Výsledky vyhledávání - "Esohe Idusogie"

Analytical Methods Used to Characterize Fc-Fusion Proteins

Autor: Esohe Idusogie, Michael Mulkerrin

Publikováno v: Therapeutic Fc-Fusion Proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16b17222507a0bcd3a652f0190cd6873
https://doi.org/10.1002/9783527675272.ch07

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Characterization of a cDNA Encoding Murine Coagulation Factor VII

Autor: Esohe Idusogie, Peter Carmeliet, Jie Ping Geng, Desire Collen, Elliot D. Rosen, Francis J. Castellino

Publikováno v: Thrombosis and Haemostasis. 75:481-487

SummaryThe cDNA encoding murine coagulation factor VII (mfVII) was isolated and reconstructed from a Λ Zap cDNA library generated from murine liver mRNA. The cDNA contains 1903 nucleotides spanning 15 bases upstream of the 5’-translation initiatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d26d91bc41bc5edc838ee9af2cfef76d
https://doi.org/10.1055/s-0038-1650301

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Abstract 1549: Development and validation of a biomarker for prospective selection of Notch1 activation in patients with certain advanced solid tumors in a first-in-human phase1 study of the cancer stem cell targeting antibody OMP-52M51 (anti-Notch1)

Autor: Esohe Idusogie, Bryan McCune, Lori Johnson, Ann M. Kapoun, Raymond Tam, John Lewicki, Tim Hoey, Steve Anderson, Chun Zhang, Belinda Cancilla

Publikováno v: Cancer Research. 75:1549-1549

Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA The Notch pathway plays a key role in embryonic development, the regulation of stem and progenitor cells, and is implicated centrally in many forms of human cancer. Notc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74c64453675f0517deedf1ae05bacab4
https://doi.org/10.1158/1538-7445.am2015-1549

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Mice lacking factor VII develop normally but suffer fatal perinatal bleeding

Autor: Peter Carmeliet, Liang Zhong, Frédéric Clotman, Thomas Luther, Joyce Chi Yee Chan, Ann Lissens, Luc Schoonjans, Elliot D. Rosen, George P. Vlasuk, Sybille Albrecht, Louise R. Jalbert, Francis J. Castellino, Lieve Moons, Esohe Idusogie, Desire Collen

Publikováno v: Nature. 390(6657)

Blood coagulation in vivo is initiated by factor VII (FVII) binding to its cellular receptor tissue factor (TF)(1-4). FVII is the only known ligand for TF, so it was expected that FVII-deficient embryos would have a similar phenotype to TF-deficient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefab5009195730771c49081536978ab
https://pubmed.ncbi.nlm.nih.gov/9384381

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Nucleotide structure and characterization of the murine blood coagulation factor VII gene

Autor: Francis J. Castellino, Esohe Idusogie, Desire Collen, Peter Carmeliet, Elliot D. Rosen

Publikováno v: Thrombosis and haemostasis. 76(6)

SummaryThe gene encoding murine coagulation factor VII (fVII) has been cloned. Seven introns and eight exons are present, with the introns positioned as splice junctions between the major domain units of the protein. A total of 11,748 bp of the gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9f8472b716c00b95b8dce0b6c2060c
https://pubmed.ncbi.nlm.nih.gov/8972017

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