Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Erzsébet Lackó"'
Autor:
Kornél Király, Sándor Hosztafi, Ágnes Fehér, Dóra Kocsis, Mihaly Balogh, Anna I. Erdei, András Váradi, Ferenc Zádor, Mahmoud Al-Khrasani, Susanna Fürst, Zoltán S. Zádori, Pál Riba, Sándor Benyhe, Béla Noszál, Erzsébet Lackó
Publikováno v:
European Journal of Pharmacology, 809, 111-121. ELSEVIER SCIENCE BV
Opioid antagonists, naloxone and naltrexone have long been used in clinical practice and research. In addition to their low selectivity, they easily pass through the blood-brain barrier. Quaternization of the amine group in these molecules, (e.g. met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43395ba6ff542e57df33991d74d8b7d6
https://doi.org/10.1016/j.ejphar.2017.05.024
https://doi.org/10.1016/j.ejphar.2017.05.024
Autor:
Shaaban A. Mousa, Pál Riba, Laura Cornic, Péter Ferdinandy, András Váradi, Erzsébet Lackó, Mihaly Balogh, Michael Schäfer, Sándor Hosztafi, Zoltán Giricz, Zoltán Sándor Zádori, Zsuzsanna Helyes, Susanna Fürst, Kata Csekő, Kornél Király, Mahmoud Al-Khrasani
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 359:171-181
Growing data support peripheral opioid antinociceptive effects, particularly in inflammatory pain models. Here, we examined the antinociceptive effects of subcutaneously administered, recently synthesized 14-O-methylmorphine-6-O-sulfate (14-O-MeM6SU)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ba19d02af7252e0942c7d8235f07ed
https://doi.org/10.1124/jpet.116.233551
https://doi.org/10.1124/jpet.116.233551
Autor:
Pál Riba, Mohammed Shaqura, Shaaban A. Mousa, Péter Ferdinandy, Erzsébet Lackó, Baled I. Khalefa, Susanna Fürst, Sándor Hosztafi, Michael Schäfer, Mahmoud Al-Khrasani
Publikováno v:
European Journal of Pharmacology. 713:54-57
This study compared the peripheral analgesic effects of a novel opioid agonist 14- O -methylmorphine-6-O-sulfate (14- O -MeM6SU), to that of non-peptide (morphine, fentanyl) and peptide opioid agonists (Met-enkephalin; met-ENK and β-endorphin; β-EN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69fba67a1467283284ff78d9fb0a911
https://doi.org/10.1016/j.ejphar.2013.04.043
https://doi.org/10.1016/j.ejphar.2013.04.043
Autor:
Ágnes Fehér, Mahmoud Al-Khrasani, Viktória E. Tóth, Zoltán S. Zádori, Lutz Hein, Serena Brancati, Erzsébet Lackó, Klára Gyires, Péter Mátyus
Publikováno v:
European Journal of Pharmacology. 705:61-67
Several lines of evidence suggest that imidazoline receptors mediate various physiological processes. It is rather difficult, however, to distinguish the imidazoline receptor-mediated effects from the alpha₂-adrenoceptor-mediated ones due to the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf12ff3c21238571d3a7267f9d1cd1f1
https://doi.org/10.1016/j.ejphar.2013.02.043
https://doi.org/10.1016/j.ejphar.2013.02.043
Autor:
Julia Timár, Susanna Gyarmati, Apolka Szentirmay, Pál Riba, Mahmoud Al-Khrasani, Kornél Király, N. Lenkey, Susanna Fürst, T. Friedmann, Erzsébet Lackó, Géza Tóth
Publikováno v:
Brain Research Bulletin. 90:66-71
Since the discovery of opioid receptor dimers their possible roles in opioid actions were intensively investigated. Here we suggest a mechanism that may involve the μ-δ opioid heterodimers. The exact role of δ opioid receptors in antinociception a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201a2a9d734ecd5e263656ba7f7a2a3d
https://doi.org/10.1016/j.brainresbull.2012.09.006
https://doi.org/10.1016/j.brainresbull.2012.09.006
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 70:143-150
Sempervivum tectorum L. (houseleek) leaf juice has been known as a traditional herbal remedy. The aim of the present study was the chemical characterization of its phenolic compounds and to develop quantitation methods for its main flavonol glycoside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1891c7d72211591dc2487e65fe695aa3
https://doi.org/10.1016/j.jpba.2012.06.017
https://doi.org/10.1016/j.jpba.2012.06.017
Autor:
Susanna Fürst, Anna Borsodi, Ferenc Zádor, Sándor Benyhe, R. Rapavi, Erzsébet Lackó, Julia Timár, Mahmoud Al-Khrasani, Sándor Hosztafi, András Váradi, Pál Riba, Béla Noszál
Publikováno v:
Current Medicinal Chemistry. 19:4699-4707
The aims of this study were to synthesize 14-O-Methylmorphine-6-O-sulfate (14-O-MeM6SU) and examine its opioid properties (potency, affinity, efficacy) in receptor ligand binding and isolated tissues (mouse vas deferens, MVD and rat vas deferens, RVD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c2529a0d49633f9de2bf3825756266
https://doi.org/10.2174/092986712803306376
https://doi.org/10.2174/092986712803306376
Publikováno v:
Immunology. 119:278-288
It has been known for 15 years that the chicken epidermis contains ATPase+ and major histocompatibility complex class II-positive (MHCII+) dendritic cells. These cells were designated as Langerhans cells but neither their detailed phenotype nor their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56768f09804994f744f23254b743aac
https://doi.org/10.1111/j.1365-2567.2006.02432.x
https://doi.org/10.1111/j.1365-2567.2006.02432.x
Autor:
Zoltán S, Zádori, Ágnes, Fehér, Mahmoud, Al-Khrasani, Erzsébet, Lackó, Viktória E, Tóth, Serena B, Brancati, Lutz, Hein, Péter, Mátyus, Klára, Gyires
Publikováno v:
European journal of pharmacology. 705(1-3)
Several lines of evidence suggest that imidazoline receptors mediate various physiological processes. It is rather difficult, however, to distinguish the imidazoline receptor-mediated effects from the alpha₂-adrenoceptor-mediated ones due to the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63e34ac28186a516b4154f4572f22c42
https://pubmed.ncbi.nlm.nih.gov/23499689
https://pubmed.ncbi.nlm.nih.gov/23499689
Autor:
Kornél Király, Mahmoud Al-Khrasani, Erzsébet Lackó, Shaaban A. Mousa, Michael Schäfer, Susanna Fürst, Pál Riba, Melinda Sobor, Julia Timár
Publikováno v:
Brain research bulletin. 87(2-3)
This study describes the antinociceptive effects of μ-opioid agonists, d-Ala(2),N-Me-Phe(4),Gly(5)-ol-enkephalin (DAMGO) and morphine in a model of rat visceral pain in which nociceptive responses were triggered by 2% acetic acid intraperitoneal (i.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe8e7a59addaa262f399d2c09ed10e6
https://pubmed.ncbi.nlm.nih.gov/22079588
https://pubmed.ncbi.nlm.nih.gov/22079588