Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Eskil ELMÉR"'
Autor:
Elisa Thoral, Carmen C. García-Díaz, Elin Persson, Imen Chamkha, Eskil Elmér, Suvi Ruuskanen, Andreas Nord
Publikováno v:
Biology Open, Vol 13, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/e99f1450cdf147bebb80e8bde66ed882
Autor:
Emil Westerlund, Sigurður E. Marelsson, Michael Karlsson, Fredrik Sjövall, Imen Chamkha, Eleonor Åsander Frostner, Johan Lundgren, Vineta Fellman, Erik A. Eklund, Katarina Steding-Ehrenborg, Niklas Darin, Gesine Paul, Magnus J. Hansson, Johannes K. Ehinger, Eskil Elmér
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26745- (2024)
There is a growing interest for the possibility of using peripheral blood cells (including platelets) as markers for mitochondrial function in less accessible tissues. Only a few studies have examined the correlation between respiration in blood and
Externí odkaz:
https://doaj.org/article/744a06f443954b8d975111204dbfd9ca
Autor:
Nora Li, Imen Chamkha, Gaurav Verma, Sabine Swoboda, Malin Lindstedt, Lennart Greiff, Eskil Elmér, Johannes Ehinger
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
IntroductionHead and neck squamous cell carcinoma (HNSCC) constitutes a heterogeneous group of cancers. Human papilloma virus (HPV) is associated with a subtype of HNSCC with a better response to treatment and more favorable prognosis. Mitochondrial
Externí odkaz:
https://doaj.org/article/5629022377d54ace9502c2b579fc7a6c
Autor:
Sarah Piel, Joanna I. Janowska, J. Laurenson Ward, Meagan J. McManus, Joshua S. Jose, Jonathan Starr, Malkah Sheldon, Carly L. Clayman, Eskil Elmér, Magnus J. Hansson, David H. Jang, Michael Karlsson, Johannes K. Ehinger, Todd J. Kilbaugh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Pesticides account for hundreds of millions of cases of acute poisoning worldwide each year, with organophosphates (OPs) being responsible for the majority of all pesticide-related deaths. OPs inhibit the enzyme acetylcholinesterase (AChE),
Externí odkaz:
https://doaj.org/article/3a5223e4d0324f0a8e19cb273dbd5e2b
Autor:
Åsa Nääv, Lena Erlandsson, Christina Isaxon, Eleonor Åsander Frostner, Johannes Ehinger, Moa K. Sporre, Annette M. Krais, Bo Strandberg, Thomas Lundh, Eskil Elmér, Ebba Malmqvist, Stefan R. Hansson
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Objective: Epidemiological studies have found air pollution to be a driver of adverse pregnancy outcomes, including gestational diabetes, low term birth weight and preeclampsia. It is unknown what biological mechanisms are involved in this process. A
Externí odkaz:
https://doaj.org/article/f606257b414e4486b152249ac5dfdef4
Autor:
Sarah Piel, Imen Chamkha, Adam Kozak Dehlin, Johannes K Ehinger, Fredrik Sjövall, Eskil Elmér, Magnus J Hansson
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231173 (2020)
Acetaminophen is one of the most common over-the-counter pain medications used worldwide and is considered safe at therapeutic dose. However, intentional and unintentional overdose accounts for up to 70% of acute liver failure cases in the western wo
Externí odkaz:
https://doaj.org/article/38c8ab6c0c2b4962a46ddb921cd97c16
Autor:
Sarah Piel, Johannes K. Ehinger, Imen Chamkha, Eleonor Åsander Frostner, Fredrik Sjövall, Eskil Elmér, Magnus J. Hansson
Publikováno v:
Intensive Care Medicine Experimental, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Metformin is the most common pharmacological treatment for type 2 diabetes. It is considered safe but has been associated with the development of lactic acidosis under circumstances where plasma concentrations exceed therapeutic l
Externí odkaz:
https://doaj.org/article/b766a7ad98dc49df8d06ab85f7ef9daa
Autor:
Saara Tegelberg, Nikica Tomašić, Jukka Kallijärvi, Janne Purhonen, Eskil Elmér, Eva Lindberg, David Gisselsson Nord, Maria Soller, Nicole Lesko, Anna Wedell, Helene Bruhn, Christoph Freyer, Henrik Stranneheim, Rolf Wibom, Inger Nennesmo, Anna Wredenberg, Erik A. Eklund, Vineta Fellman
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-14 (2017)
Abstract Background Mitochondrial diseases due to defective respiratory chain complex III (CIII) are relatively uncommon. The assembly of the eleven-subunit CIII is completed by the insertion of the Rieske iron-sulfur protein, a process for which BCS
Externí odkaz:
https://doaj.org/article/4f5b4fca633f4964a3749feb2ec9be5e
Autor:
Vlad Florian Avram, Anca Mihaela Bîna, Alexandra Sima, Oana Maria Aburel, Adrian Sturza, Ovidiu Burlacu, Romulus Zorin Timar, Danina Mirela Muntean, Eskil Elmér, Octavian Marius Crețu
Publikováno v:
Life, Vol 11, Iss 4, p 288 (2021)
Diabetes mellitus (DM) is the most severe metabolic disease that reached the level of a global pandemic and is associated with high cardiovascular morbidity. Statins are the first–line lipid–lowering therapy in diabetic patients with or without a
Externí odkaz:
https://doaj.org/article/5996aa97fbec4e69b58e2cb3e30a86fc
Autor:
Johannes K. Ehinger, Sarah Piel, Rhonan Ford, Michael Karlsson, Fredrik Sjövall, Eleonor Åsander Frostner, Saori Morota, Robert W. Taylor, Doug M. Turnbull, Clive Cornell, Steven J. Moss, Carsten Metzsch, Magnus J. Hansson, Hans Fliri, Eskil Elmér
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Mitochondrial complex I deficiency is the most common respiratory chain defect in mitochondrial disease in children and currently there is no effective treatment. In this study, the authors show that succinate prodrugs can alleviate metabolic decompe
Externí odkaz:
https://doaj.org/article/065e786aabe24902981472f3415f76d9