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Human metastatic cholangiocarcinoma patient-derived xenografts and tumoroids for preclinical drug evaluation

Autor: Queralt Serra-Camprubí, Helena Verdaguer, Winona Oliveros, Núria Lupión-Garcia, Alba Llop-Guevara, Cristina Molina, Maria Vila-Casadesús, Anthony Turpin, Cindy Neuzillet, Joan Frigola, Jessica Querol, Mariana Yáñez-Bartolomé, Florian Castet, Carles Fabregat-Franco, Carmen Escudero-Iriarte, Marta Escorihuela, Enrique J. Arenas, Cristina Bernadó-Morales, Noemí Haro, Francis J. Giles, Óscar J. Pozo, Josep M. Miquel, Paolo G. Nuciforo, Ana Vivancos, Marta Melé, Violeta Serra, Joaquín Arribas, Josep Tabernero, Sandra Peiró, Teresa Macarulla, Tian V. Tian

Publikováno v: Scientia

Cholangiocarcinoma (CCA) is usually diagnosed at advanced stages, with limited therapeutic options. Preclinical models focused on unresectable metastatic CCA are necessary to develop rational treatments. Pathogenic mutations in IDH1/2, ARID1A/B, BAP1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4099d028372bc61fdb08354764a3e7a4
https://pubmed.ncbi.nlm.nih.gov/36374558

Promising response to lurbinectedin in NUT carcinoma: a case report and review of emerging therapeutic strategies.

Autor: Sánchez Becerra MV; 'Rare Circulating Cells' Translational Platform, Gustave Roussy, Université Paris-Saclay, CNRS UMS3655-INSERM US23 AMMICA, Villejuif; 'Identification of Molecular Predictors and new Targets for Cancer Treatment'. INSERM, U981, Villejuif; Department of Cancer Medicine, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Escudero Iriarte C; Upper GI and Endocrine Tumor Unit, Vall d'Hebron Institute of Oncology, Barcelona, Spain., Travert C; Thoracic Oncology Department, Hôpital Arnaud de Villeneuve-Centre Hospitalier, Universitaire de Montpellier, Montpellier, France., Tian TV; Thoracic Oncology Department, Hôpital Arnaud de Villeneuve-Centre Hospitalier, Universitaire de Montpellier, Montpellier, France., Besse B; 'Rare Circulating Cells' Translational Platform, Gustave Roussy, Université Paris-Saclay, CNRS UMS3655-INSERM US23 AMMICA, Villejuif; 'Identification of Molecular Predictors and new Targets for Cancer Treatment'. INSERM, U981, Villejuif; Department of Cancer Medicine, Gustave Roussy, Université Paris-Saclay, Villejuif, France. Electronic address: benjamin.besse@gustaveroussy.fr.

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2024 Oct 11. Date of Electronic Publication: 2024 Oct 11.