 Feb; Vol. 51 (2), pp. 308-318. Date of Electronic Publication: 2019 Jan 14.
Autor:
Lee AY; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Ewing AD; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA, USA.; Mater Research Institute, University of Queensland, Woolloongabba, QLD, Australia., Ellrott K; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA, USA.; Computational Biology Program, Oregon Health & Science University, Portland, OR, USA., Hu Y; Sage Bionetworks, Seattle, WA, USA., Houlahan KE; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Bare JC; Sage Bionetworks, Seattle, WA, USA., Espiritu SMG; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Huang V; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Dang K; Sage Bionetworks, Seattle, WA, USA., Chong Z; Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA.; Informatics Institute, University of Alabama at Birmingham, Birmingham, AL, USA., Caloian C; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Yamaguchi TN; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Kellen MR; Sage Bionetworks, Seattle, WA, USA., Chen K; Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Norman TC; Sage Bionetworks, Seattle, WA, USA., Friend SH; Sage Bionetworks, Seattle, WA, USA., Guinney J; Sage Bionetworks, Seattle, WA, USA., Stolovitzky G; IBM Computational Biology Center, T.J.Watson Research Center, Yorktown Heights, NY, USA., Haussler D; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA, USA., Margolin AA; Computational Biology Program, Oregon Health & Science University, Portland, OR, USA. adam.margolin@mssm.edu.; Sage Bionetworks, Seattle, WA, USA. adam.margolin@mssm.edu., Stuart JM; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA, USA. jstuart@ucsc.edu., Boutros PC; Ontario Institute for Cancer Research, Toronto, Ontario, Canada. paul.boutros@oicr.on.ca.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. paul.boutros@oicr.on.ca.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. paul.boutros@oicr.on.ca.
Publikováno v:
Genome biology [Genome Biol] 2018 Nov 06; Vol. 19 (1), pp. 188. Date of Electronic Publication: 2018 Nov 06.
Autor:
Espiritu SMG; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Liu LY; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Rubanova Y; Department of Computer Science, University of Toronto, Toronto, ON M5S 3G4, Canada; Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON M5S 3E1, Canada., Bhandari V; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Holgersen EM; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Szyca LM; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Fox NS; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Chua MLK; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada., Yamaguchi TN; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Heisler LE; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Livingstone J; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Wintersinger J; Department of Computer Science, University of Toronto, Toronto, ON M5S 3G4, Canada; Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON M5S 3E1, Canada., Yousif F; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Lalonde E; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Rouette A; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Salcedo A; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Houlahan KE; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Li CH; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Huang V; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada., Fraser M; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada., van der Kwast T; Department of Pathology and Laboratory Medicine, Toronto General Hospital/University Health Network, Toronto, ON M5S 1A1, Canada., Morris QD; Department of Computer Science, University of Toronto, Toronto, ON M5S 3G4, Canada; Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON M5S 3E1, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Vector Institute for Artificial Intelligence, Toronto, ON M5G 1M1, Canada. Electronic address: quaid.morris@utoronto.ca., Bristow RG; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada. Electronic address: robert.bristow@manchester.ac.uk., Boutros PC; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: paul.boutros@oicr.on.ca.
Publikováno v:
Cell [Cell] 2018 May 03; Vol. 173 (4), pp. 1003-1013.e15. Date of Electronic Publication: 2018 Apr 19.
Autor:
Rota SG; Department of Food Science, University of Guelph, Guelph, Ontario, Canada.; School of Pharmacy, University of Waterloo, Kitchener, Ontario, Canada., Roma A; Department of Food Science, University of Guelph, Guelph, Ontario, Canada.; School of Pharmacy, University of Waterloo, Kitchener, Ontario, Canada., Dude I; School of Pharmacy, University of Waterloo, Kitchener, Ontario, Canada., Ma C; School of Pharmacy, University of Waterloo, Kitchener, Ontario, Canada., Stevens R; Grand River Cancer Centre, Kitchener, Ontario, Canada., MacEachern J; Grand River Cancer Centre, Kitchener, Ontario, Canada., Graczyk J; Grand River Cancer Centre, Kitchener, Ontario, Canada., Espiritu SMG; Department of Biology, University of Waterloo, Waterloo, Ontario, Canada., Rao PN; School of Pharmacy, University of Waterloo, Kitchener, Ontario, Canada., Minden MD; Princess Margaret Cancer Center, Ontario Cancer Institute, Toronto, Ontario, Canada., Kreinin E; School of Pharmacy, University of Waterloo, Kitchener, Ontario, Canada., Hess DA; Robarts Research Institute, University of Western Ontario, London, Ontario, Canada., Doxey AC; Department of Biology, University of Waterloo, Waterloo, Ontario, Canada., Spagnuolo PA; Department of Food Science, University of Guelph, Guelph, Ontario, Canada. paul.spagnuolo@uoguelph.ca.; School of Pharmacy, University of Waterloo, Kitchener, Ontario, Canada.
Publikováno v:
Molecular cancer therapeutics [Mol Cancer Ther] 2017 Nov; Vol. 16 (11), pp. 2618-2626. Date of Electronic Publication: 2017 Aug 23.