Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Eryun Zhang"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-4 (2023)
Resveratrol (REV) is a natural polyphenol with anti-obesity effects. However, the mechanisms remain unclear due to its low bioavailability and the lack of defined membrane-bound or nuclear receptors. Pang and colleagues reported that REV intervention
Externí odkaz:
https://doaj.org/article/d2299b0ead494348a5bbba7667b705be
Autor:
Zhipeng Fang, Mingjie Fan, Dongqiang Yuan, Lihua Jin, Yangmeng Wang, Lili Ding, Senlin Xu, Jui Tu, Eryun Zhang, Xiwei Wu, Zhen Bouman Chen, Wendong Huang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
A hepatic lncRNA Gm19619, which is repressed by vertical sleeve gastrectomy but upregulated by obesity and fasting, regulates gluconeogenesis and lipid metabolism in mice through Foxo1-G6pc/Pck1 and Lepr signaling pathway respectively.
Externí odkaz:
https://doaj.org/article/6e2e1eb73d054ac9931461455e25e4ca
Autor:
Jiawei Zhang, Yichao Gan, Hongzhi Li, Jie Yin, Xin He, Liming Lin, Senlin Xu, Zhipeng Fang, Byung-wook Kim, Lina Gao, Lili Ding, Eryun Zhang, Xiaoxiao Ma, Junfeng Li, Ling Li, Yang Xu, David Horne, Rongzhen Xu, Hua Yu, Ying Gu, Wendong Huang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
CDK2 can drive the proliferation of cancer cells. Here, the authors screened for a non-ATP competitive inhibitor of the CDK2/cylinA complex and find that Homoharringtonine can disrupt the complex and promote the degradation of CDK2.
Externí odkaz:
https://doaj.org/article/ac83cddd29e447fc91fa01e2387d3f72
Autor:
Eryun Zhang, Lihua Jin, Yangmeng Wang, Jui Tu, Ruirong Zheng, Lili Ding, Zhipeng Fang, Mingjie Fan, Ismail Al-Abdullah, Rama Natarajan, Ke Ma, Zhengtao Wang, Arthur D. Riggs, Sarah C. Shuck, Li Yang, Wendong Huang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Mammalian 5′-AMP-activated protein kinase (AMPK) is a nutrient sensor and a therapeutic target for Type 2 Diabetes. Here the authors report that intestinal AMPK modulates brown adipose tissue thermogenesis through anti-microbial peptide controlled
Externí odkaz:
https://doaj.org/article/485d44f0baf04706b6b2590153a90ce8
Autor:
Mingjie Fan, Yangmeng Wang, Lihua Jin, Zhipeng Fang, Jiangling Peng, Jui Tu, Yanjun Liu, Eryun Zhang, Senlin Xu, Xiaoqian Liu, Yuqing Huo, Zhaoli Sun, Xiaojuan Chao, Wen-Xing Ding, Qingfeng Yan, Wendong Huang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 809-826 (2022)
Background & Aims: Alcohol-associated liver disease (AALD) is one of the most common causes of liver injury and failure. Limited knowledge of the mechanisms underlying AALD impedes the development of efficacious therapies. Bile acid (BA) signaling wa
Externí odkaz:
https://doaj.org/article/65cf997ee44144089c920bc96045e39f
Autor:
Lili Ding, Qiaoling Yang, Eryun Zhang, Yangmeng Wang, Siming Sun, Yingbo Yang, Tong Tian, Zhengcai Ju, Linshan Jiang, Xunjiang Wang, Zhengtao Wang, Wendong Huang, Li Yang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1541-1554 (2021)
Obesity and its associated complications are highly related to a current public health crisis around the world. A growing body of evidence has indicated that G-protein coupled bile acid (BA) receptor TGR5 (also known as Gpbar-1) is a potential drug t
Externí odkaz:
https://doaj.org/article/8bad304eba994309a24c07d4af188532
Autor:
Yanjun Liu, Jui Tu, Linsen Shi, Zhipeng Fang, Mingjie Fan, Jianying Zhang, Lili Ding, Yiqiang Chen, Yangmeng Wang, Eryun Zhang, Senlin Xu, Nisha Sharma, Gillece, John D., Reining, Lauren J., Lihua Jin, Wendong Huang
Publikováno v:
Hepatology (02709139); May2024, Vol. 79 Issue 5, p1005-1018, 14p
Publikováno v:
Liver Research, Vol 1, Iss 4, Pp 208-213 (2017)
The rapid worldwide rise in obesity rates over the past few decades imposes an urgent need to develop effective strategies for treating obesity and associated metabolic complications. Bariatric surgical procedures, such as Roux-en-Y gastric bypass (R
Externí odkaz:
https://doaj.org/article/1431ef146ec14c55b6cceb7e212da886
Autor:
Zhengcai Ju, Lin-shan Jiang, Xunjiang Wang, Wendong Huang, Zhengtao Wang, Siming Sun, Eryun Zhang, Lili Ding, Tong Tian, Qiaoling Yang, Li Yang, Yangmeng Wang, Yingbo Yang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1541-1554 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Obesity and its associated complications are highly related to a current public health crisis around the world. A growing body of evidence has indicated that G-protein coupled bile acid (BA) receptor TGR5 (also known as Gpbar-1) is a potential drug t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f45516d038bca9fd9338d0a4c987b9
http://www.sciencedirect.com/science/article/pii/S2211383521001106
http://www.sciencedirect.com/science/article/pii/S2211383521001106
Autor:
ERYUN ZHANG
Publikováno v:
Diabetes. 71
Mammalian 5′-AMP-activated protein kinase (AMPK) is a key nutrient sensor for maintaining cellular energy status and a known therapeutic target for glucose control in type 2 diabetes (T2D) . Despite current understandings of its well-established ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97470fe229e63d98e8dae9ff72588d83
https://doi.org/10.2337/db22-1297-p
https://doi.org/10.2337/db22-1297-p