Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Eskiler Gg"'
Autor:
Oztopcu-Vatan P, Yılmaz Altuner, Eskiler Gg, Sila Appak-Baskoy, Ozgun Teksoy, Namık Bilici, Ozkan Ad, Mustafa Cengiz, Adnan Ayhanci, Sahin lK
Treatment options to improve overall survival rate of prostate cancer patients are limited since tumor cells acquire resistance to the chemotherapeutic drugs. We aimed to determine anticancer effects of stone alkaline water (SAW) on PC-3 and DU-145 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3b7dfb5b871e166ef009e33bc6f1f5
Autor:
Gamze Guney Eskiler
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 22, Iss 1 (2019)
Purpose: Aberrant activation of the phosphatidylinositol 3'-kinase (PI3K)-Akt signaling pathway is observed in many types of human cancer including triple negative breast cancer (TNBC). Additionally, dysregulation in the homologous recombination (HR)
Autor:
Gamze Guney Eskiler
Publikováno v:
Drugs of today (Barcelona, Spain : 1998). 55(7)
Talazoparib tosylate (BMN-673, Talzenna; Pfizer) is an oral poly [ADP-ribose] polymerase (PARP) inhibitor (PARPi) that has been approved by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for the treatment of germl
Autor:
Beste Yurdacan, Unal Egeli, Güney Eskiler, Gamze, Isil Ezgi Eryilmaz, Gulsah Cecener, Berrin Tunca
Objectives Sorafenib (SOR) is an orally administered molecular targeted agent in the systemic chemotherapy of hepatocellular carcinoma (HCC). However, the partial response of SOR is limited due to its adverse side effect and high heterogeneity and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbda2ff99885b60b1de4366aca61327
http://hdl.handle.net/11452/33037
http://hdl.handle.net/11452/33037
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 22, Iss 1 (2019)
Purpose: Toll-like receptor 4 (TLR4) is over-expressed in breast tumors and thus contributing to the tumor progression and metastasis. Natural products have drawn attention in cancer immunotherapy due to their various biological activities. Curcumin
Publikováno v:
Nutrition and cancer. 71(8)
Objective: Herein we, for the first time, investigated a potential synergistic effect of nobiletin (NOB) and sorafenib (SOR) on PC-3 prostate cancer and HUVEC control cell lines. Methods: In order to determine the cytotoxic and apoptotic effects of t
Autor:
Beste Yurdacan, Gulsah Cecener, Berrin Tunca, Unal Egeli, Isil Ezgi Eryilmaz, Gamze Guney Eskiler
Usnic acid (UA) is a multifunctional bioactive lichen secondary metabolite with potential anti-cancer properties. Although the promising therapeutic effects of UA have been investigated in different cancer cell lines, the mechanism driving UA-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d2439b7c32adeef4ccc60edbb1ef2e
https://hdl.handle.net/20.500.12619/71938
https://hdl.handle.net/20.500.12619/71938
The objective of the present study was to elucidate the effect of BMN 673 (talozoparib) on BRCA1 mutant (HCC1937) and wild-type (MDA-MB-231) triple negative breast cancer (TNBC). The in vitro cytotoxicity results indicated that BMN 673 had considerab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8fd1072c7ceafbe5f8472ef48314c4
https://hdl.handle.net/20.500.12619/71178
https://hdl.handle.net/20.500.12619/71178
Autor:
Gamze Guney Eskiler, İbrahim Kani
Background The synthesis of new ligand and transition metal complexes have drawn great attention in cancer treatment due to excellent DNA cleavage activities and high antitumor activity. Objective The purpose of this study was to synthesize a new Zn(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244c0be0510fd97310d4096d5a52c3b8
https://hdl.handle.net/20.500.12619/65647
https://hdl.handle.net/20.500.12619/65647
Autor:
Guney G. Eskiler, Güney Eskiler, Gamze, E. Bezdegumeli, Z. Ozman, Deveci A. Ozkan, Deveci Özkan, Asuman, Bilir, Cemil, B. N. Kucukakca, M. N. Ince, A. Y. Men, O. Aktas, Y. E. Horoz, D. Akpinar
Objectives We investigated the changes in the IL-6 and STAT3 expression levels in cachectic and non-cachectic patients with gastric, lung and breast cancer and evaluated the association between IL-6 and STAT3 levels and cancer types in terms of cache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ce0e132bd73707da37b21cb2269358
https://hdl.handle.net/20.500.12619/65641
https://hdl.handle.net/20.500.12619/65641