Zobrazeno 1 - 10
of 2 375
pro vyhledávání: '"Erwin M"'
Publikováno v:
Scandinavian Journal of Work, Environment & Health, Vol 50, Iss 7, Pp 555-566 (2024)
OBJECTIVE: This study evaluated the effectiveness of the promotion of postural shift intervention using a dynamic seat cushion on the 6-month incidence of neck and low-back pain among high-risk office workers. METHODS: In a cluster-randomized control
Externí odkaz:
https://doaj.org/article/a72315a4738446e9b45eac48417935a3
Autor:
Elizabeth Heyes, Anna S. Wilhelmson, Anne Wenzel, Gabriele Manhart, Thomas Eder, Mikkel B. Schuster, Edwin Rzepa, Sachin Pundhir, Teresa D’Altri, Anne-Katrine Frank, Coline Gentil, Jakob Woessmann, Erwin M. Schoof, Manja Meggendorfer, Jürg Schwaller, Torsten Haferlach, Florian Grebien, Bo T. Porse
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The myeloid transcription factor CEBPA is recurrently biallelically mutated (i.e., double mutated; CEBPA DM) in acute myeloid leukemia (AML) with a combination of hypermorphic N-terminal mutations (CEBPA NT), promoting expression of the leuk
Externí odkaz:
https://doaj.org/article/015f842398434c8ab9d3b64437bd9772
Autor:
Valdemaras Petrosius, Pedro Aragon-Fernandez, Nil Üresin, Gergo Kovacs, Teeradon Phlairaharn, Benjamin Furtwängler, Jeff Op De Beeck, Sarah L. Skovbakke, Steffen Goletz, Simon Francis Thomsen, Ulrich auf dem Keller, Kedar N. Natarajan, Bo T. Porse, Erwin M. Schoof
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Single-cell resolution analysis of complex biological tissues is fundamental to capture cell-state heterogeneity and distinct cellular signaling patterns that remain obscured with population-based techniques. The limited amount of material e
Externí odkaz:
https://doaj.org/article/14054e0093804c9391743fbe1ba55ea0
Autor:
Corné AM Roelen, Erwin M Speklé, Birgit I Lissenberg-Witte, Martijn W Heymans, Willem van Rhenen, Frederieke G Schaafsma
Publikováno v:
Scandinavian Journal of Work, Environment & Health, Vol 48, Iss 7, Pp 579-585 (2022)
OBJECTIVE: This study tested and validated an existing tool for its ability to predict the risk of long-term (ie, ≥6 weeks) sickness absence (LTSA) after four days of sick-listing. METHODS: A 9-item tool is completed online on the fourth day of sic
Externí odkaz:
https://doaj.org/article/73e6bcad1aea4e28abbf00c6ac41bf1d
Autor:
Maria Rafaeva, Adina R. D. Jensen, Edward R. Horton, Kamilla W. Zornhagen, Jan E. Strøbech, Lutz Fleischhauer, Alejandro E. Mayorca-Guiliani, Sebastian R. Nielsen, Dina S. Grønseth, Filip Kuś, Erwin M. Schoof, Luis Arnes, Manuel Koch, Hauke Clausen-Schaumann, Valerio Izzi, Raphael Reuten, Janine T. Erler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The desmoplastic reaction observed in many cancers is a hallmark of disease progression and prognosis, particularly in breast and pancreatic cancer. Stromal-derived extracellular matrix (ECM) is significantly altered in desmoplasia, and as such plays
Externí odkaz:
https://doaj.org/article/1b359b8013e44394a924f6031f8d7cb2
Autor:
Laura Louise Lindqvist, Scott A. Jarmusch, Eva C. Sonnenschein, Mikael Lenz Strube, Janie Kim, Maike Wennekers Nielsen, Paul J. Kempen, Erwin M. Schoof, Sheng-Da Zhang, Lone Gram
Publikováno v:
mSphere, Vol 8, Iss 1 (2023)
ABSTRACT In the marine environment, surface-associated bacteria often produce an array of antimicrobial secondary metabolites, which have predominantly been perceived as competition molecules. However, they may also affect other hallmarks of surface-
Externí odkaz:
https://doaj.org/article/3d2f46eddfe04f64be71823e7bc0f9f4
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background This study aimed to quantify the absenteeism costs of knee and hip osteoarthritis in the Netherlands for the Dutch workforce and specific groups of workers. Methods We used a longitudinal, dynamic database from a large occupationa
Externí odkaz:
https://doaj.org/article/0ec8033df43246f491e6996bbdea2def
Autor:
Klaus Rieneck, Karen Koefoed Rasmussen, Erwin M Schoof, Frederik Banch Clausen, Henrietta Holze, Thomas Bergholt, Marianne Hørby Jørgensen, Vibeke Brix Christensen, Runar Almaas, Peter Lüttge Jordal, Marie Locard-Paulet, Kasper Runager, Leif Kofoed Nielsen, Balthasar Clemens Schlotmann, Joachim Lütken Weischenfeldt, Lars Juhl Jensen, Morten Hanefeld Dziegiel
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0286432 (2023)
The prevailing concept is that gestational alloimmune liver disease (GALD) is caused by maternal antibodies targeting a currently unknown antigen on the liver of the fetus. This leads to deposition of complement on the fetal hepatocytes and death of
Externí odkaz:
https://doaj.org/article/6c90ac40f7e14cda8962eef73d907e21
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105806- (2023)
Summary: Wee1-like protein kinase (WEE1) restrains activities of cyclin-dependent kinases (CDKs) in S and G2 phase. Inhibition of WEE1 evokes drastic increase in CDK activity, which perturbs replication dynamics and compromises cell cycle checkpoints
Externí odkaz:
https://doaj.org/article/37a3c2b431144addafffad64e750b3d8
Autor:
Valdemaras Petrosius, Erwin M. Schoof
Publikováno v:
Translational Oncology, Vol 27, Iss , Pp 101556- (2023)
The field of single-cell omics is rapidly progressing. Although DNA and RNA sequencing-based methods have dominated the field to date, global proteome profiling has also entered the main stage. Single-cell proteomics was facilitated by advancements i
Externí odkaz:
https://doaj.org/article/27cc4e9753ae47f09f09a778521f5dbf