Zobrazeno 1 - 10
of 404
pro vyhledávání: '"Esophageal epithelium"'
Autor:
Alena Klochkova, Adam L. Karami, Annie D. Fuller, Louis R. Parham, Surali R. Panchani, Shruthi Natarajan, Jazmyne L. Jackson, Anbin Mu, Yinfei Tan, Kathy Q. Cai, Andres J. Klein-Szanto, Amanda B. Muir, Marie-Pier Tétreault, Xavier Graña, Kathryn E. Hamilton, Kelly A. Whelan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 1, Pp 15-40 (2024)
Background & Aims: Autophagy plays roles in esophageal pathologies both benign and malignant. Here, we aim to define the role of autophagy in esophageal epithelial homeostasis. Methods: We generated tamoxifen-inducible, squamous epithelial-specific A
Externí odkaz:
https://doaj.org/article/10798208ac324620b1299c8ac2877db4
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 5, Pp 713-718 (2024)
Eosinophilic esophagitis (EoE) is an emerging form of food allergy that exerts a significant clinical and financial burden worldwide. EoE is clinically characterized by eosinophil-rich inflammatory infiltrates in esophageal mucosa and esophageal dysf
Externí odkaz:
https://doaj.org/article/cb814a89b8054a00b4aee11f5b159408
Autor:
Annie D. Fuller, Adam L. Karami, Mohammad Faujul Kabir, Alena Klochkova, Jazmyne L. Jackson, Anbin Mu, Yinfei Tan, Andres J. Klein-Szanto, Kelly A. Whelan
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
IntroductionUnder homeostatic conditions, esophageal epithelium displays a proliferation/differentiation gradient that is generated as proliferative basal cells give rise to suprabasal cells then terminally differentiated superficial cells. This prol
Externí odkaz:
https://doaj.org/article/bfa60c20b4244bd9b9ed3cd95ddddc6d
Autor:
Alena Klochkova, Annie D. Fuller, Riley Miller, Adam L. Karami, Surali R. Panchani, Shruthi Natarajan, Anbin Mu, Jazmyne L. Jackson, Andres J. Klein-Szanto, Amanda B. Muir, Kelly A. Whelan
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
Subepithelial fibrosis occurs in a subset of eosinophilic esophagitis (EoE) patients and is associated with esophageal stricture. While mechanisms driving EoE fibrosis remain incompletely understood, findings from experimental systems support roles f
Externí odkaz:
https://doaj.org/article/70fd8a55c4ad44cc9bb32754ad67cee8
Akademický článek
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Akademický článek
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Autor:
Jaiza Samara Macena de Araújo, Maria Cristina Volpato, Bruno Vilela Muniz, Gabriela Gama Augusto Xavier, Claudia Cristina Maia Martinelli, Renata Fonseca Vianna Lopez, Francisco Carlos Groppo, Michelle Franz-Montan
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 643 (2021)
Permeation assays are important for the development of topical formulations applied on buccal mucosa. Swine buccal and esophageal epithelia are usually used as barriers for these assays, while frozen epithelia have been used to optimize the experimen
Externí odkaz:
https://doaj.org/article/17507a140ed341cdaadff638974d526d
Autor:
Edyta Korbut, Vincent T Janmaat, Mateusz Wierdak, Jerzy Hankus, Dagmara Wójcik, Marcin Surmiak, Katarzyna Magierowska, Tomasz Brzozowski, Maikel P Peppelenbosch, Marcin Magierowski
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6436 (2020)
Barrett’s esophagus (BE) is a premalignant condition caused by gastroesophageal reflux disease (GERD), where physiological squamous epithelium is replaced by columnar epithelium. Several in vivo and in vitro BE models were developed with questionab
Externí odkaz:
https://doaj.org/article/57e2af1037e2465d940a0718935134a9
Publikováno v:
Терапевтический архив, Vol 93, Iss 4, Pp 521-525 (2021)
The data on association between various pathologies of the ENT organs and gastroesophageal reflux disease (GERD) is analysed in the article. The variety of extraesophageal signs of GERD in children and adults is given, what is advisable to inform phy
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 731 (2019)
Pendrin (SLC26A4), a Cl−/anion exchanger, is expressed at high levels in kidney, thyroid, and inner ear epithelia, where it has an essential role in bicarbonate secretion/chloride reabsorption, iodide accumulation, and endolymph ion balance, respec
Externí odkaz:
https://doaj.org/article/34c19b349ea34f9399f12d29cc07acc7