Výsledky vyhledávání - "Espinosa Magali"

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Akademický článek

Depletion of the oncoprotein Bcl-3 induces centrosome amplification and aneuploidy in cancer cells

Autor: Zamora Ruben, Espinosa Magali, Ceballos-Cancino Gisela, Segura Blanca, Maldonado Vilma, Melendez-Zajgla Jorge

Publikováno v: Molecular Cancer, Vol 9, Iss 1, p 223 (2010)

Abstract Bcl-3 is an atypical member of the inhibitor of NF-kappa B family of proteins since it can function as a coactivator of transcription. Although this oncogene was described in leukemia, it is overexpressed in a number of solid tumors as well.

Externí odkaz: https://doaj.org/article/c5d6ba429ad64234b88ca0cb4fbaf2ce

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Akademický článek

High Smac/DIABLO expression is associated with early local recurrence of cervical cancer

Autor: Maldonado Vilma, De la Garza Jaime G, Espinosa Magali, Cantu David, Perez Delia, Garcia Francisco J, Arellano-Llamas Abril, Melendez-Zajgla Jorge

Publikováno v: BMC Cancer, Vol 6, Iss 1, p 256 (2006)

Abstract Background In a recent pilot report, we showed that Smac/DIABLO mRNA is expressed de novo in a subset of cervical cancer patients. We have now expanded this study and analyzed Smac/DIABLO expression in the primary lesions in 109 cervical can

Externí odkaz: https://doaj.org/article/aab6dd7cfeb64cedb589350f963181a7

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Akademický článek

Inhibitors of apoptosis proteins in human cervical cancer

Autor: De la Garza Jaime G, Lopez Carlos M, Herrera Norma, Cantú David, Espinosa Magali, Maldonado Vilma, Melendez-Zajgla Jorge

Publikováno v: BMC Cancer, Vol 6, Iss 1, p 45 (2006)

Abstract Background It has been shown that IAPs, in particular XIAP, survivin and c-IAP1, are overexpressed in several malignancies. In the present study we investigate the expression of c-IAP1, c-IAP2, XIAP and survivin and its isoforms in cervical

Externí odkaz: https://doaj.org/article/a1a70295ba064865b717c0716cc96174

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Akademický článek

SMAC is expressed de novo in a subset of cervical cancer tumors

Autor: Maldonado Vilma A, De la Garza Jaime G, Lopez Carlos M, Cantu David, Espinosa Magali, Melendez-Zajgla Jorge

Publikováno v: BMC Cancer, Vol 4, Iss 1, p 84 (2004)

Abstract Background Smac/Diablo is a recently identified protein that is released from mitochondria after apoptotic stimuli. It binds IAPs, allowing caspase activation and cell death. In view of its activity it might participate in carcinogenesis. In

Externí odkaz: https://doaj.org/article/32a1c0e218df40f58a35aebeb58b2e2d

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