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neuronal enhancer network upstream of MEF2C is compromised in patients with Rett-like characteristics.

Autor: D'haene, Eva, Bar-Yaacov, Reut, Bariah, Inbar, Vantomme, Lies, Loo, Sien Van, Cobos, Francisco Avila, Verboom, Karen, Eshel, Reut, Alatawna, Rawan, Menten, Björn, Birnbaum, Ramon Y, Vergult, Sarah

Publikováno v: Human Molecular Genetics; 3/1/2019, Vol. 28 Issue 5, p818-827, 10p

Engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons.

Autor: Bracha S; Department of Neurobiology, Biochemistry and Biophysics, Wise Faculty of Life Sciences and Sagol School for Neuroscience, Tel Aviv University, Tel Aviv, Israel. shaharbr@mit.edu.; McGovern Institute for Brain Research, MIT, Cambridge, MA, USA. shaharbr@mit.edu., Johnson HJ; Neuroscience Graduate Interdisciplinary Program, University of Arizona, Tucson, AZ, USA.; Departments of Neurology and Immunobiology, College of Medicine, and BIO5 Institute, University of Arizona, Tucson, AZ, USA., Pranckevicius NA; Centre for Parasitology, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Catto F; Institute of Neuropathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Economides AE; Institute of Neuropathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Litvinov S; Computational Science and Engineering Laboratory, School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA., Hassi K; Centre for Parasitology, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Rigoli MT; Human Technopole, Milan, Italy.; Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Cheroni C; Human Technopole, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Bonfanti M; Human Technopole, Milan, Italy., Valenti A; Human Technopole, Milan, Italy.; Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Stucchi S; Human Technopole, Milan, Italy.; Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Attreya S; Undergraduate Biology Research Program, University of Arizona, Tucson, AZ, USA., Ross PD; Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK., Walsh D; Centre for Parasitology, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Malachi N; Epeius Pharma, Ness Ziona, Israel., Livne H; Epeius Pharma, Ness Ziona, Israel., Eshel R; Epeius Pharma, Ness Ziona, Israel., Krupalnik V; Epeius Pharma, Ness Ziona, Israel., Levin D; Epeius Pharma, Ness Ziona, Israel., Cobb S; Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK., Koumoutsakos P; Computational Science and Engineering Laboratory, School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA., Caporale N; Human Technopole, Milan, Italy.; Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Testa G; Human Technopole, Milan, Italy. giuseppe.testa@fht.org.; Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan, Italy. giuseppe.testa@fht.org.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy. giuseppe.testa@fht.org., Aguzzi A; Institute of Neuropathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland. adriano.aguzzi@usz.ch., Koshy AA; Departments of Neurology and Immunobiology, College of Medicine, and BIO5 Institute, University of Arizona, Tucson, AZ, USA. akoshy@arizona.edu., Sheiner L; Centre for Parasitology, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. lilach.sheiner@glasgow.ac.uk., Rechavi O; Department of Neurobiology, Biochemistry and Biophysics, Wise Faculty of Life Sciences and Sagol School for Neuroscience, Tel Aviv University, Tel Aviv, Israel. odedrechavi@gmail.com.

Publikováno v: Nature microbiology [Nat Microbiol] 2024 Aug; Vol. 9 (8), pp. 2051-2072. Date of Electronic Publication: 2024 Jul 29.