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pro vyhledávání: '"Eser, Ünsaldı"'
Autor:
Eser, Unsaldi
Streptomyces clavuligerus is well-known for synthesizing several &beta
lactam antibiotics like cephamycin C which is produced through aspartic acid pathway initiated by aspartokinase (Ask) enzyme encoded by ask. Four different strains were const
lactam antibiotics like cephamycin C which is produced through aspartic acid pathway initiated by aspartokinase (Ask) enzyme encoded by ask. Four different strains were const
Externí odkaz:
http://etd.lib.metu.edu.tr/upload/12612421/index.pdf
Publikováno v:
Synthetic and Systems Biotechnology, Vol 2, Iss 1, Pp 39-48 (2017)
The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random mutagenesis in such strain
Externí odkaz:
https://doaj.org/article/7fbdeae990c742519c365a6327d077d3
Autor:
Dörte Becher, Servet Özcan, Gülay Özcengiz, Birgit Voigt, Aslıhan Kurt-Kızıldoğan, Caner Aktaş, Eser Ünsaldı
Background: Streptomyces clavuligerus is prolific producer of cephamycin C, a medically important antibiotic. In our former study, cephamycin C titer was 2-fold improved by disrupting homoserine dehydrogenase (hom) gene of aspartate pahway in Strepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0da24df72cf7ca03f18f014653f859f
https://aperta.ulakbim.gov.tr/record/232002
https://aperta.ulakbim.gov.tr/record/232002
Autor:
Eser, Ünsaldı, Aslıhan, Kurt-Kızıldoğan, Servet, Özcan, Dörte, Becher, Birgit, Voigt, Caner, Aktaş, Gülay, Özcengiz
Publikováno v:
Protein and peptide letters. 28(2)
Streptomyces clavuligerus is prolific producer of cephamycin C, a medically important antibiotic. In our former study, cephamycin C titer was 2-fold improved by disrupting homoserine dehydrogenase (hom) gene of aspartate pahway in Streptomyces clavul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a0cb11b33698b856eeebec15e19c300
https://pubmed.ncbi.nlm.nih.gov/32707026
https://pubmed.ncbi.nlm.nih.gov/32707026
Ertekin, Ozan/0000-0003-1874-5628; aktas, caner/0000-0001-9911-8559 WOS: 000445196500293 …
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4477d34034d37a548d6e3e5f3c6f39fa
https://doi.org/10.1016/j.nbt.2018.05.1006
https://doi.org/10.1016/j.nbt.2018.05.1006
Publikováno v:
Synthetic and Systems Biotechnology, Vol 2, Iss 1, Pp 39-48 (2017)
Synthetic and Systems Biotechnology
Synthetic and Systems Biotechnology
KURT KIZILDOGAN, ASLIHAN/0000-0002-9323-0993 WOS: 000441177600007 PubMed: 29062960 The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76971fbbf2ffb214c80ec3f7df7b5ec
https://aperta.ulakbim.gov.tr/record/111006
https://aperta.ulakbim.gov.tr/record/111006
Publikováno v:
New Biotechnology. 44:S109
Ertekin, Ozan/0000-0003-1874-5628; aktas, caner/0000-0001-9911-8559 WOS: 000445196500292 …
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a11ccbf073dbaa8617dd2c36c86e5ec
https://doi.org/10.1016/j.nbt.2018.05.1005
https://doi.org/10.1016/j.nbt.2018.05.1005
Publikováno v:
Bioengineered Bugs. 1:191-197
In this study, the effect of homologous multiple copies of the ask gene, which encodes aspartokinase catalyzing the first step of the aspartate pathway, on cephamycin C biosynthesis in S. clavuligerus NRRL 3585 and its hom mutant was investigated. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae404395f62181925a07ac8ecc9a02ff
https://doi.org/10.4161/bbug.1.3.11244
https://doi.org/10.4161/bbug.1.3.11244