Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Esben N. Flindt"'
Autor:
Lise Madsen, Michéle Guerre-Millo, Esben N. Flindt, Kjetil Berge, Karl Johan Tronstad, Elin Bergene, Elena Sebokova, Arild C. Rustan, Jørgen Jensen, Susanne Mandrup, Karsten Kristiansen, Iwar Klimes, Bart Staels, Rolf K. Berge
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 5, Pp 742-750 (2002)
Tetradecylthioacetic acid (TTA) is a non-β-oxidizable fatty acid analog, which potently regulates lipid homeostasis. Here we evaluate the ability of TTA to prevent diet-induced and genetically determined adiposity and insulin resistance. In Wistar r
Externí odkaz:
https://doaj.org/article/dfe2696cefa447fb82432d6583837b6b
Autor:
Jens S. Andersen, Esben N. Flindt, Karsten Kristiansen, Lene Aarenstrup, Morten Kirkegaard, Kristian Otkjaer
Publikováno v:
Aarenstrup, L, Flindt, E N, Otkjaer, K, Kirkegaard, M, Andersen, J S & Kristiansen, K 2008, ' HDAC Activity Is Required for p65/RelA-Dependent Repression of PPARdelta-Mediated Transactivation in Human Keratinocytes ', Journal of Investigative Dermatology, vol. 128, pp. 1095-1106 . https://doi.org/10.1038/sj.jid.5701146
Aarenstrup, L, Flindt, E N, Otkjaer, K, Kirkegaard, M, Andersen, J S & Kristiansen, K 2007, ' HDAC activity is required for p65/RelA-dependent repression of PPARdelta-mediated transactivation in human keratinocytes ', Journal of Investigative Dermatology, vol. 128, no. 5, pp. 1095-106 . https://doi.org/10.1038/sj.jid.5701146
Aarenstrup, L, Flindt, E N, Otkjaer, K, Kirkegaard, M, Andersen, J S & Kristiansen, K 2007, ' HDAC activity is required for p65/RelA-dependent repression of PPARdelta-mediated transactivation in human keratinocytes ', Journal of Investigative Dermatology, vol. 128, no. 5, pp. 1095-106 . https://doi.org/10.1038/sj.jid.5701146
Peroxisome proliferator-activated receptors (PPARs) play a key role in differentiation, inflammation, migration, and survival of epidermal keratinocytes. The NF-kappaB has long been known to play pivotal roles in immune and inflammatory responses, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f4ef1bd7cad268faad7c164c88e4e0
https://doi.org/10.1038/sj.jid.5701146
https://doi.org/10.1038/sj.jid.5701146
Autor:
Claus Johansen, Lars Iversen, Majken Westergaard, Karsten Kristiansen, Knud Kragballe, Jeanette Henningsen, Esben N. Flindt
Publikováno v:
Journal of Investigative Dermatology. 124(6):1284-1292
Nuclear factor-kappaB (NF-kappaB) is an inducible nuclear transcription factor regulating a range of cellular processes. An imbalance of the DNA binding activity of NF-kappaB may, therefore, be part of the pathophysiological mechanisms in psoriasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433a6a8a279c6d82f30b0551bc540e8d
Autor:
Jørgen Jensen, Iwar Klimes, Karl Johan Tronstad, Elena Šeböková, Esben N. Flindt, Elin Bergene, Karsten Kristiansen, Kjetil Berge, Arild C. Rustan, Bart Staels, Michèle Guerre-Millo, Susanne Mandrup, Lise Madsen, Rolf K. Berge
Publikováno v:
Scopus-Elsevier
Madsen, L, Guerre-Millo, M, Flindt, E N, Berge, K, Tronstad, K J, Bergene, E, Sebokova, E, Rustan, A C, Jensen, J, Mandrup, S, Kristiansen, K, Klimes, I, Staels, B & Berge, R K 2002, ' Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance. ', Journal of Lipid Research, vol. 43, no. 5, pp. 742-750 .
ResearcherID
Europe PubMed Central
Journal of Lipid Research, Vol 43, Iss 5, Pp 742-750 (2002)
University of Southern Denmark
Madsen, L, Guerre-Millo, M, Flindt, E N, Berge, K, Tronstad, K J, Bergene, E, Sebokova, E, Rustan, A C, Jensen, J, Mandrup, S, Kristiansen, K, Klimes, I, Staels, B & Berge, R K 2002, ' Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance. ', Journal of Lipid Research, vol. 43, no. 5, pp. 742-750 .
ResearcherID
Europe PubMed Central
Journal of Lipid Research, Vol 43, Iss 5, Pp 742-750 (2002)
University of Southern Denmark
Tetradecylthioacetic acid (TTA) is a non- � -oxi- dizable fatty acid analog, which potently regulates lipid ho- meostasis. Here we evaluate the ability of TTA to prevent diet-induced and genetically determined adiposity and insu- lin resistance. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a728d591b427153383d6ccfa11a5d9
https://doi.org/10.1016/s0022-2275(20)30116-4
https://doi.org/10.1016/s0022-2275(20)30116-4
Publikováno v:
Kronstad, K J, Berge, K, Flindt, E N, Kristiansen, K & Berge, R 2001, ' Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth ', Lipids, vol. 36, pp. 305-13 . https://doi.org/10.1007/s11745-001-0722-8
Scopus-Elsevier
Scopus-Elsevier
Antiproliferative properties of molecular regulators of lipid metabolism have been increasingly studied during recent years. Discussion is ongoing concerning optimal treatment conditions and assays used for monitoring proliferation and cytotoxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31fee3ac873bc9971f928469fa2e5dd
https://doi.org/10.1007/s11745-001-0722-8
https://doi.org/10.1007/s11745-001-0722-8
Autor:
Thomas Høj Rasmussen, Hongbin Zhang, Esben N. Flindt, Rasmus Koefoed Petersen, Jacob B. Hansen, Karsten Kristiansen
Publikováno v:
Journal of Biological Chemistry. 276:3175-3182
The peroxisome proliferator-activated receptor gamma (PPARgamma) is a key regulator of terminal adipocyte differentiation. PPARdelta is expressed in preadipocytes, but the importance of this PPAR subtype in adipogenesis has been a matter of debate. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be99e6556a1e0e93ba7f164476fff3cf
https://doi.org/10.1074/jbc.m005567200
https://doi.org/10.1074/jbc.m005567200
Autor:
Olivier Taboureau, Tudor I. Oprea, Si Brask Sonne, Esben N. Flindt, Karsten Kristiansen, Thomas E. Nielsen, Svava Ósk Jónsdóttir, Rasmus K. Petersen, Irene Kouskoumvekaki, Filip Fratev
Publikováno v:
Journal of chemical information and modeling. 53(4)
Full agonists to the peroxisome proliferator-activated receptor (PPAR)γ, such as Rosiglitazone, have been associated with a series of undesired side effects, such as weight gain, fluid retention, cardiac hypertrophy, and hepatotoxicity. Nevertheless
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea59b84cbc688fcc60e476dd9975351
https://pubmed.ncbi.nlm.nih.gov/23432662
https://pubmed.ncbi.nlm.nih.gov/23432662
Autor:
Rolf K. Berge, Kjetil Berge, Esben N. Flindt, Karsten Kristiansen, Lise Madsen, Karl Johan Tronstad, Thomas Høj Rasmussen
Publikováno v:
Carcinogenesis. 22(11)
The peroxisome proliferator-activated receptors (PPARs) are transcription factors involved in fatty acid metabolism and energy homeostasis. The PPARs also play crucial roles in the control of cellular growth and differentiation. Especially, the recen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15b82a4b08cfc2a6d717ba2dce004fb
https://pubmed.ncbi.nlm.nih.gov/11698335
https://pubmed.ncbi.nlm.nih.gov/11698335
Autor:
Irene Kouskoumvekaki, RasmusK. Petersen, Filip Fratev, Olivier Taboureau, Thomas E. Nielsen, TudorI. Oprea, Si B. Sonne, Esben N. Flindt, SvavaÓsk Jónsdóttir, Karsten Kristiansen
Publikováno v:
Journal of Chemical Information & Modeling; Apr2013, Vol. 53 Issue 4, p923-937, 15p
Autor:
Patrick Markt, Rasmus K. Petersen, Esben N. Flindt, Karsten Kristiansen, Johannes Kirchmair, Gudrun Spitzer, Simona Distinto, Daniela Schuster, Gerhard Wolber, Christian Laggner, Thierry Langer
Publikováno v:
Journal of Medicinal Chemistry; Oct2008, Vol. 51 Issue 20, p6303-6317, 15p