Administrativní budova ESKO-T, stavebně technologický projekt

Autor: Vochyán, David

The aim of this thesis is compile building and technological project of new office building of the company ESKO-T in Třebíč. This is a two-storey building, build technology cast-in-place longitudinal reinforced concrete frame with mono-pitched roo

Externí odkaz: http://www.nusl.cz/ntk/nusl-265518

Disentangling the consequences of type 2 diabetes on targeted metabolite profiles using causal inference and interaction QTL analyses.

Autor: Bocher O; Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany., Singh A; Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.; Munich School for Data Science (MUDS), Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich (TUM), TUM School of Medicine and Health, Graduate School of Experimental Medicine, Munich, Germany., Huang Y; Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich (TUM), TUM School of Medicine and Health, Graduate School of Experimental Medicine, Munich, Germany., Võsa U; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Reimann E; Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Arruda A; Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.; Munich School for Data Science (MUDS), Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich (TUM), TUM School of Medicine and Health, Graduate School of Experimental Medicine, Munich, Germany., Barysenska A; Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany., Kolde A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia., Rayner NW; Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany., Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Zeggini E; Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.; TUM school of medicine and health, Technical University Munich and Klinikum Rechts der Isar, Munich, Germany.

Publikováno v: PLoS genetics [PLoS Genet] 2024 Dec 03; Vol. 20 (12), pp. e1011346. Date of Electronic Publication: 2024 Dec 03.

Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.

Autor: Zheng SL; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Henry A; Institute of Cardiovascular Science, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK., Cannie D; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Lee M; National Heart and Lung Institute, Imperial College London, London, UK., Miller D; Division of Biosciences, University College London, London, UK., McGurk KA; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bond I; Institute of Cardiovascular Science, University College London, London, UK., Xu X; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Issa H; Institute of Health Informatics, University College London, London, UK., Francis C; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., De Marvao A; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Theotokis PI; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Buchan RJ; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Speed D; Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark., Abner E; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Adams L; Geisinger Health System, Danville, PA, USA., Aragam KG; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ärnlöv J; Department of Neurobiology, Care Sciences and Society/Section of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.; School of Health and Social Sciences, Dalarna University, Falun, Sweden., Raja AA; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Backman JD; Analytical Genetics, Regeneron Genetics Center, Tarrytown, NY, USA., Baksi J; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Barton PJR; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Biddinger KJ; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Boersma E; Erasmus MC, Cardiovascular Institute, Thorax Center, Department of Cardiology, Utrecht, the Netherlands., Brandimarto J; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Brunak S; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bundgaard H; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Carey DJ; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA., Charron P; Sorbonne Research Unit on Cardiovascular Disorders, Metabolism and Nutrition, Team Genomics & Pathophysiology of Cardiovascular Diseases, ICAN Institute for Cardiometabolism and Nutrition, Paris, France.; APHP, Department of Genetics, Pitié-Salpêtrière Hospital, Paris, France., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Cook SA; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Denaxas S; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK, University College London, London, UK.; British Heart Foundation Data Science Centre, London, UK.; The National Institute for Health Research University College London Hospitals Biomedical Research Centre, University College London, London, UK., Deleuze JF; Centre National de Recherche en Génomique Humaine (CNRGH), Institut de Biologie François Jacob, CEA, Université Paris-Saclay, Evry, France.; Laboratory of Excellence GENMED (Medical Genomics), Paris, France.; Centre d'Etude du Polymorphisme Humain, Fondation Jean Dausset, Paris, France., Doney AS; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Elliott P; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Erikstrup C; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.; Deparment of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Farber-Eger EH; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Finan C; Institute of Cardiovascular Science, University College London, London, UK., Garnier S; Sorbonne Research Unit on Cardiovascular Disorders, Metabolism and Nutrition, Team Genomics & Pathophysiology of Cardiovascular Diseases, ICAN Institute for Cardiometabolism and Nutrition, Paris, France., Ghouse J; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden., Guðbjartsson DF; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Haggerty CM; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA., Halliday BP; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Helgadottir A; deCODE genetics/Amgen Inc., Reykjavik, Iceland., Hemingway H; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK, University College London, London, UK., Hillege HL; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Kardys I; Erasmus MC, Cardiovascular Institute, Thorax Center, Department of Cardiology, Utrecht, the Netherlands., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Lindgren CM; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Lowery BD; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Manisty C; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Margulies KB; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Moon JC; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Mordi IR; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Morley MP; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Morris AD; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK., Morton L; Cardiovascular Research, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Noursadeghi M; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK., Ostrowski SR; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen University Hospital, Copenhagen, Denmark., Owens AT; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Palmer CNA; Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Pantazis A; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Pedersen OBV; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark., Prasad SK; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Shekhar A; Cardiovascular Research, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Smelser DT; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA., Srinivasan S; Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Stefansson K; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Medicine, University of Iceland, Reykjavik, Iceland., Sveinbjörnsson G; deCODE genetics/Amgen Inc., Reykjavik, Iceland., Syrris P; Institute of Cardiovascular Science, University College London, London, UK., Tammesoo ML; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Tayal U; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Teder-Laving M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Thorgeirsson G; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Medicine, University of Iceland, Reykjavik, Iceland., Thorsteinsdottir U; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Medicine, University of Iceland, Reykjavik, Iceland., Tragante V; deCODE genetics/Amgen Inc., Reykjavik, Iceland., Trégouët DA; Laboratory of Excellence GENMED (Medical Genomics), Paris, France.; Univ. Bordeaux, INSERM, BPH, Bordeaux, France., Treibel TA; Institute of Cardiovascular Science, University College London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, London, UK., Ullum H; Statens Serum Institut, Copenhagen, Denmark., Valdes AM; Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham, UK., van Setten J; Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., van Vugt M; Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Veluchamy A; Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Verschuren WMM; Department Life Course, Lifestyle and Health, Centre for Prevention, Lifestyle and Health, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands., Villard E; Sorbonne Research Unit on Cardiovascular Disorders, Metabolism and Nutrition, Team Genomics & Pathophysiology of Cardiovascular Diseases, ICAN Institute for Cardiometabolism and Nutrition, Paris, France., Yang Y; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Asselbergs FW; Institute of Cardiovascular Science, University College London, London, UK.; The National Institute for Health Research University College London Hospitals Biomedical Research Centre, University College London, London, UK.; Department of Cardiology, Amsterdam University Medical Centers, Amsterdam, the Netherlands., Cappola TP; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Dube MP; Montreal Heart Institute, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Dunn ME; Cardiovascular Research, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Ellinor PT; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Hingorani AD; Institute of Cardiovascular Science, University College London, London, UK., Lang CC; Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.; Tuanku Muhriz Chair, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia., Samani NJ; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Shah SH; Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC, USA.; Duke Clinical Research Institute, Durham, NC, USA.; Duke Molecular Physiology Institute, Durham, NC, USA., Smith JG; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.; Department of Molecular and Clinical Medicine, Institute of Medicine, Gothenburg University and Sahlgrenska University Hospital, Gothenburg, Sweden.; Wallenberg Center for Molecular Medicine and Lund University Diabetes Center, Lund University, Lund, Sweden., Vasan RS; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Sections of Cardiology, Preventive Medicine and Epidemiology, Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, MA, USA., O'Regan DP; MRC Laboratory of Medical Sciences, London, UK., Holm H; deCODE genetics/Amgen Inc., Reykjavik, Iceland., Noseda M; National Heart and Lung Institute, Imperial College London, London, UK., Wells Q; Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN, USA., Ware JS; National Heart and Lung Institute, Imperial College London, London, UK. j.ware@imperial.ac.uk.; MRC Laboratory of Medical Sciences, London, UK. j.ware@imperial.ac.uk.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK. j.ware@imperial.ac.uk.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA. j.ware@imperial.ac.uk., Lumbers RT; Institute of Health Informatics, University College London, London, UK. t.lumbers@ucl.ac.uk.; Health Data Research UK, University College London, London, UK. t.lumbers@ucl.ac.uk.; British Heart Foundation Data Science Centre, London, UK. t.lumbers@ucl.ac.uk.

Publikováno v: Nature genetics [Nat Genet] 2024 Nov 21. Date of Electronic Publication: 2024 Nov 21.

Developing and validating a comprehensive polygenic risk score to enhance keratoconus risk prediction.

Autor: He W; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, St Lucia, Queensland 4072, Australia., Võsa U; Department of Genetics, University Medical Centre Groningen Medical Faculty building (building 3211) 5th floor, Antonius Deusinglaan 1 9713 AV Groningen, The Netherlands.; Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, Estonia., Palumaa T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, Estonia.; Eye Clinic, East Tallinn Central Hospital, Ravi street 18, 10138 Tallinn, Estonia.; Department of Ophthalmology, Emory University, 201 Dowman Dr NE, Atlanta, GA 30322, United States., Ong JS; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland 4006, Australia., Torres SD; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, St Lucia, Queensland 4072, Australia., Hewitt AW; Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool St, Hobart Tasmania 7000, Australia.; Centre for Eye Research Australia, University of Melbourne, Peter Howson Wing, Level 7, 32 Gisborne Street, Melbourne East Victoria 3002, Australia., Mackey DA; Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, 2 Verdun Street, Nedlands, Western Australia 6009, Australia., Gharahkhani P; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, St Lucia, Queensland 4072, Australia.; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, R Block, Kelvin Grove Campus Victoria Park Road, Kelvin Grove, Queensland 4059, Australia., Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, Estonia., MacGregor S; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, St Lucia, Queensland 4072, Australia.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2024 Nov 13. Date of Electronic Publication: 2024 Nov 13.

High incidence and geographic distribution of cleft palate in Finland are associated with the IRF6 gene.

Autor: Rahimov F; Department of Human Genetics, Genomics Research Center, AbbVie Inc, North Chicago, IL, 60064, USA., Nieminen P; Orthodontics, Department of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, 00014, Finland., Kumari P; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, 52242, USA.; Department of Oral Health Sciences, University of Washington, Seattle, WA, 98195, USA., Juuri E; Orthodontics, Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, 00014, Finland.; Cleft Palate and Craniofacial Center, Department of Plastic Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, 00029 HUS, Finland., Nikopensius T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., Paraiso K; Environmental Genomics and Systems Biology Division, Lawrence Berkeley Laboratories, Berkeley, CA, 94720, USA.; U.S. Department of Energy Joint Genome Institute, Lawrence Berkeley Laboratories, Berkeley, CA, 94720, USA., German J; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, 00014, Finland.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA., Karvanen A; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, 00014, Finland., Kals M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia.; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, 00014, Finland., Elnahas AG; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., Karjalainen J; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, 00014, Finland.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA., Kurki M; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, 00014, Finland.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, 00014, Finland.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA., Heliövaara A; Cleft Palate and Craniofacial Center, Department of Plastic Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, 00029 HUS, Finland., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., Jukarainen S; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, 00014, Finland., Palta P; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia.; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, 00014, Finland., Ganna A; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, 00014, Finland., Patni AP; Department of Oral Health Sciences, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington School of Medicine, Seattle, WA, 98195, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA, 98109, USA.; Cancer Biology and Stem Cell Biology Laboratory, Department of Genetic Engineering, School of Bioengineering, College of Engineering and Technology, SRM Institute of Science and Technology, Chennai, 603203, India., Mar D; Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA, 98109, USA.; UW Medicine South Lake Union, University of Washington, Seattle, WA, 98109, USA., Bomsztyk K; Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA, 98109, USA.; UW Medicine South Lake Union, University of Washington, Seattle, WA, 98109, USA.; Matchstick Technologies, Inc, Kirkland, WA, 98033, USA., Mathieu J; Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA, 98109, USA.; Department of Comparative Medicine, University of Washington School of Medicine, Seattle, WA, 98195, USA., Ruohola-Baker H; Department of Oral Health Sciences, University of Washington, Seattle, WA, 98195, USA.; Department of Biochemistry, University of Washington School of Medicine, Seattle, WA, 98195, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA, 98109, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, 98195, USA.; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA., Visel A; Environmental Genomics and Systems Biology Division, Lawrence Berkeley Laboratories, Berkeley, CA, 94720, USA.; U.S. Department of Energy Joint Genome Institute, Lawrence Berkeley Laboratories, Berkeley, CA, 94720, USA.; School of Natural Sciences, University of California, Merced, CA, 95343, USA., Fakhouri WD; Department of Diagnostic and Biomedical Sciences, School of Dentistry, University of Texas Health Science Center at Houston, Houston, TX, 77054, USA.; Department of Pediatrics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Schutte BC; Department of Microbiology, Genetics and Immunology, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, 48824, USA. schutteb@msu.edu., Cornell RA; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, 52242, USA. cornellr@uw.edu.; Department of Oral Health Sciences, University of Washington, Seattle, WA, 98195, USA. cornellr@uw.edu.; Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA, 98109, USA. cornellr@uw.edu., Rice DP; Orthodontics, Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, 00014, Finland. david.rice@helsinki.fi.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 06; Vol. 15 (1), pp. 9568. Date of Electronic Publication: 2024 Nov 06.