Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Erwin K. Chung"'
Autor:
Haikady N. Nagaraja, Yan Yang, Erwin K. Chung, Chin-Man Wang, Ji Yih Chen, Mo Yin Mok, Yee Ling Wu, Huanyu Wang, Denise J. H. C. Yu, C. Yung Yu, Karla Jones, Yu-Lung Lau, Alaaedin Alhomosh, Chak Sing Lau, Charles H. Spencer, Yeong-Jian Jan Wu, Katherine E. Lintner, Bi Zhou
Publikováno v:
Arthritis & Rheumatology. 68:1442-1453
OBJECTIVE Human complement C4 is complex, with multiple layers of diversity. The aims of this study were to elucidate the copy number variations (CNVs) of C4A and C4B in relation to disease risk in systemic lupus erythematosus (SLE), and to compare t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8677bf875a99cd225fa176208117a619
https://doi.org/10.1002/art.39589
https://doi.org/10.1002/art.39589
Autor:
Yan Yang, Yee Ling Wu, Kapil Saxena, Erwin K. Chung, Leena Hiremath, Kathryn J. Kitzmiller, C. Yung Yu, Nazreen Esack, Bi Zhou
Publikováno v:
Molecular Immunology. 46:1289-1303
Inter-individual gene copy-number variations (CNVs) probably afford human populations the flexibility to respond to a variety of environmental challenges, but also lead to differential disease predispositions. We investigated gene CNVs for complement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c17c063e70e57e42a4d1b60f50ef5ea
https://doi.org/10.1016/j.molimm.2008.11.018
https://doi.org/10.1016/j.molimm.2008.11.018
Autor:
Marja-Liisa Lokki, C. Yung Yu, László Romics, Erwin K. Chung, Yan Yang, Sigurdur Bödvarsson, Jenõ Duba, Csaba Szalai, Gudmundur Thorgeirsson, Ágnes Vatay, Bi Zhou, Judith Kramer, Margit Kovács, Gudmundur J. Arason, Carol A. Blanchong, István Karádi, Zoltán Prohászka, George Füst
Publikováno v:
International Immunology. 16:1507-1514
The genetic basis for addiction to tobacco smoking--particularly that of the perception of olfactory stimuli that may be important in reinforcing smoking addiction--is largely unknown. A cluster of genes for olfactory receptors is in close proximity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a687e2ea6f32732d6dca58630e728db1
https://doi.org/10.1093/intimm/dxh152
https://doi.org/10.1093/intimm/dxh152
Publikováno v:
The Journal of Immunology. 173:2803-2814
Although a heterozygous deficiency of either complement component C4A or C4B is common, and each has a frequency of ∼20% in a Caucasian population, complete deficiencies of both C4A and C4B proteins are extremely rare. In this paper the clinical co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af3afb36add392d9b30fa3bba3411be
https://doi.org/10.4049/jimmunol.173.4.2803
https://doi.org/10.4049/jimmunol.173.4.2803
Autor:
Erwin K. Chung, Carol A. Blanchong, C. Yung Yu, Karla N. Jones, Kristi L. Rupert, Robert M. Rennebohm, Yan Yang
Publikováno v:
The American Journal of Human Genetics. 71:810-822
The complex genetics of human complement C4 with unusually frequent variations in the size and number of C4A and C4B, as well as their neighboring genes, in the major histocompatibility complex has been a hurdle for accurate epidemiological studies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1fc4269ea58f3087f7be079f0c4349
https://doi.org/10.1086/342778
https://doi.org/10.1086/342778
Autor:
Kristi L. Rupert, Robert M. Rennebohm, Bi Zhou, Erwin K. Chung, Karla Jones, C. Yung Yu, Juan F. Sotos, William B. Zipf, Carol A. Blanchong
Publikováno v:
Journal of Experimental Medicine. 191:2183-2196
The complement component C4 genes located in the major histocompatibility complex (MHC) class III region exhibit an unusually complex pattern of variations in gene number, gene size, and nucleotide polymorphism. Duplication or deletion of a C4 gene a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51fee5a536b8f801b8989c44ab819668
https://doi.org/10.1084/jem.191.12.2183
https://doi.org/10.1084/jem.191.12.2183
Autor:
Chack Yung Yu, Ji Yih Chen, Yee Ling Wu, Mo Yin Mok, Yeong-Jian Jan Wu, Katherine E. Lintner, Chin-Man Wang, Erwin K. Chung, Yan Yang, Bi Zhou, Huanyu Wang, Denise J.H.C. Yu, Alaaedin Alhomosh, Karla Jones, Charles H. Spencer, Haikady N. Nagaraja, Yu Long Lau, Chak-Sing Lau
Publikováno v:
The Journal of Immunology. 196:193.10-193.10
Human complement C4 is complex with multiple layers of diversity. This study aims to elucidate the copy-number variations (CNVs) of C4A and C4B in disease risk of SLE, and compare the basis of race-specific C4A-deficiency in East-Asians (EA) and Euro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::959979ad20e0a5a7e3a2e67d189052dc
https://doi.org/10.4049/jimmunol.196.supp.193.10
https://doi.org/10.4049/jimmunol.196.supp.193.10
Autor:
Carol A. Blanchong, Csaba Szalai, Yan Yang, Yee Ling Wu, Margit Kovács, Éva Pozsonyi, Bi Zhou, Ádám Fazakas, C. Yung Yu, Erwin K. Chung, Judit Laki, György Füst, Nóra Hosszúfalusi, Katalin Rajczy, Zoltán Prohászka, Petra Kiszel, Ágnes Vatay, Pál Pánczél, Bernadett Blaskó
Publikováno v:
Immunological investigations. 36(3)
Within the human MHC region larger stretches of conserved DNA, called conserved ancestral haplotypes exist. However, many MHC haplotypes contain only fragments of an ancestral haplotype. Little is known, however, on relative distribution of the ances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e464df8a0048ee906aded68fee8426d
https://pubmed.ncbi.nlm.nih.gov/17558713
https://pubmed.ncbi.nlm.nih.gov/17558713
Autor:
Yee Ling Wu, Bi Zhou, Daniel J. Birmingham, Gloria C. Higgins, Yan Yang, Brad H. Rovin, C. Yung Yu, Robert M. Rennebohm, Lee A. Hebert, Haikady N. Nagaraja, Erwin K. Chung
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387322315
The serial changes of serum complement proteins C4 and C3 in SLE were characterized in 33 pediatric SLE patients with defined C4 genotypes. Three distinct groups of C4 protein profiles were observed. The first group was characterized by persistently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cc20b8aa559b4c8e537fb5903274217
https://doi.org/10.1007/0-387-34134-x_16
https://doi.org/10.1007/0-387-34134-x_16
Autor:
Yee-Ling, Wu, Gloria C, Higgins, Robert M, Rennebohm, Erwin K, Chung, Yan, Yang, Bi, Zhou, Haikady N, Nagaraja, Dan J, Birmingham, Brad H, Rovin, Lee A, Hebert, C Yung, Yu
Publikováno v:
Advances in experimental medicine and biology. 586
The serial changes of serum complement proteins C4 and C3 in SLE were characterized in 33 pediatric SLE patients with defined C4 genotypes. Three distinct groups of C4 protein profiles were observed. The first group was characterized by persistently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8b37ff8f686df2b08e11e6bbfd614e7
https://pubmed.ncbi.nlm.nih.gov/16893076
https://pubmed.ncbi.nlm.nih.gov/16893076