Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Esophageal Neoplasms/drug therapy"'
Autor:
Yuichiro, Doki, Jaffer A, Ajani, Ken, Kato, Jianming, Xu, Lucjan, Wyrwicz, Satoru, Motoyama, Takashi, Ogata, Hisato, Kawakami, Chih-Hung, Hsu, Antoine, Adenis, Farid, El Hajbi, Maria, Di Bartolomeo, Maria I, Braghiroli, Eva, Holtved, Sandra A, Ostoich, Hye R, Kim, Masaki, Ueno, Wasat, Mansoor, Wen-Chi, Yang, Tianshu, Liu, John, Bridgewater, Tomoki, Makino, Ioannis, Xynos, Xuan, Liu, Ming, Lei, Kaoru, Kondo, Apurva, Patel, Joseph, Gricar, Ian, Chau, Yuko, Kitagawa, Rachna T, Shroff
Publikováno v:
Doki, Y, Ajani, J A, Kato, K, Xu, J, Wyrwicz, L, Motoyama, S, Ogata, T, Kawakami, H, Hsu, C H, Adenis, A, El Hajbi, F, Di Bartolomeo, M, Braghiroli, M I, Holtved, E, Ostoich, S A, Kim, H R, Ueno, M, Mansoor, W, Yang, W C, Liu, T, Bridgewater, J, Makino, T, Xynos, I, Liu, X, Lei, M, Kondo, K, Patel, A, Gricar, J, Chau, I, Kitagawa, Y & CheckMate 648 Trial Investigators 2022, ' Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma ', The New England Journal of Medicine, vol. 386, no. 5, pp. 449-462 . https://doi.org/10.1056/NEJMoa2111380
BACKGROUND: First-line chemotherapy for advanced esophageal squamous-cell carcinoma results in poor outcomes. The monoclonal antibody nivolumab has shown an overall survival benefit over chemotherapy in previously treated patients with advanced esoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756f60de0ad71943361b198f70779f11
https://pubmed.ncbi.nlm.nih.gov/35660032
https://pubmed.ncbi.nlm.nih.gov/35660032
Autor:
Josefine Slater, Daniel Kjær, Arunas Pikelis, Torben Ingemann Petersen, M. B. Nielsen, Birgitte Jul Kiil, Sune Brinck Erichsen, Marianne Nordsmark, Niels Katballe
Publikováno v:
Erichsen, S B, Slater, J, Kiil, B J, Petersen, T I, Katballe, N, Nielsen, M B, Pikelis, A, Nordsmark, M & Kjaer, D 2022, ' Oncological results and morbidity following intended curative resection and free jejunal graft reconstruction of cervical esophageal cancer : a retrospective Danish consecutive cohort study ', Diseases of the Esophagus (Online), vol. 35, no. 3, doab048 . https://doi.org/10.1093/dote/doab048
Summary Background The role of surgery in treatment of locally advanced cervical esophageal cancer (CEC) remains debated. In the European and American treatment guidelines, definitive chemoradiotherapy (dCRT) is preferred over surgery, while in the D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b7443e9e99df352a6a796c6acadea9
https://doi.org/10.1093/dote/doab048
https://doi.org/10.1093/dote/doab048
Publikováno v:
Der Chirurg, Vol. 92, No 6 (2021) pp. 515-521
Zusammenfassung: HINTERGRUND: Zum Zeitpunkt der Diagnosestellung des Magenkarzinoms haben ca. zwei Drittel der Patienten bereits Metastasen. Wichtig ist es, die Oligometastasierung von der diffus metastasierten Situation abzugrenzen. Die S3-Leitlinie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1400::40e9e341031bf7cafcf7c7ca05717b9f
https://archive-ouverte.unige.ch/unige:158685
https://archive-ouverte.unige.ch/unige:158685
Autor:
Nicola Valeri, Heike I. Grabsch, David Cunningham, Matthew Nankivell, Nasser Davarzani, William H. Allum, Ruth E Langley, Nicholas P. West, Gordon G A Hutchins, Elizabeth C Smyth, Lindsay C. Hewitt
Publikováno v:
Histopathology, 72(7), 1180-1188. Wiley
Histopathology
Histopathology
Aims: Neoadjuvant chemotherapy (NAC) remains an important therapeutic option for advanced oesophageal cancer (OC). Pathological tumour regression grade (TRG) may offer additional information by directing adjuvant treatment and/or follow-up but its cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7acf1e4d389ae98c013816ac7447f7
https://doi.org/10.1111/his.13491
https://doi.org/10.1111/his.13491
Autor:
Dreilich, Martin, Bergqvist, Michael, Moberg, Martin, Brattström, Daniel, Gustavsson, Inger, Bergström, Stefan, Wanders, Alkwin, Hesselius, Patrik, Wagenius, Gunnar, Gyllensten, Ulf
BACKGROUND: Human papilloma virus (HPV) in patients with esophageal carcinoma has previously been studied with an average detection rate of 15%, but the role of HPV in relation to survival is less clear. In cervical cancer, lung cancer and tonsil can
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-94408
Autor:
Christopher Cardwell, Richard C. Turkington, James Trainor, Andrew D. Spence, Stephen McQuaid, Jacqueline James, Damian T. McManus, Victoria Bingham, Helen G. Coleman, Brian T. Johnston, Manuel Salto-Tellez, Úna C. McMenamin
Publikováno v:
Spence, A D, Trainor, J, McMenamin, Ú, Turkington, R C, McQuaid, S, Bingham, V, James, J, Salto-Tellez, M, McManus, D T, Johnston, B T, Cardwell, C R & Coleman, H G 2019, ' High PTGS2 expression in post neoadjuvant chemotherapy treated oesophageal adenocarcinoma is associated with improved survival: a population-based cohort study ', Histopathology, vol. 74, no. 4, pp. 587-596 . https://doi.org/10.1111/his.13786
Aims High prostaglandin endoperoxide synthase-2 (PTGS2) enzyme expression in oesophageal adenocarcinoma has been shown to independently predict poor prognosis; however, the evidence is inconsistent. The aim of this study was to investigated the assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f29e17871cf6773dd2258f0ee19ecc7
https://pure.qub.ac.uk/en/publications/e2bd61ad-1814-4612-8b6b-16f3c64da3ae
https://pure.qub.ac.uk/en/publications/e2bd61ad-1814-4612-8b6b-16f3c64da3ae
Autor:
Chong, Irene Yushing, Aronson, Lauren, Bryant, Hanna, Gulati, Aditi, Campbell, James, Elliott, Richard, Pettitt, Stephen, Wilkerson, Paul, Lambros, Maryou B, Reis-Filho, Jorge S, Ramessur, Anisha, Davidson, Michael, Chau, Ian, Cunningham, David, Ashworth, Alan, Lord, Christopher J
Publikováno v:
Chong, I Y, Aronson, L, Bryant, H, Gulati, A, Campbell, J, Elliott, R, Pettitt, S, Wilkerson, P, Lambros, M B, Reis-Filho, J S, Ramessur, A, Davidson, M, Chau, I, Cunningham, D, Ashworth, A & Lord, C J 2018, ' Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer ', Gut, vol. 67, no. 10, pp. 1780-1792 . https://doi.org/10.1136/gutjnl-2017-314408
OBJECTIVE: Oesophageal cancer is the seventh most common cause of cancer-related death worldwide. Disease relapse is frequent and treatment options are limited.DESIGN: To identify new biomarker-defined therapeutic approaches for patients with oesopha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::160dfc08aa38f91a8e5a0691eafda4c4
https://www.pure.ed.ac.uk/ws/files/79604473/1780.full.pdf
https://www.pure.ed.ac.uk/ws/files/79604473/1780.full.pdf
Autor:
Magdalena Jadwiga Utsch, Anna Krilova, Özlem Türeci, Martin Schuler, Karl Dhaene, Markus Jerling, Christoph Rohde, Stefan Bauer, Tobias Dechow, Ugur Sahin, Heike Richly, Christoph Huber
Introduction IMAB362 (Zolbetuximab) is a chimeric monoclonal antibody that binds to Claudin-18.2, a target antigen specific to cancer cells. In vitro, IMAB362 mediates cell death through antibody-dependent cellular cytotoxicity and complement-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb9949f013111d7e7dd98d889459c98
https://doi.org/10.1016/j.ejca.2018.05.007
https://doi.org/10.1016/j.ejca.2018.05.007
Autor:
Dangxiao Cheng, Zhuo Chen, Henry Thai, Trevor Morey, Laurie Ailles, Osvaldo Espin-Garcia, Joerg Schwock, Lucy Liu, Helen Mackay, Hala Girgis, Jennifer Teichman, Geoffrey Liu, Andrew Fleet, Gail Darling, Wei Xu, Madison McGregor, Yuyao Song, Robert G. Bristow, Yonathan Brhane, Lorin Dodbiba
Publikováno v:
PLoS ONE
Teichman, J, Dodbiba, L, Thai, H, Fleet, A, Morey, T, Liu, L, McGregor, M, Cheng, D, Chen, Z, Darling, G, Brhane, Y, Song, Y, Espin-Garcia, O, Xu, W, Girgis, H, Schwock, J, MacKay, H, Bristow, R, Ailles, L & Liu, G 2018, ' Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma ', PLoS ONE, vol. 13, no. 5, pp. e0194809 . https://doi.org/10.1371/journal.pone.0194809
PLoS ONE, Vol 13, Iss 5, p e0194809 (2018)
Teichman, J, Dodbiba, L, Thai, H, Fleet, A, Morey, T, Liu, L, McGregor, M, Cheng, D, Chen, Z, Darling, G, Brhane, Y, Song, Y, Espin-Garcia, O, Xu, W, Girgis, H, Schwock, J, MacKay, H, Bristow, R, Ailles, L & Liu, G 2018, ' Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma ', PLoS ONE, vol. 13, no. 5, pp. e0194809 . https://doi.org/10.1371/journal.pone.0194809
PLoS ONE, Vol 13, Iss 5, p e0194809 (2018)
BACKGROUND: The Hedgehog (Hh) signaling pathway is active in esophageal adenocarcinoma (EAC). We used a patient-derived murine xenograft (PDX) model of EAC to evaluate tumour response to conventional treatment with radiation/chemoradiation with or wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba143b2fd9699ec9f7d0ce18b82f7ba
http://europepmc.org/articles/PMC5929523
http://europepmc.org/articles/PMC5929523
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