Zobrazeno 1 - 10
of 752
pro vyhledávání: '"Erwin W Gelfand"'
Autor:
Jordan K Abbott, Sanny K Chan, Morgan MacBeth, James L Crooks, Cathy Hancock, Vijaya Knight, Erwin W Gelfand
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0265852 (2022)
Despite adequate infection prophylaxis, variation in self-reported quality of life (QOL) throughout the intravenous immunoglobulin (IVIG) infusion cycle is a widely reported but infrequently studied phenomenon. To better understand this phenomenon, s
Externí odkaz:
https://doaj.org/article/c6da9797edea469d8b87ef3b802ba001
Autor:
Meiqin Wang, Matthew J Strand, Bruce J Lanser, Carah Santos, Kreso Bendelja, Jennifer Fish, Elizabeth A Esterl, Shigeru Ashino, Jordan K Abbott, Vijaya Knight, Erwin W Gelfand
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233563 (2020)
Activation of the steroidogenic enzyme CYP11A1 was shown to be necessary for the development of peanut-induced intestinal anaphylaxis and IL-13 production in allergic mice. We determined if levels of CYP11A1 in peripheral blood T cells from peanut-al
Externí odkaz:
https://doaj.org/article/9070db838c9e4d61b7a8bd0bf7c36877
Publikováno v:
Allergology International, Vol 57, Iss 4, Pp 291-298 (2008)
Leukotriene B4 (LTB4) is a lipid mediator with potent chemoattractant properties and that is rapidly generated from activated innate immune cells such as neutrophils, macrophages, and mast cells. Elevated levels of LTB4 have been reported in various
Externí odkaz:
https://doaj.org/article/1e99f9af35e341d1a227a7b5589fd000
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97448 (2014)
G1-phase cell cycle defects, such as alterations in cyclin D1 or cyclin-dependent kinase (cdk) levels, are seen in most tumors. For example, increased cyclin D1 and decreased cdk6 levels are seen in many human breast tumors. Overexpression of cdk6 in
Externí odkaz:
https://doaj.org/article/ea926ea5012349f38611fb3c5dda0486
Autor:
Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Angelina M. Santini, Rama Pranadinata, Casey D. Johnson, Matthew D. McGeough, Federico C. Beasley, Ryan Stansfield, Christopher McBride, Lynnie Trzoss, Hal M. Hoffman, Ariel E. Feldstein, Jeffrey A. Stafford, James M. Veal, Gretchen Bain, Erwin W. Gelfand
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The NLRP3 inflammasome is an intracellular, multiprotein complex that promotes the auto-catalytic activation of caspase-1 and the subsequent maturation and secretion of the pro-inflammatory cytokines, IL-1β and IL-18. Persistent activation
Externí odkaz:
https://doaj.org/article/a9366cea20b64379ae3b798f5d428a2d
Autor:
Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Angelina M. Santini, Rama Pranadinata, Casey D. Johnson, Matthew D. McGeough, Federico C. Beasley, Ryan Stansfield, Christopher McBride, Lynnie Trzoss, Hal M. Hoffman, Ariel E. Feldstein, Jeffrey A. Stafford, James M. Veal, Gretchen Bain, Erwin W. Gelfand
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/71601d03ca0a42d8941718d51407d3e9
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Alpha-1 antitrypsin (AAT) is a major serine protease inhibitor. AAT deficiency (AATD) is a genetic disorder characterized by early-onset severe emphysema. In well-selected AATD patients, therapy with plasma-derived AAT (pAAT), “
Externí odkaz:
https://doaj.org/article/9ee8255ff0a541978be194128084f1c0
Autor:
Nathan Rabinovitch, Meaghan J. Jones, Nicole Gladish, Anna V. Faino, Matthew Strand, Alexander M. Morin, Julie MacIsaac, David T. S. Lin, Paul R. Reynolds, Amrit Singh, Erwin W. Gelfand, Michael S. Kobor, Christopher Carlsten
Publikováno v:
Epigenetics, Vol 16, Iss 2, Pp 177-185 (2021)
Air pollution is associated with early declines in lung function and increased levels of asthma-related cysteinyl leukotrienes (CysLT) but a biological pathway linking this rapid response has not been delineated. In this randomized controlled diesel
Externí odkaz:
https://doaj.org/article/de69246eb7144191a962e43961d0a1b0
CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons
Autor:
Xi Zhang, Camille M. Moore, Laura D. Harmacek, Joanne Domenico, Vittobai Rashika Rangaraj, Justin E. Ideozu, Jennifer R. Knapp, Katherine J. Woods, Stephanie Jump, Shuang Jia, Jeremy W. Prokop, Russell Bowler, Martin J. Hessner, Erwin W. Gelfand, Hara Levy
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
Cystic fibrosis (CF) is an inherited disorder caused by biallelic mutations of the CF transmembrane conductance regulator (CFTR) gene. Converging evidence suggests that CF carriers with only 1 defective CFTR copy are at increased risk for CF-related
Externí odkaz:
https://doaj.org/article/a63d56dde4aa4e118ea14046497fc7b7
Autor:
Michaela Schedel, Sonia M. Leach, Matthew J. Strand, Thomas Danhorn, Morgan MacBeth, Anna V. Faino, Anne M. Lynch, Virginia D. Winn, Lindsay L. Munoz, Shannon M. Forsberg, David A. Schwartz, Erwin W. Gelfand, Pia J. Hauk
Publikováno v:
Allergy. 78:244-257
The prevalence of atopic diseases has increased with atopic dermatitis (AD) as the earliest manifestation. We assessed if molecular risk factors in atopic mothers influence their infants' susceptibility to an atopic disease.Pregnant women and their i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8254eb534a2398b441f69c829ee1422
https://doi.org/10.1111/all.15490
https://doi.org/10.1111/all.15490