PD-L1 at the crossroad between RNA metabolism and immunosuppression

Autor: Arthur, Axel, Nejmi, Sanae, Franchini, Don-Marc, Espinos, Estelle, Millevoi, Stefania

Publikováno v: In Trends in Molecular Medicine July 2024 30(7):620-632

T-Type α 1H Ca 2+ Channels Are Involved in Ca 2+ Signaling during Terminal Differentiation (Fusion) of Human Myoblasts

Autor: Bijlenga, Philippe, Liu, Jian-Hui, Espinos, Estelle, Haenggeli, Charles-Antoine, Fischer-Lougheed, Jacqueline, Bader, Charles R., Bernheim, Laurent

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2000 Jun . 97(13), 7627-7632.

Externí odkaz: https://www.jstor.org/stable/122864

Gene Expression Signature Associated with Clinical Outcome in ALK-Positive Anaplastic Large Cell Lymphoma

Autor: Camille, Daugrois, Chloé, Bessiere, Sébastien, Dejean, Véronique, Anton, Thérèse, Commes, Pyronnet, Stephane, Brousset, Pierre, Espinos, Estelle, Laurence, Brugiere, MEGGETTO, FABIENNE, Lamant, Laurence

Publikováno v: Cancers
Cancers, MDPI, 2021, 13 (21), ⟨10.3390/cancers13215523⟩
Cancers, MDPI, 2021, 13 (21), pp.5523. ⟨10.3390/cancers13215523⟩
Cancers, Vol 13, Iss 5523, p 5523 (2021)
Cancers, 2021, 13 (21), ⟨10.3390/cancers13215523⟩

Simple Summary Anaplastic large cell lymphomas associated with ALK translocation have a good outcome after CHOP treatment; however, the 2-year relapse rate remains at 30%. Microarray gene-expression profiling, high throughput RT-qPCR, and RNA sequenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a24c0f9b2a6f0003e487b1cc3bb04219
https://hal.inrae.fr/hal-03796758

Blockade of crizotinib-induced BCL2 elevation in ALK-positive anaplastic large cell lymphoma triggers autophagy associated with cell death

Autor: Torossian, Avedis, Broin, Nicolas, Frentzel, Julie, Daugrois, Camille, Gandarillas, Sarah, Saati, Talal Al, Lamant, Laurence, Brousset, Pierre, Giuriato, Sylvie, Espinos, Estelle

Publikováno v: Haematologica

Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphomas are tumors that carry translocations involving the ALK gene at the 2p23 locus, leading to the expression of ALK tyrosine kinase fusion oncoproteins. Amongst hematologic maligna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::98bd918cf8f45566f1b5c3e467223e63
http://europepmc.org/articles/PMC6601090

Des niveaux élevés de miR-7-5p potentialisent le cytokilling induit par le crizotinib et le flux autophagique en ciblant RAF1 dans les cellules de lymphome positives NPM-ALK

Autor: Sorrentino, Domenico, Frentzel, Julie, Mitou, Géraldine, Blasco, Rafael, Torossian, Avédis, Hoareau-Aveilla, Coralie, Pighi, Chiara, Farcé, Manon, MEGGETTO, FABIENNE, Manenti, Stéphane, Espinos, Estelle, Chiarle, Roberto, Giuriato, Sylvie

Publikováno v: Cancers
Cancers, MDPI, 2020, 12 (10), pp.2951. ⟨10.3390/cancers12102951⟩

International audience; Anaplastic lymphoma kinase positive anaplastic large cell lymphomas are a pediatric disease, which still needs treatment improvement. Crizotinib was the first ALK-targeted inhibitor used in clinics, but relapses are now known

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d64d34606301ec9581250083f3ffc3e8
https://hal.archives-ouvertes.fr/hal-03073848