Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Erzsebet Polyak"'
Autor:
Daniel M. Tremmel, Sara Dutton Sackett, Austin K. Feeney, Samantha A. Mitchell, Michael D. Schaid, Erzsebet Polyak, Peter J. Chlebeck, Sakar Gupta, Michelle E. Kimple, Luis A. Fernandez, Jon S. Odorico
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Extracellular matrix (ECM) plays a multitude of roles, including supporting cells through structural and biochemical interactions. ECM is damaged in the process of isolating human islets for clinical transplantation and basic research. A pla
Externí odkaz:
https://doaj.org/article/d36d1f09e52b4c64aca1fbdc9b86197e
Autor:
Lauren Anton, Ann DeVine, Erzsebet Polyak, Anthony Olarerin-George, Amy G. Brown, Marni J. Falk, Michal A. Elovitz
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Preeclampsia is associated with first trimester placental dysfunction. miR-210, a small non-coding RNA, is increased in the preeclamptic placenta. The effects of elevated miR-210 on placental function remain unclear. The objectives of this study were
Externí odkaz:
https://doaj.org/article/c806569c0f524865aa399ef75ec565a9
Autor:
Zhe Zhang, Mai Tsukikawa, Min Peng, Erzsebet Polyak, Eiko Nakamaru-Ogiso, Julian Ostrovsky, Shana McCormack, Emily Place, Colleen Clarke, Gail Reiner, Elizabeth McCormick, Eric Rappaport, Richard Haas, Joseph A Baur, Marni J Falk
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69282 (2013)
Primary mitochondrial respiratory chain (RC) diseases are heterogeneous in etiology and manifestations but collectively impair cellular energy metabolism. Mechanism(s) by which RC dysfunction causes global cellular sequelae are poorly understood. To
Externí odkaz:
https://doaj.org/article/c2e03b712d594c12b237fdd41b0d9428
Autor:
Marni J Falk, Julie R Rosenjack, Erzsebet Polyak, Wichit Suthammarak, Zhongxue Chen, Phil G Morgan, Margaret M Sedensky
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6607 (2009)
Complex I dysfunction is a common, heterogeneous cause of human mitochondrial disease having poorly understood pathogenesis. The extensive conservation of complex I composition between humans and Caenorhabditis elegans permits analysis of individual
Externí odkaz:
https://doaj.org/article/ce4e7d1444054ec687394637313a46a5
Autor:
Min Peng, Marni J Falk, Volker H Haase, Rhonda King, Erzsebet Polyak, Mary Selak, Marc Yudkoff, Wayne W Hancock, Ray Meade, Ryoichi Saiki, Adam L Lunceford, Catherine F Clarke, David L Gasser
Publikováno v:
PLoS Genetics, Vol 4, Iss 4, p e1000061 (2008)
Coenzyme Q (CoQ) is an essential electron carrier in the respiratory chain whose deficiency has been implicated in a wide variety of human mitochondrial disease manifestations. Its multi-step biosynthesis involves production of polyisoprenoid diphosp
Externí odkaz:
https://doaj.org/article/4b0727f4f27f4e6eb1b2ffd376c6dd98
Autor:
Yolanda Ponstein, Luis A. Fernandez, Juan S. Danobeitia, Peter J. Chlebeck, Erzsebet Polyak, Jose R. Torrealba, Casi L. Blanton, Yücel Yankol, Megan L. Springer, Michael J. Eerhart, Jeremy A. Sullivan, Saverio Capuano, Jose A. Reyes, Jennifer Coonen, Myron A. Pozniak, Laura J. Zitur, Anthony M. D'Alessandro, Weixiong Zhong, Edwin Van Amersfoort, William J. Burlingham, Cees van Kooten
Publikováno v:
Transplantation
Transplantation, 106(1), 60-71. LIPPINCOTT WILLIAMS & WILKINS
Transplantation, 106(1), 60-71. LIPPINCOTT WILLIAMS & WILKINS
Background: Complement activation in kidney transplantation is implicated in the pathogenesis of delayed graft function (DGF). This study evaluated the therapeutic efficacy of high-dose recombinant human C1 esterase inhibitor (rhC1INH) to prevent DGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeeda53f63c1477d0615d8ab46b90c68
https://pubmed.ncbi.nlm.nih.gov/34905763
https://pubmed.ncbi.nlm.nih.gov/34905763
Autor:
Daniel M. Tremmel, Sara Dutton Sackett, Austin K. Feeney, Samantha A. Mitchell, Michael D. Schaid, Erzsebet Polyak, Peter J. Chlebeck, Sakar Gupta, Michelle E. Kimple, Luis A. Fernandez, Jon S. Odorico
Publikováno v:
Scientific reports. 12(1)
Extracellular matrix (ECM) plays a multitude of roles, including supporting cells through structural and biochemical interactions. ECM is damaged in the process of isolating human islets for clinical transplantation and basic research. A platform in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a503bf781bf284ce49b4c3135b0e2554
https://pubmed.ncbi.nlm.nih.gov/35504932
https://pubmed.ncbi.nlm.nih.gov/35504932
Autor:
Harry Ischiropoulos, Yi Cheng, Samuel Parry, Laura Sillers, Erzsebet Polyak, Rebecca A. Simmons, Zhe Zhang, Marni J. Falk, Yu-Chin Lien
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7899, p 7899 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7899, p 7899 (2021)
A well-functioning placenta is crucial for normal gestation and regulates the nutrient, gas, and waste exchanges between the maternal and fetal circulations and is an important endocrine organ producing hormones that regulate both the maternal and fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee23301318468e9e7257d6d2afffdfd
http://europepmc.org/articles/PMC8347496
http://europepmc.org/articles/PMC8347496
Autor:
Min Peng, Neal D Mathew, Michael J. Bennett, Richard Lightfoot, Rui Xiao, Chigoziri Konkwo, Manuela Lavorato, Young Joon Kwon, Eiko Nakamaru-Ogiso, Zhe Zhang, Julian Ostrovsky, Marni J. Falk, Christoph Seiler, Sujay Guha, Erzsebet Polyak
Publikováno v:
Hum Mol Genet
Cysteamine bitartrate is a US Food and Drug Administration-approved therapy for nephropathic cystinosis also postulated to enhance glutathione biosynthesis. We hypothesized this antioxidant effect may reduce oxidative stress in primary mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416dd3929e22bc73f5cefa920440f43b
https://doi.org/10.1093/hmg/ddz023
https://doi.org/10.1093/hmg/ddz023
Autor:
Zhe Zhang, Young Joon Kwon, Sujay Guha, Chigoziri Konkwo, Marni J. Falk, Erzsebet Polyak, Christoph Seiler, Rui Xiao, Neal D Mathew, Eiko Nakamaru-Ogiso, Michael J. Bennett, Julian Ostrovsky
Publikováno v:
Human Molecular Genetics
Mitochondrial respiratory chain disorders are empirically managed with variable antioxidant, cofactor and vitamin ‘cocktails’. However, clinical trial validated and approved compounds, or doses, do not exist for any single or combinatorial mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e51adbc1fdb955136895c5b2c9436a6
https://pubmed.ncbi.nlm.nih.gov/33640978
https://pubmed.ncbi.nlm.nih.gov/33640978