Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Espen Molden"'
Autor:
Marta H. Hernandez, Jacqueline M. Cohen, Karoline H. Skåra, Thea K. Grindstad, Yunsung Lee, Per Magnus, Pål R. Njølstad, Ole A. Andreassen, Elizabeth C. Corfield, Alexandra Havdahl, Espen Molden, Kari Furu, Maria C. Magnus, Alvaro Hernaez
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109285- (2024)
Summary: Low birth weight raises neonatal risks and lifelong health issues and is linked to maternal medication use during pregnancy. We examined data from the Norwegian Mother, Father, and Child Cohort Study and the Medical Birth Registry of Norway,
Externí odkaz:
https://doaj.org/article/e30fa6344ada4cb6aaa0e9e53d4984dc
Autor:
Robert Løvsletten Smith, Birgit M. Wollmann, Elisabet Størset, Hasan Çağın Lenk, Kevin S. O'Connell, Marianne Kringen Kristiansen, Magnus Ingelman‐Sundberg, Espen Molden
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract Cytochrome P450 2D6 (CYP2D6) is important for metabolism of 20%–25% of all clinically used drugs. Many known genetic variants contribute to the large interindividual variability in CYP2D6 metabolism, but much is still unexplained. We recen
Externí odkaz:
https://doaj.org/article/bc583d3f16e243a881eff9ea3dbfb57a
Autor:
Pari Faraj, Elisabet Størset, Kristine Hole, Godfrey Smith, Espen Molden, Erik Sveberg Dietrichs
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104779- (2023)
Summary: Background: For a decade, patients have been advised against using high citalopram- and escitalopram-doses due to risk for ventricular arrhythmia and cardiac arrest. Still, these drugs are widely used to treat depression and anxiety especial
Externí odkaz:
https://doaj.org/article/e9dd8f7480494aac94df61a7749140a7
Autor:
Hasan Çağın Lenk, Robert Løvsletten Smith, Kevin S. O'Connell, Marin M. Jukić, Marianne Kristiansen Kringen, Ole A. Andreassen, Magnus Ingelman‐Sundberg, Espen Molden
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 1, Pp 62-72 (2023)
Abstract Clinical response of clozapine is closely associated with serum concentration. Although tobacco smoking is the key environmental factor underlying interindividual variability in clozapine metabolism, recent genome‐wide studies suggest that
Externí odkaz:
https://doaj.org/article/b404641d026a4bb681d473f000373fe3
Autor:
Line Skute Bråten, Magnus Ingelman‐Sundberg, Marin M. Jukic, Espen Molden, Marianne Kristiansen Kringen
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 9, Pp 2135-2145 (2022)
Abstract Sertraline is a commonly used SSRI antidepressant drug, metabolized by CYP2C19 and CYP2B6, that exhibits a substantial interindividual variation in clinical response, of which only a part can be attributed to known genetic variants. In the c
Externí odkaz:
https://doaj.org/article/65875f5235c64f31969d93433786b3a6
Publikováno v:
BMC Geriatrics, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background In older patients with polypharmacy and multiple comorbidities, even low grades of statin-associated muscle symptoms may have clinical implications. The aim of this study was therefore to investigate the potential associations bet
Externí odkaz:
https://doaj.org/article/2ede51c200ea4fb6a527fa203186bf64
Autor:
Lisbeth Damlien Nymoen, Trude Eline Flatebø, Tron Anders Moger, Erik Øie, Espen Molden, Kirsten Kilvik Viktil
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Introduction The main objective of this study was to investigate whether systematic medication review conducted by clinical pharmacists can impact clinical outcomes and post-discharge outcomes for patients admitted to the emergency department. Method
Externí odkaz:
https://doaj.org/article/ac70373ce242405487cacfdc0fa53b0f
Autor:
Espen Molden, Marin M. Jukić
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Genetic differences in cytochrome P450 (CYP)-mediated metabolism have been known for several decades. The clinically most important polymorphic CYP enzyme is CYP2D6, which plays a key role in the metabolism of many antidepressants and antipsychotics,
Externí odkaz:
https://doaj.org/article/cdde0d6ff9ad490aa46f39588e1f5868
Publikováno v:
BMJ Open, Vol 10, Iss 12 (2020)
Objective To investigate the effect of pharmacist-led medicines management in multimorbid, hospitalised patients on long-term hospital readmissions and survival.Design Parallel-group, randomised controlled trial.Setting Recruitment from an internal m
Externí odkaz:
https://doaj.org/article/784a5ec6500944cd957de7a8284a01c1
Autor:
Rita Romskaug, Espen Molden, Jørund Straand, Hege Kersten, Eva Skovlund, Kaisu H Pitkala, Torgeir Bruun Wyller
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Polypharmacy and inappropriate drug use is associated with negative health outcomes among older people. Various interventions for improving drug treatment have been evaluated, but the majority of studies are limited by the use of
Externí odkaz:
https://doaj.org/article/b1be3a6f7f094430bd674143316681ae