Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eshagh Dorafshan"'
Autor:
Sandhya Malla, Kanchan Kumari, Carlos A. García-Prieto, Jonatan Caroli, Anna Nordin, Trinh T. T. Phan, Devi Prasad Bhattarai, Carlos Martinez-Gamero, Eshagh Dorafshan, Stephanie Stransky, Damiana Álvarez-Errico, Paulina Avovome Saiki, Weiyi Lai, Cong Lyu, Ludvig Lizana, Jonathan D. Gilthorpe, Hailin Wang, Simone Sidoli, Andre Mateus, Dung-Fang Lee, Claudio Cantù, Manel Esteller, Andrea Mattevi, Angel-Carlos Roman, Francesca Aguilo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Lysine-specific histone demethylase 1 (LSD1), which demethylates mono- or di- methylated histone H3 on lysine 4 (H3K4me1/2), is essential for early embryogenesis and development. Here we show that LSD1 is dispensable for mouse embryonic stem
Externí odkaz:
https://doaj.org/article/2d6f847ecfc84532b688deb0fc0250d8
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3801-3812 (2019)
Antagonistic functions of Polycomb and Trithorax proteins are essential for proper development of all metazoans. While the Polycomb proteins maintain the repressed state of many key developmental genes, the Trithorax proteins ensure that these genes
Externí odkaz:
https://doaj.org/article/3569fbd5cec24931aed71bb5c9223888
Publikováno v:
Science Advances. 7
In Drosophila, two chromosomes require special mechanisms to balance their transcriptional output to the rest of the genome. These are the male-specific lethal complex targeting the male X-chromosome, and Painting of fourth targeting chromosome 4. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f618d4a94bc61db32551caf5afb11af0
https://doi.org/10.1126/sciadv.abh4390
https://doi.org/10.1126/sciadv.abh4390
Publikováno v:
Nucleus. 8:496-505
Polycomb Group (PcG) proteins epigenetically repress key developmental genes and thereby control alternative cell fates. PcG proteins act as complexes that can modify histones and these histone modifications play a role in transmitting the memory of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5f8eabd2947dd4b1a9ed05ee62a722
https://doi.org/10.1080/19491034.2017.1363136
https://doi.org/10.1080/19491034.2017.1363136
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3801-3812 (2019)
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3801-3812 (2019)
Antagonistic functions of Polycomb and Trithorax proteins are essential for proper development of all metazoans. While the Polycomb proteins maintain the repressed state of key developmental genes, the Trithorax proteins ensure that these genes stay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1116ea4c07b600c7dbccb5f7ed89058c
https://doi.org/10.1101/675173
https://doi.org/10.1101/675173
Autor:
Alexander Glotov, Eshagh Dorafshan, Tatyana G. Kahn, Matthias Walther, Yuri B. Schwartz, Gunter Reuter, Mikhail Savitsky
Publikováno v:
EMBO reports. 20
Polycomb repression is critical for metazoan development. Equally important but less studied is the Trithorax system, which safeguards Polycomb target genes from the repression in cells where they have to remain active. It was proposed that the Trith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486593d2a5b89c7418ad45768c5dfd52
https://doi.org/10.15252/embr.201846762
https://doi.org/10.15252/embr.201846762
Autor:
Tatyana G. Kahn, Eshagh Dorafshan, Dorothea Schultheis, Yuri B. Schwartz, Aman Zare, Vincenzo Pirrotta, Ingolf Reim, Per Stenberg
Publikováno v:
Nucleus
Nucleic Acids Research
Nucleic Acids Research
Polycomb Group (PcG) proteins are epigenetic repressors essential for control of development and cell differentiation. They form multiple complexes of which PRC1 and PRC2 are evolutionary conserved and obligatory for repression. The targeting of PRC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc1864b7d3f598ff66b10a881faf7f0
https://doi.org/10.1093/nar/gkw701
https://doi.org/10.1093/nar/gkw701