Dual-drug loaded nanoparticles of Epigallocatechin-3-gallate (EGCG)/Ascorbic acid enhance therapeutic efficacy of ECGC in a APPswe/PS1dE9 Alzheimer's disease mice model

Autor: Cano Fernández, Amanda, Ettcheto Arriola, Miren, Chang, Jui-Hsien, Barroso Fernández, Emma, Espina García, Marta, Kühne, Britta A., Barenys Espadaler, Marta, Auladell i Costa, M. Carme, Folch, Jaume, Souto, Eliana B., Camins Espuny, Antoni, Turowski, Patrick, García López, María Luisa

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

Epigallocatechin-3-gallate (EGCG) is a candidate for treatment of Alzheimer's disease (AD) but its inherent instability limits bioavailability and effectiveness. We found that EGCG displayed increased stability when formulated as dualdrug loaded PEGy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::86f8398babacacb30465703a42116017
http://hdl.handle.net/2445/152238

Comparative Study of Ex Vivo Transmucosal Permeation of Pioglitazone Nanoparticles for the Treatment of Alzheimer’s Disease

Autor: Silva Abreu, Marcelle, Espinoza, Lupe Carolina, Halbaut, Lyda, Espina García, Marta, García López, María Luisa, Calpena Campmany, Ana Cristina

Publikováno v: Polymers
Polymers, Vol 10, Iss 3, p 316 (2018)
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Pioglitazone has been reported in the literature to have a substantial role in the improvement of overall cognition in a mouse model. With this in mind, the aim of this study was to determine the most efficacious route for the administration of Piogl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::35b42345507b43f424ae5ba0506786b9
http://europepmc.org/articles/PMC6414928

Evaluación del Practicum en industria del Master Universitario de Investigación, Desarrollo y Control de Medicamentos

Autor: García López, María Luisa, Egea Gras, Ma. Antonia, Calpena Campmany, Ana Cristina, González Mira, Elisabet, Fernández Campos, Francisco, Bielsa, R., Espina García, Marta, Gamisans Linares, Fidencia, García Celma, Ma José, Morral Ruíz, Genoveva, Nikolic, S., Salvadó, M. A. (M. Àngels), Souto, Eliana B., Valls, Oriol, Vega, E., Oliva, Mireia (Oliva Herrera), Bel Prieto, Elvira, Boix Montañés, Antonio de Pádua, Clares Naveros, Beatriz, Colom Codina, Helena, Escribano Ferrer, Elvira, Esteve, J. (Jesus), Flo, Anna, Garduño Ramírez, María Luisa del Carmen, Lauroba Viladrosa, Jacinto

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Podeu consultar la Setena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/43352
El principal objetivo de este estudio, que forma parte del proyecto REDICE2010, fue evaluar el practicum de industria del Más

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fde2ab9097b28571e919f13842ae853f
http://hdl.handle.net/2445/51043

Influence of freeze-drying and γ-irradiation in preclinical studies of flurbiprofen polymeric nanoparticles for ocular delivery using d-(+)-trehalose and polyethylene glycol.

Autor: Ramos Yacasi, Gladys Rosario, García López, María Luisa, Espina García, Marta, Coca, Alexander Parra, Calpena Campmany, Ana Cristina

Publikováno v: International Journal of Nanomedicine; 2016, Vol. 11, p4093-4106, 14p

Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization

Autor: Sánchez-López, E. (Elena), Ettcheto, Miren, Egea Gras, Ma. Antonia, Espina García, Marta, Cano, Amanda, Calpena Campmany, Ana Cristina, Camins Espuny, Antoni, Carmona, Nuria, Silva, Amélia M, Souto, Eliana B., García, Maria Luisa

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Journal of Nanobiotechnology
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-16 (2018)

Background Memantine, drug approved for moderate to severe Alzheimer’s disease, has not shown to be fully effective. In order to solve this issue, polylactic-co-glycolic (PLGA) nanoparticles could be a suitable solution to increase drug’s action

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3659052844c5d74f31eff684a098a009
http://hdl.handle.net/2445/122302