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Autor:
Meredith Murray, Benjamin J. Doranz, Jada Ingalls, Karan Kampani, Esha Kakkar, Cheryl Paes, Chidananda Sulli, Valery Kotelnikov, Tiffani A. Greene, Joseph Rucker
Publikováno v:
Journal of the American Chemical Society. 131(20)
Epitopes that define the immunodominant regions of conformationally complex integral membrane proteins have been difficult to reliably delineate. Here, a high-throughput approach termed shotgun mutagenesis was used to map the binding epitopes of five