Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Esa T. Jarvi"'
Autor:
Christian T. Farrar, Donald P. Matthews, Guixue Yu, Wilfred A. van der Donk, Robert G. Griffin, JoAnne Stubbe, James R. McCarthy, Gary J. Gerfen, Esa T. Jarvi
Publikováno v:
Journal of the American Chemical Society. 120:3823-3835
Ribonucleotide reductase (RDPR) from E. coli catalyzes the conversion of nucleotides to deoxynucleotides and contains an unusual tyrosyl radical−diferric cluster cofactor. (E)-2‘-Fluoromethylene-2‘-deoxycytidine 5‘-diphosphate [(E)-1] obtaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c259a72a2b99fe3abc2a6ccda1e114e
https://doi.org/10.1021/ja972166e
https://doi.org/10.1021/ja972166e
Autor:
D J Silva, Guixue Yu, W. A. Van Der Donk, R J Resvick, D P Matthews, E Wagner, JoAnne Stubbe, Esa T. Jarvi, James R. McCarthy
Publikováno v:
Biochemistry. 35:8381-8391
Ribonucleotide reductase (RDPR) from Escherichia coli catalyzes the conversion of nucleotides to deoxynucleotides and is composed of two homodimeric subunits: R1 and R2. (E)- and (Z)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate (FMCDP) are time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29d2001bb7e0f41718601565b72ae18
https://doi.org/10.1021/bi960190j
https://doi.org/10.1021/bi960190j
Autor:
James R. McCarthy, Esa T. Jarvi
Publikováno v:
Nucleosides and Nucleotides. 13:585-598
The first synthesis of allenic nucleosides derived from natural ribonucleosides is reported. 2′-Deoxy-2′-(ethenylidene)cytidine (8) and 2′-deoxy-2′-(ethenylidine)adenosine (21) were prepared by a modification of the method developed by Tsuji
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3e4712c923cfa03dbab0025f60cbe96
https://doi.org/10.1080/15257779408013264
https://doi.org/10.1080/15257779408013264
Publikováno v:
Tetrahedron Letters. 34:3057-3060
A new method for the electrophilic fluorination of vinyl stannanes using commercially available 1-chloromethyl-4-fluoro-1,4- diazoniabicyclo[2.2.2]octane bis-(tetrafluoroborate) (1) has been developed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de25efd9c29577c31752b8478e4d0340
https://doi.org/10.1016/s0040-4039(00)93378-1
https://doi.org/10.1016/s0040-4039(00)93378-1
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::695517b2c4ca50e421a00665ac204d33
https://doi.org/10.1002/chin.199217244
https://doi.org/10.1002/chin.199217244
Autor:
Prasad S. Sunkara, Nellikunja J. Prakash, Philippe Bey, Donald P. Matthews, Terry L. Bowlin, James R. McCarthy, Edwards Michael L, Esa T. Jarvi, Shujaath Mehdi
Publikováno v:
ChemInform. 22
The design and synthesis of (E)- and (Z)-5'-fluoro-4',5'-didehydro-5'-deoxyadenosine (6 and 13, respectively), a new class of mechanism-based inhibitors of S-adenosyl-L-homocysteine (SAH) hydrolase, is described. A number of analogues of 6 and 13 wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0f68b368c6bb63a0b68317b72347c67
https://doi.org/10.1002/chin.199138268
https://doi.org/10.1002/chin.199138268
Publikováno v:
ChemInform. 22
Difluoromethyldiphenylphosphine oxide ( 5 ) was synthesized from chlorodifluoromethane and diphenylphosphine oxide. Reaction of 5 with a variety of ketones and aldehydes gave 1,1-difluoroolefins. Monofluoromethyldiphenylphosphine oxide ( 7 ) was also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e5b64da9d7a30345cd85f00fe252107
https://doi.org/10.1002/chin.199140184
https://doi.org/10.1002/chin.199140184
Publikováno v:
ChemInform. 22
The carbanion of diethyl 1-fluoro-1-(phenylsulfonyl)methanephosphonate ( 7 ), generated in situ from fluoromethyl phenyl sulfone ( 3 ) undergoes the Horner-Wittig reaction with aldehydes and ketones to yield α-fluoro-α,β-unsaturated sulfones ( 8 )
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84daca6264a9234693820017a94337de
https://doi.org/10.1002/chin.199141114
https://doi.org/10.1002/chin.199141114
Publikováno v:
ChemInform. 24
A new method for the electrophilic fluorination of vinyl stannanes using commercially available 1-chloromethyl-4-fluoro-1,4- diazoniabicyclo[2.2.2]octane bis-(tetrafluoroborate) (1) has been developed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ebdcc1efaa6d34f43844fef92769db5
https://doi.org/10.1002/chin.199340128
https://doi.org/10.1002/chin.199340128
Autor:
James R. McCarthy, Esa T. Jarvi
Publikováno v:
ChemInform. 26
The first synthesis of allenic nucleosides derived from natural ribonucleosides is reported. 2′-Deoxy-2′-(ethenylidene)cytidine (8) and 2′-deoxy-2′-(ethenylidine)adenosine (21) were prepared by a modification of the method developed by Tsuji
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::259a76e11ef8fafe1666ba69ccdf403a
https://doi.org/10.1002/chin.199502194
https://doi.org/10.1002/chin.199502194