Výsledky vyhledávání - "Espérance Mukawera"

Akademický článek

Ozone inactivation of airborne influenza and lack of resistance of respiratory syncytial virus to aerosolization and sampling processes.

Autor: Marie-Eve Dubuis, Étienne Racine, Jonathan M Vyskocil, Nathalie Turgeon, Christophe Tremblay, Espérance Mukawera, Guy Boivin, Nathalie Grandvaux, Caroline Duchaine

Publikováno v: PLoS ONE, Vol 16, Iss 7, p e0253022 (2021)

Influenza and RSV are human viruses responsible for outbreaks in hospitals, long-term care facilities and nursing homes. The present study assessed an air treatment using ozone at two relative humidity conditions (RHs) in order to reduce the infectiv

Externí odkaz: https://doaj.org/article/4b3bfdce9a4a4351b08e611d25614cf2

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Akademický článek

The Combination of IFN β and TNF Induces an Antiviral and Immunoregulatory Program via Non-Canonical Pathways Involving STAT2 and IRF9

Autor: Mélissa K. Mariani, Pouria Dasmeh, Audray Fortin, Elise Caron, Mario Kalamujic, Alexander N. Harrison, Diana I. Hotea, Dacquin M. Kasumba, Sandra L. Cervantes-Ortiz, Espérance Mukawera, Adrian W. R. Serohijos, Nathalie Grandvaux

Publikováno v: Cells, Vol 8, Iss 8, p 919 (2019)

Interferon (IFN) β and Tumor Necrosis Factor (TNF) are key players in immunity against viruses. Compelling evidence has shown that the antiviral and inflammatory transcriptional response induced by IFNβ is reprogrammed by crosstalk with TNF. IFNβ

Externí odkaz: https://doaj.org/article/811b0e3d9df2455c91cf63ce5d52d40c

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Akademický článek

Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression.

Autor: Anton Soucy-Faulkner, Espérance Mukawera, Karin Fink, Alexis Martel, Loubna Jouan, Yves Nzengue, Daniel Lamarre, Christine Vande Velde, Nathalie Grandvaux

Publikováno v: PLoS Pathogens, Vol 6, Iss 6, p e1000930 (2010)

The innate immune response is essential to the host defense against viruses, through restriction of virus replication and coordination of the adaptive immune response. Induction of antiviral genes is a tightly regulated process initiated mainly throu

Externí odkaz: https://doaj.org/article/d4e84708d269456d9238b3a1367552c0

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Ozone inactivation of airborne influenza and lack of resistance of respiratory syncytial virus to aerosolization and sampling processes

Autor: Caroline Duchaine, Guy Boivin, Nathalie Grandvaux, Nathalie Turgeon, Christophe Tremblay, Jonathan M. Vyskocil, Espérance Mukawera, Marie-Eve Dubuis, Etienne Racine

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0253022 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105a119475fcb1580109e49b35456b0d
https://pubmed.ncbi.nlm.nih.gov/34252093

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The Combination of IFN β and TNF Induces an Antiviral and Immunoregulatory Program via Non-Canonical Pathways Involving STAT2 and IRF9

Autor: Mario Kalamujic, Mélissa K. Mariani, Sandra Cervantes-Ortiz, Pouria Dasmeh, Alexander N. Harrison, Espérance Mukawera, Elise Caron, Audray Fortin, Dacquin M. Kasumba, Adrian W.R. Serohijos, Diana Ioana Hotea, Nathalie Grandvaux

Publikováno v: Cells
Volume 8
Issue 8
Cells, Vol 8, Iss 8, p 919 (2019)

Interferon (IFN) &beta
and Tumor Necrosis Factor (TNF) are key players in immunity against viruses. Compelling evidence has shown that the antiviral and inflammatory transcriptional response induced by IFN&beta
is reprogrammed by crosstalk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0823831d5f055f6110146dc10e445707

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IFNβ and TNFα cooperate to induce a STAT1-independent antiviral and immunoregulatory program via non-canonical STAT2 and IRF9 pathways

Autor: Sandra Cervantes-Ortiz, Mélissa K. Mariani, Espérance Mukawera, Audray Fortin, Elise Caron, Pouria Dasmeh, Mario Kalamujic, Nathalie Grandvaux, Dacquin M. Kasumba, Adrian W.R. Serohijos, Alexander N. Harrison

IFNβ typically induces an antiviral and immunoregulatory transcriptional program through the activation of ISGF3 (STAT1, STAT2 and IRF9) transcriptional complexes. The response to IFNβ is context-dependent and is prone to crosstalk with other cytok

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366d63f7cfdf94be78f8ce221bb80ac2
https://doi.org/10.1101/273623

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DUSP1 regulates apoptosis and cell migration, but not the JIP1-protected cytokine response, during Respiratory Syncytial Virus and Sendai Virus infection

Autor: Nathalie Grandvaux, Alexa C. Robitaille, Audray Fortin, Anaïs Gélinas, Mélissa K. Mariani, Emmanuelle Brochiero, Damien Adam, Espérance Mukawera, Nicolas Zucchini, Elise Caron

Publikováno v: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)

The host antiviral response involves the induction of interferons and proinflammatory cytokines, but also the activation of cell death pathways, including apoptosis, to limit viral replication and spreading. This host defense is strictly regulated to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ebfb36d9f56b99af3789fe50ef57ef
http://europepmc.org/articles/PMC5727028

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IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH Oxidase-mediated airway antiviral response

Autor: Espérance Mukawera, Françoise Miot, Xavier De Deken, Nathalie Grandvaux, Lydie Martin, Karin Fink, Emmanuelle Brochiero, Stéfany Chartier

Publikováno v: Cell Research. 23:673-690

Airway epithelial cells are key initial innate immune responders in the fight against respiratory viruses, primarily via the secretion of antiviral and proinflammatory cytokines that act in an autocrine/paracrine fashion to trigger the establishment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdb880282f7723d46c4a87999508c1c
https://doi.org/10.1038/cr.2013.47

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Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression

Autor: Yves Nzengue, Anton Soucy-Faulkner, Christine Vande Velde, Loubna Jouan, Alexis Martel, Karin Fink, Daniel Lamarre, Espérance Mukawera, Nathalie Grandvaux

Publikováno v: PLoS Pathogens, Vol 6, Iss 6, p e1000930 (2010)
PLoS Pathogens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f10e359d051098ccec7151f6629a7f
http://europepmc.org/articles/PMC2880583?pdf=render

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Respiratory Syncytial Virus-Mediated NF-κB p65 Phosphorylation at Serine 536 Is Dependent on RIG-I, TRAF6, and IKKβ▿

Autor: Nathalie Grandvaux, Fabrice Yoboua, Alexis Martel, Espérance Mukawera, Annick Duval

Respiratory syncytial virus (RSV) is the etiological agent of acute respiratory diseases, such as bronchiolitis and pneumonia. The exacerbated production of proinflammatory cytokines and chemokines in the airways in response to RSV is an important pi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87a5363fa760c23a16ec6ec00df4af2
https://europepmc.org/articles/PMC2898247/

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