Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eser J, Zerenturk"'
Autor:
Winnie Luu, Eser J. Zerenturk, Ika Kristiana, Martin P. Bucknall, Laura J. Sharpe, Andrew J. Brown
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 3, Pp 410-420 (2014)
The role of signaling in regulating cholesterol homeostasis is gradually becoming more widely recognized. Here, we explored how kinases and phosphorylation sites regulate the activity of the enzyme involved in the final step of cholesterol synthesis,
Externí odkaz:
https://doaj.org/article/0bc11d238d6a4d2ead8669b0473e7254
Autor:
Michael F. Keating, Kaushala S. Jayawardana, Elizabeth J. Tarling, Pengyi Yang, Benjamin L. Parker, Pauline Morand, Matthew J. Watt, Thomas Q. de Aguiar Vallim, Marcus M. Seldin, Matthew L. Miller, Richard T. Lee, Eser J. Zerenturk, Yingying Liu, Ruth C. R. Meex, Aldons J. Lusis, Brian G. Drew, Sarah C. Moody, David E. James, Calvin Pan, Natalie A. Mellett, Peter J. Meikle, Jacquelyn M. Weir, Ross Lazarus, Elise J. Needham, Anna C. Calkin, Bethan L. Clifford, Kang-Yu Peng
Publikováno v:
Nature, vol 567, iss 7747
Dysregulation of lipid homeostasis is a precipitating event in the pathogenesis and progression of hepatosteatosis and metabolic syndrome. These conditions are highly prevalent in developed societies and currently have limited options for diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1bfa88bea79f16882362b6b6eb9b61
https://escholarship.org/uc/item/5090j5bq
https://escholarship.org/uc/item/5090j5bq
Publikováno v:
Journal of molecular endocrinology. 58(4)
Diabetic cardiomyopathy was first defined over four decades ago. It was observed in small post-mortem studies of diabetic patients who suffered from concomitant heart failure despite the absence of hypertension, coronary disease or other likely causa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ca16a182edf704fe6aa6d4204bfa42
https://pubmed.ncbi.nlm.nih.gov/28373293
https://pubmed.ncbi.nlm.nih.gov/28373293
Autor:
Eser J, Zerenturk, Anna C, Calkin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1583
There are many advantages to the use of mice as a model to study the regulation of cholesterol metabolism. Common models of hypercholesterolemia include low-density lipoprotein receptor deficient (LDLR -/-) mice and apolipoprotein E deficient (ApoE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c58cac188b851e6ace5847abc8b6036d
https://pubmed.ncbi.nlm.nih.gov/28205167
https://pubmed.ncbi.nlm.nih.gov/28205167
Autor:
Anna C. Calkin, Eser J. Zerenturk
Publikováno v:
Methods in Molecular Biology ISBN: 9781493968732
There are many advantages to the use of mice as a model to study the regulation of cholesterol metabolism. Common models of hypercholesterolemia include low-density lipoprotein receptor deficient (LDLR -/-) mice and apolipoprotein E deficient (ApoE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb9871a580eae211646c5c83ccc4538
https://doi.org/10.1007/978-1-4939-6875-6_6
https://doi.org/10.1007/978-1-4939-6875-6_6
Autor:
Ika Kristiana, Winnie Luu, Laura J. Sharpe, Martin P. Bucknall, Andrew J. Brown, Eser J. Zerenturk
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 3, Pp 410-420 (2014)
The role of signaling in regulating cholesterol homeostasis is gradually becoming more widely recognized. Here, we explored how kinases and phosphorylation sites regulate the activity of the enzyme involved in the final step of cholesterol synthesis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d1e7df21e7b9799b7ef3f5526c59f7
https://doi.org/10.1194/jlr.m043257
https://doi.org/10.1194/jlr.m043257
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1821:1350-1360
3β-Hydroxysterol Δ24-reductase (DHCR24) catalyzes a final step in cholesterol synthesis, and has been ascribed diverse functions, such as being anti-apoptotic and anti-inflammatory. How this enzyme is regulated transcriptionally by sterols is curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79152dc9940712c3a8754d2b6be9373a
https://doi.org/10.1016/j.bbalip.2012.07.006
https://doi.org/10.1016/j.bbalip.2012.07.006
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f698e01e868c672929b59e5aee37ef6
https://doi.org/10.1096/fasebj.29.1_supplement.568.7
https://doi.org/10.1096/fasebj.29.1_supplement.568.7
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 34, Iss 2, p e00098 (2014)
Bioscience Reports, Vol 34, Iss 2, p e00098 (2014)
Cholesterol synthesis occurs in the ER (endoplasmic reticulum), where most of the cholesterogenic machinery resides. As membrane-bound proteins, their topology is difficult to determine, and thus their structures are largely unknown. To help resolve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a40e7f40722731c24d85dc5c43ea871
http://europepmc.org/articles/PMC3958128
http://europepmc.org/articles/PMC3958128
Publikováno v:
Progress in lipid research. 52(4)
3β-Hydroxysterol Δ(24)-reductase (DHCR24) catalyzes the conversion of desmosterol to cholesterol. This ultimate step of cholesterol biosynthesis appears to be remarkable in its diverse functions and the number of diseases it is implicated in from v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6864c12cdbe0a1f9b2f39f06e1eff646
https://pubmed.ncbi.nlm.nih.gov/24095826
https://pubmed.ncbi.nlm.nih.gov/24095826