Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eshan S. King"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 2, p e1011878 (2024)
Mutant selection windows (MSWs), the range of drug concentrations that select for drug-resistant mutants, have long been used as a model for predicting drug resistance and designing optimal dosing strategies in infectious disease. The canonical MSW m
Externí odkaz:
https://doaj.org/article/526ff343403045e5bcfd9d460478085f
Autor:
Davis T Weaver, Benjamin D McElvany, Vishhvaan Gopalakrishnan, Kyle J Card, Dena Crozier, Andrew Dhawan, Mina N Dinh, Emily Dolson, Nathan Farrokhian, Masahiro Hitomi, Emily Ho, Tanush Jagdish, Eshan S King, Jennifer L Cadnum, Curtis J Donskey, Nikhil Krishnan, Gleb Kuzmin, Ju Li, Jeff Maltas, Jinhan Mo, Julia Pelesko, Jessica A Scarborough, Geoff Sedor, Enze Tian, Gary C An, Sean A Diehl, Jacob G Scott
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0241734 (2021)
Personal protective equipment (PPE) is crucially important to the safety of both patients and medical personnel, particularly in the event of an infectious pandemic. As the incidence of Coronavirus Disease 2019 (COVID-19) increases exponentially in t
Externí odkaz:
https://doaj.org/article/c9cb9eb3a2b1444ea76753df9db95399
Mutant selection windows (MSWs), the range of drug concentrations that select for drug-resistant mutants, have long been used as a model for predicting drug resistance and designing optimal dosing strategies in infectious disease. The canonical MSW m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2a7c9d3e32cc58b4ced27a5e864604
https://doi.org/10.1101/2023.03.09.531899
https://doi.org/10.1101/2023.03.09.531899
Autor:
Eshan S. King, Jeff Maltas, Davis T. Weaver, Rowan Barker-Clarke, Julia Pelesko, Emily Dolson, Jacob G. Scott
A persistent challenge in evolutionary medicine is predicting the evolution of drug resistance, which is complicated further when the drug concentration varies in time and space within a patient. Evolutionary trade-offs, or fitness costs of resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4646a6f957830d1d76821bfda0f7f5a
https://doi.org/10.1101/2022.06.10.495696
https://doi.org/10.1101/2022.06.10.495696
Publikováno v:
Cancer Research. 82:B027-B027
One approach to the study of therapy resistance is through an evolutionary lens, where novel sub-types emerge through a random process and are selected for by an increased fitness. Computational models are used to understand the parameter spaces that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9780963c53b17ed7d7034210c6210e28
https://doi.org/10.1158/1538-7445.evodyn22-b027
https://doi.org/10.1158/1538-7445.evodyn22-b027
Autor:
Ju Li, Masahiro Hitomi, Nikhil Krishnan, Kyle J. Card, Dena Crozier, Andrew Dhawan, Gleb Kuzmin, Sean A. Diehl, Vishhvaan Gopalakrishnan, Jennifer L. Cadnum, Jacob G. Scott, Jeff Maltas, Gary An, Curtis J. Donskey, Davis T. Weaver, Julia Pelesko, Jessica A. Scarborough, Tanush Jagdish, Nathan Farrokhian, Benjamin D. McElvany, Emily Dolson, Enze Tian, Geoff Sedor, Emily Ho, Mina N. Dinh, Jinhan Mo, Eshan S. King
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0241734 (2021)
PLoS ONE
PLoS ONE
Personal protective equipment (PPE) is crucially important to the safety of both patients and medical personnel, particularly in the event of an infectious pandemic. As the incidence of Coronavirus Disease 2019 (COVID-19) increases exponentially in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbf053ee409706ac5619679879faf15
https://doaj.org/article/c9cb9eb3a2b1444ea76753df9db95399
https://doaj.org/article/c9cb9eb3a2b1444ea76753df9db95399
Autor:
Masahiro Hitomi, Nikhil Krishnan, Badar J. Kayani, Vishhvaan Gopalakrishnan, Curtis J. Donskey, Michael J. Scott, Julia Pelesko, Eshan S. King, Daniel F. Li, Ian C Charnas, Davis T. Weaver, Jennifer L. Cadnum, Emily Dolson, Jacob G. Scott
Publikováno v:
American Journal of Infection Control
Filtering facepiece respirators (FFR) are critical for protecting essential personnel and limiting the spread of disease. Due to the current COVID-19 pandemic, FFR supplies are dwindling in many health systems, necessitating re-use of potentially con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f7793cb82a3b78f654d34981f9f67b
https://doi.org/10.1101/2020.06.17.20133777
https://doi.org/10.1101/2020.06.17.20133777
Autor:
Gary An, Benjamin D. McElvany, Eshan S. King, Sean A. Diehl, Dena Crozier, Masahiro Hitomi, Vishhvaan Gopalakrishnan, Mina N. Dinh, Davis T. Weaver, Nathan Farrokhian, Kyle J. Card, Jessica A. Scarborough, Jinhan Mo, Julia Pelesko, Jeff Maltas, Jacob G. Scott, Emily Ho, Nikhil Krishnan, Andrew Dhawan, Tanush Jagdish, Ju Li, Geoff Sedor, Gleb Kuzmin, Enze Tian, Emily Dolson
DISCLAIMERThis article does not represent the official recommendation of the Cleveland Clinic or Case Western Reserve University School of Medicine, nor has it yet been peer reviewed. We are releasing it early, pre-peer review, to allow for quick dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dde4acbb206c6aa8b53bae27d5f626d
Autor:
Gui-Lu Long, Linhua Xu, Eshan S. King, Lan Yang, Guangming Zhao, Tao Wang, Sahin Kaya Ozdemir
Publikováno v:
Science Bulletin. 62:875-878
We report Raman lasing and the optical analog of electromagnetically-induced-transparency (EIT) in a whispering-gallery-mode (WGM) microtoroid resonator embedded in a low refractive index polymer matrix together with a tapered fiber coupler. The micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2547db1cb837e2eb9e2fc43e89cf435e
https://doi.org/10.1016/j.scib.2017.05.011
https://doi.org/10.1016/j.scib.2017.05.011
Publikováno v:
ISBI
In single-molecule super-resolution microscopy, engineered point-spread functions (PSFs) are designed to efficiently encode new molecular properties, such as 3D orientation, into complex spatial features captured by a camera. To fully benefit from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e558c6ad6fcb7178f0a58ff8cf6f8156
http://arxiv.org/abs/1901.03898
http://arxiv.org/abs/1901.03898