Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Eslam E. Abd El-Fattah"'
Autor:
Eslam E. Abd El-Fattah, Amr Y. Zakaria
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Liver fibrosis is a liver disease in which there is an excessive buildup of extracellular matrix proteins, including collagen. By regulating cytokine production and the inflammatory response, heat shock proteins (HSPs) contribute significant
Externí odkaz:
https://doaj.org/article/3f4d52487607478aba8adc9d0976db30
Autor:
Eslam E. Abd El-Fattah
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Cancer is one of the leading causes of death in both men and women worldwide. One of the main changes associated with cancer progression, metastasis, recurrence, and chemoresistance is the change in the tumor immune microenvironment, especia
Externí odkaz:
https://doaj.org/article/7086dfb2d2ae450fa18d75a7f6d12139
Autor:
Sameh Saber, Eslam E. Abd El-Fattah, Amir Mohamed Abdelhamid, Ahmed A.E. Mourad, Manal Ali Mahrous Hamouda, Amr Elrabat, Sahar Zakaria, Amira A. Haleem, Sherin Z. Mohamed, Rehab Mohamed Elgharabawy, Nesreen Elsayed Morsy, Noura El Adle Khalaf, Osama A. Mohammed, Waleed Barakat El-Bahouty, Sally Abdallah Mostafa, Rasha Abdelhady, Omneya Galal, Zeinab H. ElSaid, Galal Yahya, Ahmed Shata, Mahmoud E. Youssef
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114196- (2023)
Hepatocellular carcinoma (HCC) is the third foremost cause of cancer-related deaths. HCC has a very bad prognosis because it is asymptomatic in the early stages, resulting in a late diagnosis, and it is highly resistant to conventional chemotherapy.
Externí odkaz:
https://doaj.org/article/0d31de0bd8a14b35a099acad7c4590a3
Autor:
Amir Mohamed Abdelhamid, Sameh Saber, Mahmoud E. Youssef, Ahmed Gaafar Ahmed Gaafar, Hanan Eissa, Marwa A. Abd-Eldayem, Mohammed Alqarni, Gaber El-Saber Batiha, Ahmad J. Obaidullah, Mohamed Awad Shahien, Eman El-Ahwany, Noha A. Amin, Mohamed Ali Etman, Mohamed M.Y. Kaddah, Eslam E. Abd El-Fattah
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112455- (2022)
Hepatocellular carcinoma (HCC) is on the rise worldwide, and its incidence in diabetic patients is two to three times that of non-diabetics. Current therapeutic options fail to provide considerable survival benefits to patients with HCC. There is a s
Externí odkaz:
https://doaj.org/article/243e31ff9d064d9ab4bb5a9d133137d8
Autor:
Eslam E. Abd El-Fattah, Sameh Saber, Mahmoud E. Youssef, Hanan Eissa, Eman El-Ahwany, Noha A. Amin, Mohammed Alqarni, Gaber El-Saber Batiha, Ahmad J. Obaidullah, Mohamed M.Y. Kaddah, Ahmed Gaafar Ahmed Gaafar, Ahmed A.E. Mourad, Gomaa Mostafa-Hedeab, Amir Mohamed Abdelhamid
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
HIF-1α is a key factor promoting the development of hepatocellular carcinoma (HCC). As well, AKT-AMPKα-mTOR signaling is a promising target for cancer therapy. Yet, the AKT-AMPKα-mTOR-dependent activation of HIF-1α has not been studied in livers
Externí odkaz:
https://doaj.org/article/bef7df31734f402aafc87c7e96643e3f
Autor:
Mahmoud E. Youssef, Eslam E. Abd El-Fattah, Amir M. Abdelhamid, Hanan Eissa, Eman El-Ahwany, Noha A. Amin, Helal F. Hetta, Mohamed H. Mahmoud, Gaber El-Saber Batiha, Naglaa Gobba, Ahmed Gaafar Ahmed Gaafar, Sameh Saber
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Empagliflozin and metformin are widely used for the treatment of type 2 diabetes. These drugs showed marked anti-inflammatory effects in different animal models via enhancing AMPK activity. Yet, the protective anti-inflammatory effects of their combi
Externí odkaz:
https://doaj.org/article/4045624fd37a4f088375bcbe34339cb9
Autor:
Sameh Saber, Eslam E. Abd El-Fattah, Galal Yahya, Naglaa A. Gobba, Abdalkareem Omar Maghmomeh, Ahmed E. Khodir, Ahmed A. E. Mourad, Ahmed S. Saad, Hager G. Mohammed, Nehal A. Nouh, Ahmed Shata, Noha A. Amin, Magdy Abou El-Rous, Samuel Girgis, Eman El-Ahwany, Eman M. Khalaf, Attalla F. El-Kott, Ahmed M. El-Baz
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 341 (2021)
Inflammasome targeting and controlling dysbiosis are promising therapeutic approaches to control ulcerative colitis. This report is the first to investigate the mechanisms underlying the coloprotective effects of rosuvastatin and Lactobacillus and th
Externí odkaz:
https://doaj.org/article/8ec2dda160bc4147b50f5a6b97896fe4
Publikováno v:
International immunopharmacology. 113
Hepatocellular carcinoma (HCC) is the most common type of liver cancer. There are different therapeutic approaches to cancer eradication such as chemotherapy, radiotherapy, and surgery. The fuel for treatment resistance is heterogeneity, which also h
Autor:
Eslam E, Abd El-Fattah
Publikováno v:
International Immunopharmacology. 114:109568
Cancer is a disease caused when cells divide uncontrollably and spread into surrounding tissues. There are different therapeutic modalities that control cancer growth, of which surgery, chemotherapy, and radiotherapy. Chemotherapy is a cancer treatme
Autor:
Noha A. Amin, Ahmad J. Obaidullah, Sameh Saber, Mahmoud E. Youssef, Eslam E. Abd El-Fattah, Mohammed Alqarni, Eman El-Ahwany, Mohamed Ali Etman, Mohamed Awad Shahien, Marwa A. Abd-Eldayem, Hanan Eissa, Gaber El-Saber Batiha, Amir Mohamed Abdelhamid, Mohamed M.Y. Kaddah, Ahmed Gaafar Ahmed Gaafar
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss, Pp 112455-(2022)
Hepatocellular carcinoma (HCC) is on the rise worldwide, and its incidence in diabetic patients is two to three times that of non-diabetics. Current therapeutic options fail to provide considerable survival benefits to patients with HCC. There is a s