Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Erwin H. van den Burg"'
Autor:
Chloe Hegoburu, Yan Tang, Ruifang Niu, Supriya Ghosh, Rodrigo Triana Del Rio, Isabel de Araujo Salgado, Marios Abatis, David Alexandre Mota Caseiro, Erwin H. van den Burg, Christophe Grundschober, Ron Stoop
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The presence of a companion can reduce fear, but the neural mechanisms underlying this social buffering of fear are incompletely known. We studied social buffering of fear in male and female, and its encoding in the amygdala of male, auditor
Externí odkaz:
https://doaj.org/article/b58bf69782eb4b4db4ecba5e07e13753
Autor:
Anna K. Schmidtner, Anna Bludau, Magdalena Meyer, Melanie Royer, David A. Slattery, Inga D. Neumann, Julia Winter, Finn Hartmann, Oliver J. Bosch, Benjamin Jurek, Marta Bianchi, Sebastian Peters, Ilona Berger, Simone Stang, Kerstin Kuffner, Stefan O. Reber, Dominik Langgartner, Erwin H. van den Burg
The neuropeptide oxytocin (OXT) has generated considerable interest as potential treatment for psychiatric disorders, including anxiety and autism spectrum disorders. However, the behavioral and molecular consequences associated with chronic OXT trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dccd8fe2d4065e0b300a8f6f8647b1b
Autor:
Benjamin Jurek, David A Slattery, Rodrigue Maloumby, Katharina Hillerer, Sophie Koszinowski, Inga D Neumann, Erwin H van den Burg
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37060 (2012)
The c-Raf - MEK1/2 - ERK1/2 mitogen-activated protein kinase (MAPK) intracellular signalling cascade in neurons plays important roles in the control of a variety of behaviours, including social behaviours and anxiety. These roles partially overlap wi
Externí odkaz:
https://doaj.org/article/797347f995394f75bc2e274512759ea3
Autor:
Erwin H. van den Burg, Chloé Hegoburu
Publikováno v:
Neuropharmacology. 173:108130
Many studies in preclinical animal models have described fear-reducing effects of the neuropeptide oxytocin in the central nucleus of the amygdala. However, recent studies have refined the role of oxytocin in the central amygdala, which may extend to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1ef00e993205f5efced2944693c2df
https://doi.org/10.1016/j.neuropharm.2020.108130
https://doi.org/10.1016/j.neuropharm.2020.108130
Autor:
Inga D. Neumann, Benjamin Jurek, David A. Slattery, Carl-Philipp Meinung, Stefanie Martinetz, Erwin H. van den Burg, David von Schack
Publikováno v:
Biological psychiatry. 85(10)
Background The neuropeptide oxytocin (OXT) mediates its actions, including anxiolysis, via its G protein–coupled OXT receptor. Within the paraventricular nucleus of the hypothalamus (PVN), OXT-induced anxiolysis is mediated, at least in part, via a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe5781a9de1c319918ce4699acdecff
https://pubmed.ncbi.nlm.nih.gov/30826070
https://pubmed.ncbi.nlm.nih.gov/30826070
Autor:
Erwin H. van den Burg, Ron Stoop
Publikováno v:
Cell and tissue research. 375(1)
The central amygdala has a rich repertoire of neuropeptides and neuropeptide receptors. The diverse ways in which they modulate neuronal activity and influence synaptic activity are discussed here mostly in the context of fear and anxiety-related beh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b10af09bdfb018e14187d238b7e305
https://pubmed.ncbi.nlm.nih.gov/29948174
https://pubmed.ncbi.nlm.nih.gov/29948174
Publikováno v:
Psychopharmacology. 236(1)
The extinction of conditioned fear responses entrains the formation of safe new memories to decrease those behavioral responses. The knowledge in neuronal mechanisms of extinction is fundamental in the treatment of anxiety and fear disorders. Interes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a010d75136ded1775b1578e3b776587
https://pubmed.ncbi.nlm.nih.gov/30302511
https://pubmed.ncbi.nlm.nih.gov/30302511
Autor:
Yuichi Hiraoka, Katsuhiko Nishimori, Benjamin Jurek, Erwin H. van den Burg, Ying Liu, Greti Aguilera, Inga D. Neumann, David A. Slattery
Publikováno v:
The Journal of Neuroscience. 35:12248-12260
The major regulator of the neuroendocrine stress response in the brain is corticotropin releasing factor (CRF), whose transcription is controlled by CREB and its cofactors CRTC2/3 (TORC2/3). Phosphorylated CRTCs are sequestered in the cytoplasm, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d571c69981f5cb23fef48b2ac26c54a
https://doi.org/10.1523/jneurosci.1345-14.2015
https://doi.org/10.1523/jneurosci.1345-14.2015
Publikováno v:
Annual Review of Neuroscience
© 2015 by Annual Reviews. All rights reserved. In the present review we discuss how the evolution of oxytocin and vasopressin from a single ancestor peptide after gene duplication has stimulated the development of the vertebrate social brain. Separa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff44d4c2eb4069f8be3907662e147af1
https://doi.org/10.1146/annurev-neuro-071714-033904
https://doi.org/10.1146/annurev-neuro-071714-033904
Autor:
Inga D. Neumann, Erwin H. van den Burg
Publikováno v:
Journal of Molecular Neuroscience. 43:200-208
Neuropeptides of the brain are important neuromodulators, controlling behaviour and physiology. They signal through G protein-coupled receptors (GPCR) that couple to complex intracellular signalling pathways. These signalling networks integrate infor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbae556ef43da2f90abd3d438fcdeeb4
https://doi.org/10.1007/s12031-010-9452-8
https://doi.org/10.1007/s12031-010-9452-8