Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Esben S Sørensen"'
Autor:
Stephen A. Fleming, Sarah M. Reyes, Sharon M. Donovan, Olle Hernell, Rulan Jiang, Bo Lönnerdal, Josef Neu, Lawrence Steinman, Esben S. Sørensen, Christina E. West, Ronald Kleinman, John C. Wallingford
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Human milk, due to its unique composition, is the optimal standard for infant nutrition. Osteopontin (OPN) is abundant in human milk but not bovine milk. The addition of bovine milk osteopontin (bmOPN) to formula may replicate OPN’s concentration a
Externí odkaz:
https://doaj.org/article/eed2ae986a36498689796d737fbbeba8
Autor:
Esben S. Sørensen, Brian Christensen
Publikováno v:
Nutrients, Vol 15, Iss 11, p 2423 (2023)
Osteopontin (OPN) is a multifunctional protein found in all vertebrates. OPN is expressed in many different cell types, and is consequently found in most tissues and physiological secretions. OPN is involved in a multitude of biological processes, su
Externí odkaz:
https://doaj.org/article/23c90813a48c4d5dbb0d3c8ac063e107
Autor:
Brian Christensen, Nanna R. Nielsen, Marie R. Sørensen, Lotte N. Jacobsen, Marie S. Ostenfeld, Esben S. Sørensen
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 893 (2023)
Osteopontin (OPN) is a bioactive integrin-binding protein found in high concentrations in milk, where it is present both as a full-length protein and as several N-terminally derived fragments. OPN resists gastric digestion, and via interaction with r
Externí odkaz:
https://doaj.org/article/07c66afda3c64c58a438d6a3d98022e7
Autor:
Brian Christensen, Albert J. Buitenhuis, Lotte N. Jacobsen, Marie S. Ostenfeld, Esben S. Sørensen
Publikováno v:
Nutrients, Vol 15, Iss 5, p 1166 (2023)
Osteopontin (OPN) is a multifunctional protein abundantly present in human milk, whereas the concentration is significantly lower in bovine milk. Human and bovine milk OPN are structurally similar and both proteins resist gastric digestion and reach
Externí odkaz:
https://doaj.org/article/677abec239e4475bb4bc9efa25d98083
Autor:
Stacyann Bailey, Grazyna E Sroga, Betty Hoac, Orestis L Katsamenis, Zehai Wang, Nikolaos Bouropoulos, Marc D McKee, Esben S Sørensen, Philipp J Thurner, Deepak Vashishth
Publikováno v:
eLife, Vol 9 (2020)
Protein phosphorylation, critical for cellular regulatory mechanisms, is implicated in various diseases. However, it remains unknown whether heterogeneity in phosphorylation of key structural proteins alters tissue integrity and organ function. Here,
Externí odkaz:
https://doaj.org/article/93fc932c9bd84bb49dd5fb7d47765f13
Autor:
Brian Christensen, Gitte N Schytte, Carsten Scavenius, Jan J Enghild, Marc D McKee, Esben S Sørensen
Publikováno v:
JBMR Plus, Vol 4, Iss 8, Pp n/a-n/a (2020)
ABSTRACT Matrix extracellular phosphoglycoprotein (MEPE) is expressed in bone and teeth where it has multiple functions. The C‐terminus of MEPE contains a mineral‐binding, acidic serine‐ and aspartate‐rich motif (ASARM) that is also present i
Externí odkaz:
https://doaj.org/article/e20ebaf5192043908ab233ad33899d50
Autor:
Matthias Kuhlmann, Jonas B.R. Hamming, Anders Voldum, Georgia Tsakiridou, Maja T. Larsen, Julie S. Schmøkel, Emil Sohn, Konrad Bienk, David Schaffert, Esben S. Sørensen, Jesper Wengel, Daniel M. Dupont, Kenneth A. Howard
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 284-293 (2017)
The long blood circulatory property of human serum albumin, due to engagement with the cellular recycling neonatal Fc receptor (FcRn), is an attractive drug half-life extension enabling technology. This work describes a novel site-specific albumin do
Externí odkaz:
https://doaj.org/article/51d4e0deff5046be96587b3e4baa4f58
Autor:
Brian Christensen, Andrea E. Toth, Simone S. E. Nielsen, Carsten Scavenius, Steen V. Petersen, Jan J. Enghild, Jan T. Rasmussen, Morten S. Nielsen, Esben S. Sørensen
Publikováno v:
Nutrients, Vol 12, Iss 10, p 3157 (2020)
The effect of food components on brain growth and development has attracted increasing attention. Milk has been shown to contain peptides that deliver important signals to the brains of neonates and infants. In order to reach the brain, milk peptides
Externí odkaz:
https://doaj.org/article/6013432a09cc464f983220d7edfad8c0
Autor:
Esben S. Sørensen, Grum Gebreyesus, Bart Buitenhuis, Lotte Bach Larsen, Christian W. Heegaard, Mette Krogh Larsen, Nina Aagaard Poulsen
Publikováno v:
Gebreyesus, G, Poulsen, N A, Larsen, M K, Larsen, L B, Sørensen, E S, Würtz Heegaard, C & Buitenhuis, A J 2021, ' Vitamin B12 and transcobalamin in bovine milk : Genetic variation and genome-wide association with loci along the genome ', JDS Communications, vol. 2, no. 3, pp. 127-131 . https://doi.org/10.3168/jdsc.2020-0048
In human nutrition, bovine milk is an essential source of bioavailable vitamin B12 and B12-binding proteins, including transcobalamin. In this study, we estimated genetic parameters for milk content of vitamin B12 and transcobalamin using milk sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb1376b9f1daee284348f3f4ad6b7fd
https://doi.org/10.3168/jdsc.2020-0048
https://doi.org/10.3168/jdsc.2020-0048
Autor:
Jan J. Enghild, Esben S. Sørensen, Ida Bregenov, Carsten Scavenius, Gitte N Schytte, Katarzyna Kjøge, Brian Christensen, Steen V. Petersen
Publikováno v:
Schytte, G N, Christensen, B, Bregenov, I, Kjøge, K, Scavenius, C, Petersen, S V, Enghild, J J & Sørensen, E S 2020, ' FAM20C phosphorylation of the RGDSVVYGLR motif in osteopontin inhibits interaction with the αvβ3 integrin ', Journal of Cellular Biochemistry, vol. 121, no. 12, pp. 4809-4818 . https://doi.org/10.1002/jcb.29708
Osteopontin (OPN) is a ubiquitously expressed, multifunctional, and highly phosphorylated protein. OPN contains two neighboring integrin-binding motifs, RGD and SVVYGLR, which mediate interaction with cells. Phosphorylation and proteolytic processing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e2a04a8dfddfc1e7221fa3cc9022d0
https://doi.org/10.1002/jcb.29708
https://doi.org/10.1002/jcb.29708