Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Esa R, Korpi"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Medications used for the treatment of diseases also affect oral health. We investigated how having/not having periodontitis at baseline in 1985 was associated with purchases of medicines in the long term. The study paradigm is in the oral health-syst
Externí odkaz:
https://doaj.org/article/dd2a419d43de4cdf83ca5a6c02ed8a9d
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
In the brain, extrasynaptically expressed ionotropic, δ subunit-containing γ-aminobutyric acid A-type receptors (δ-GABAARs) have been implicated in drug effects at both neuronal and behavioral levels. These alterations are supposed to be caused vi
Externí odkaz:
https://doaj.org/article/520e0be314fc486ba397645b75e4c743
Autor:
Milo Grotell, Bjørnar den Hollander, Aaro Jalkanen, Essi Törrönen, Jouni Ihalainen, Elena de Miguel, Mateusz Dudek, Mikko I. Kettunen, Petri Hyytiä, Markus M. Forsberg, Esko Kankuri, Esa R. Korpi
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Mephedrone (4-MMC), despite its illegal status, is still a widely used psychoactive substance. Its effects closely mimic those of the classical stimulant drug methamphetamine (METH). Recent research suggests that unlike METH, 4-MMC is not neurotoxic
Externí odkaz:
https://doaj.org/article/a8c218f928c34b7cad371de400fd6571
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
While interest in psychedelic drugs in the fields of psychiatry and neuroscience has re-emerged in recent last decades, the general understanding of the effects of these drugs remains deficient. In particular, there are gaps in knowledge on executive
Externí odkaz:
https://doaj.org/article/17ec6fd46ebe47eab8b598c68f163757
Autor:
Elina Nagaeva, Ivan Zubarev, Carolina Bengtsson Gonzales, Mikko Forss, Kasra Nikouei, Elena de Miguel, Lauri Elsilä, Anni-Maija Linden, Jens Hjerling-Leffler, George J Augustine, Esa R Korpi
Publikováno v:
eLife, Vol 9 (2020)
The cellular architecture of the ventral tegmental area (VTA), the main hub of the brain reward system, remains only partially characterized. To extend the characterization to inhibitory neurons, we have identified three distinct subtypes of somatost
Externí odkaz:
https://doaj.org/article/52b46d9c58a14a8587f7ac245893a9d1
Autor:
Shamsiiat Abdurakhmanova, Milo Grotell, Jenna Kauhanen, Anni-Maija Linden, Esa R. Korpi, Pertti Panula
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Histamine/gamma-aminobutyric acid (GABA) neurons of posterior hypothalamus send wide projections to many brain areas and participate in stabilizing the wake state. Recent research has suggested that GABA released from the histamine/GABA neurons acts
Externí odkaz:
https://doaj.org/article/5a7c750c7b884ba288b1a72b3f66c625
Autor:
Elena de Miguel, Olga Vekovischeva, Lauri V. Elsilä, Anne Panhelainen, Esko Kankuri, Teemu Aitta-aho, Esa R. Korpi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
THIP (gaboxadol), a superagonist of the δ subunit-containing extrasynaptic GABAA receptors, produces persistent neuroplasticity in dopamine (DA) neurons of the ventral tegmental area (VTA), similarly to rewarding drugs of abuse. However, unlike them
Externí odkaz:
https://doaj.org/article/c346a2c99ea1403190559a7393deab96
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Gene-targeted mice with deficient AMPA receptor GluA1 subunits (Gria1-/- mice) show robust hyperlocomotion in a novel environment, suggesting them to constitute a model for hyperactivity disorders such as mania, schizophrenia and attention deficit hy
Externí odkaz:
https://doaj.org/article/e8cb5cd487d1483d8d649c8ce563beaa
Autor:
Elina Nagaeva, Annika Schäfer, Anni-Maija Linden, Lauri V. Elsilä, Maria Ryazantseva, Juzoh Umemori, Ksenia Egorova, Esa R. Korpi
Expanding knowledge about the cellular composition of subcortical brain regions demonstrates large heterogeneity and differences from the cortical architecture. Recently, we described three subtypes of somatostatin-expressing (Sst) neurons in the mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15408b5b8e4f0d7a7274258cede83efc
https://doi.org/10.1101/2023.01.06.522982
https://doi.org/10.1101/2023.01.06.522982
Background: Psychedelics, like lysergic acid diethylamide (LSD), are again being studied as potential therapies for many neuropsychiatric disorders, including addictions. At the same time, the acute effects of psychedelics on rewarding behaviours hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc404dc5a2ce90b8625d40f1c30869c3
http://hdl.handle.net/10138/346089
http://hdl.handle.net/10138/346089