Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Erwin J Landon"'
Autor:
Ning Wang, Gerald D Frank, Ronghua Ding, Zhongjia Tan, Amita Rachakonda, Pier Paolo Pandolfi, Takaaki Senbonmatsu, Erwin J Landon, Tadashi Inagami
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35632 (2012)
Pressure overload and prolonged angiotensin II (Ang II) infusion elicit cardiac hypertrophy in Ang II receptor 1 (AT(1)) null mouse, whereas Ang II receptor 2 (AT(2)) gene deletion abolishes the hypertrophic response. The roles and signals of the car
Externí odkaz:
https://doaj.org/article/32c15b54e1cb4800b2ce23088bdabb21
Autor:
Tadashi Inagami, Gerald D. Frank, Ning Wang, Erwin J. Landon, Takaaki Senbonmatsu, Zhe Li, Zhizhuang Joe Zhao, Ronghua Ding
Publikováno v:
Journal of Biological Chemistry. 281:21878-21883
SHP-1 and SHP-2 are two Src homology 2 domain-containing tyrosine phosphatases with major pathological implications in cell growth regulating signaling. They share significant overall sequence identity, but their biological functions are often opposi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2c3ab20e532f606b9e41db6aeb6c7c
https://doi.org/10.1074/jbc.m605018200
https://doi.org/10.1074/jbc.m605018200
Autor:
Edward Price, Takako Saito, Tadashi Inagami, Richard L. Roberts, Hans Imboden, F. Andrew Gaffney, Erwin J. Landon, Otsu Watanabe, Trinita G. Fitzgerald, Takaaki Senbonmatsu
Publikováno v:
The EMBO Journal. 22:6471-6482
We describe a novel signaling mechanism mediated by the G-protein-coupled receptor (GPCR) angiotensin II (Ang II) type 2 receptor (AT(2)). Yeast two-hybrid studies and affinity column binding assay show that the isolated AT(2) C-terminus binds to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb64b3cfe619cacfb171a6680d58869
https://doi.org/10.1093/emboj/cdg637
https://doi.org/10.1093/emboj/cdg637
Publikováno v:
Journal of Biological Chemistry. 277:5441-5447
Endothelial cell spreading, migration, and morphogenesis are essential for angiogenesis, the formation of new blood vessels. In the present study, we explored roles of tyrosine kinase Pyk2 in angiogenesis of pulmonary endothelial cells. We found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec75c7864385bdf0ef037f8a54657169
https://doi.org/10.1074/jbc.m110673200
https://doi.org/10.1074/jbc.m110673200
Publikováno v:
Journal of Biological Chemistry. 276:15761-15767
We recently reported the calcium-dependent activation of tyrosine kinase Pyk2 by angiotensin II (Ang II) in pulmonary vein endothelial cells (PVEC). Since Pyk2 has no calcium binding domain, and neither Ca(2+) nor Ca(2+)/calmodulin directly activates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15afcd689517232138d85f77992a4fa3
https://doi.org/10.1074/jbc.m009165200
https://doi.org/10.1074/jbc.m009165200
Autor:
Masaaki Tamura, Alan Steimle, Miles A. Tanner, Paul R. Myers, Eric F. Howard, Erwin J. Landon, Tetsuo Takagi
Publikováno v:
Journal of Hypertension. 18:1239-1246
Objective Chronic feeding of a purified synthetic diet induces renin-angiotensin system-dependent moderate high blood pressure in normal Sprague-Dawley rats. The present study was designed to characterize the angiotensin II (Ang II) receptor type 2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b0c5cda36ea6c005c87db0aaa0dfaf
https://doi.org/10.1097/00004872-200018090-00010
https://doi.org/10.1097/00004872-200018090-00010
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 78:548-556
To investigate the possible physiological significance of dietary cardiac glycosides in blood pressure regulation, the blood pressure of normal Sprague Dawley rats raised on a regular diet, which naturally contains large amounts of Na+-pump inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a723a4d2c009a910a1835dfd5b69ae
https://doi.org/10.1139/y00-023
https://doi.org/10.1139/y00-023
Publikováno v:
Journal of Biological Chemistry. 275:13420-13426
Recent studies of beta(2)-adrenergic receptor suggest that agonist-promoted receptor internalization may play an important role in extracellular signal-regulated kinase (ERK) activation by G protein-coupled receptors. In the present study, we explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::244df9d045bd00316237980bcd095d87
https://doi.org/10.1074/jbc.275.18.13420
https://doi.org/10.1074/jbc.275.18.13420
Publikováno v:
Journal of Biological Chemistry. 275:8389-8396
Calcium-sensitive tyrosine kinase Pyk2 has been implicated in the regulation of ion channels, cellular adhesion, and mitogenic and hypertrophic reactions. In this study, we have investigated the regulation of Pyk2 by angiotensin II (Ang II) in pulmon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::586190d549a09544b9e1e09ce92cd0fd
https://doi.org/10.1074/jbc.275.12.8389
https://doi.org/10.1074/jbc.275.12.8389
Publikováno v:
Clinical and Experimental Hypertension. 20:543-550
To identify the origins and structures of mammalian tissue-derived Na+,K+-ATPase inhibitors, we investigated the tissue distribution of inhibitors in rats. Among many tissues tested, urine was found to contain high levels of many inhibitors. The stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095a68369c0fb2aa94a4c41dc1a0c641
https://doi.org/10.3109/10641969809053232
https://doi.org/10.3109/10641969809053232