Leveraging decagonal in-silico strategies for uncovering IL-6 inhibitors with precision

Autor: Krishna Swaroop, Akey, Krishnan Namboori, P.K., Esakkimuthukumar, M., Praveen, T.K., Nagarjuna, Palathoti, Patnaik, Sunil Kumar, Selvaraj, Jubie

Publikováno v: In Computers in Biology and Medicine September 2023 163

Dual Modulation of IL-6 Pathway by Flavonoid Metal Complex as Immune Boosters for SARS-CoV-2 Therapy

Autor: Akey Krishna Swaroop, Esakkimuthukumar M, Patnaik S.K, Vasanth P, Jeyaprakash M.R, Jawahar N, Jubie S

Publikováno v: ECS Transactions. 107:9771-9779

It is observed that Cytokine Release Syndrome (CRS) is one of the major causes of the death of several COVID-19 patients. Though several cytokines are involved in CRS, IL-6 modulation plays a major role. We aim to develop new flavonoid metal complexe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::83e30d3870fd02b5175d278cbfa0800b
https://doi.org/10.1149/10701.9771ecst

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"In-silico Design and Development of Novel Hydroxyurea Lipid Drug Conjugates for Breast Cancer Therapy Targeting PI3K/AKT/mTOR Pathway".

Autor: Dharmaraj S; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India., Swaroop AK; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India., Esakkimuthukumar M; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India., Negi P; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India., Jubie S; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India.

Publikováno v: Drug research [Drug Res (Stuttg)] 2024 Jan; Vol. 74 (1), pp. 32-41. Date of Electronic Publication: 2024 Jan 11.