Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Esmaeil, Mansouri"'
Autor:
Nadia Boachie, Erin Gaudette, Richard P. Bazinet, Lin Lin, Rachel F. Tyndale, Esmaeil Mansouri, Marilyn A. Huestis, Junchao Tong, Bernard Le Foll, Stephen J. Kish, Tony P. George, Isabelle Boileau
Publikováno v:
Brain Sciences, Vol 13, Iss 10, p 1375 (2023)
Background: Endocannabinoids and related N-acylethanolamines (NAEs) are bioactive lipids with important physiological functions and putative roles in mental health and addictions. Although chronic cannabis use is associated with endocannabinoid syste
Externí odkaz:
https://doaj.org/article/c15397b4384f4b5dbc0cffdffb8ba890
Autor:
Patricia Di Ciano, Harriet de Wit, Esmaeil Mansouri, Sylvain Houle, Isabelle Boileau, Bernard Le Foll
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Stimuli previously paired with drugs of dependence can produce cravings that are associated with increased dopamine (DA) levels in limbic and striatal brain areas. Positron Emission Tomography (PET) imaging with [11C]-(+)-PHNO allows for a s
Externí odkaz:
https://doaj.org/article/43c3cb03aec84e3ea43938674f3d4922
Autor:
Esmaeil Mansouri, Bernard Le Foll, Matthew D. McPhee, Isabelle Boileau, Dafna S. Rubin-Kahana, Christian S. Hendershot, Chidera C. Chukwueke, Christina N Nona, Diana Martinez
Publikováno v:
Neuropsychopharmacology. 46:2112-2120
Preclinical studies support an important role of dopamine D3 receptors (DRD3s) in alcohol use disorder (AUD). In animals, voluntary alcohol consumption increases DRD3 expression, and pharmacological blockade of DRD3s attenuates alcohol self-administr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5b25cfcd65d367739a745111833a5c3
https://doi.org/10.1038/s41386-021-01095-2
https://doi.org/10.1038/s41386-021-01095-2
Autor:
Harriet de Wit, Bernard Le Foll, Isabelle Boileau, Patricia Di Ciano, Sylvain Houle, Esmaeil Mansouri
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Scientific Reports
Scientific Reports
Stimuli previously paired with drugs of dependence can produce cravings that are associated with increased dopamine (DA) levels in limbic and striatal brain areas. Positron Emission Tomography (PET) imaging with [11C]-(+)-PHNO allows for a sensitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c761ea178d22635f9b8d6ea0d5a5ede4
https://doaj.org/article/43c3cb03aec84e3ea43938674f3d4922
https://doaj.org/article/43c3cb03aec84e3ea43938674f3d4922
Autor:
Claudia Poluga, Malika Querido, Nadia Boachie, Rachel F. Tyndale, Stefan Kloiber, Nathan Kolla, Laura M. Best, Esmaeil Mansouri, Bernard Le Foll, Stephen J. Kish, Jerry Warsh, Tony George, Isabelle Boileau
Publikováno v:
Biological Psychiatry. 93:S250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f337265db611013726e15ac2368fc6f
https://doi.org/10.1016/j.biopsych.2023.02.626
https://doi.org/10.1016/j.biopsych.2023.02.626
Autor:
Thierry Duvauchelle, Philippe Robert, Pablo Rusjan, Pamela Sabioni, Isabelle Boileau, Patricia Di Ciano, Bernard Le Foll, Marc Capet, Jean-Charles Schwartz, Esmaeil Mansouri, Alexia Laveillé
Publikováno v:
British Journal of Pharmacology. 177:3464-3472
Background and purpose BF2.649 (pitolisant, Wakix®) is a novel histamine H3 receptor inverse agonist/antagonist recently approved for the treatment of narcolepsy disorder. The objective of the study was to investigate in vivo occupancy of H3 recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::505492d54cee86108180eb81f9e387c0
https://doi.org/10.1111/bph.15067
https://doi.org/10.1111/bph.15067
Autor:
Rachel F. Tyndale, Belinda Williams, Christian S. Hendershot, Richard P. Bazinet, Markus Heilig, Sylvain Houle, Isabelle Boileau, Junchao Tong, Vincenzo De Luca, Pablo Rusjan, Laura M. Best, Bernard Le Foll, Dina Lagzdins, Stephen J. Kish, Lin Lin, Esmaeil Mansouri, Alan A. Wilson
Publikováno v:
Neuropsychopharmacology
The endocannabinoid enzyme, fatty acid amide hydrolase (FAAH), has been proposed as a therapeutic target for alcohol use disorder (AUD) and co-morbid psychiatric illnesses. Investigating this target in the living human brain and its relationship to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c3a36d2a158be549f7d48d6265ef46
https://doi.org/10.1038/s41386-020-0606-2
https://doi.org/10.1038/s41386-020-0606-2
Autor:
Bernard Le Foll, Junchao Tong, Alan A. Wilson, Philippe Robert, Sylvain Houle, Patricia Di Ciano, Jean Schwartz, Isabelle Boileau, Esmaeil Mansouri, Thierry Duvauchelle
Publikováno v:
Neuropsychopharmacology. 44:1284-1290
There has been considerable interest in the development of dopamine D3 receptor (DRD3) partial agonists and antagonists for the treatment of substance use disorders. Pre-clinical evidence overwhelmingly supports the use of these drugs, but translatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e44091218fe6981aa3e5ae64ccc6132
https://doi.org/10.1038/s41386-018-0285-4
https://doi.org/10.1038/s41386-018-0285-4
Autor:
Isabelle Boileau, Alan A. Wilson, Dina Lagzdins, Patricia Di Ciano, Sylvain Houle, Bernard Le Foll, Rachel F. Tyndale, Esmaeil Mansouri, Christian S. Hendershot
Publikováno v:
International Journal of Neuropsychopharmacology
Background Identifying the biological basis of smoking cessation success is of growing interest. The rate of nicotine metabolism, measured by the nicotine metabolite ratio, affects multiple aspects of nicotine dependence. Fast nicotine metabolizers t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3972168a90e41506297a7470514e07bd
https://doi.org/10.1093/ijnp/pyx119
https://doi.org/10.1093/ijnp/pyx119
Autor:
Sylvain Houle, Stephen J. Kish, Shinichiro Nakajima, Isabelle Boileau, Susan R. George, Belinda Williams, Esmaeil Mansouri, Romina Mizrahi, Suzanna Stevanovski, Bernard Le Foll, Tony P. George, Doris Payer
Publikováno v:
Psychoneuroendocrinology. 76:192-196
Corticotropin-releasing hormone (CRH) is a key component of the neuroendocrine response to stress. In animal models, CRH has been shown to modulate dopamine release, and this interaction is believed to contribute to stress-induced relapse in neuropsy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e39255c068d9bd9ea9c923ea41f95c3
https://doi.org/10.1016/j.psyneuen.2016.11.034
https://doi.org/10.1016/j.psyneuen.2016.11.034