Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Erwin Garcia"'
Autor:
Erwin Garcia, Irina Shalaurova, Steven P. Matyus, Lita A. Freeman, Edward B. Neufeld, Maureen L. Sampson, Rafael Zubirán, Anna Wolska, Alan T. Remaley, James D. Otvos, Margery A. Connelly
Publikováno v:
Molecules, Vol 29, Iss 3, p 564 (2024)
Lipoprotein X (LP-X) is an abnormal cholesterol-rich lipoprotein particle that accumulates in patients with cholestatic liver disease and familial lecithin–cholesterol acyltransferase deficiency (FLD). Because there are no high-throughput diagnosti
Externí odkaz:
https://doaj.org/article/7b4075c84b5d4606bf457aaea0b6e7e5
Autor:
Waseem Amjad, Irina Shalaurova, Erwin Garcia, Eke G. Gruppen, Robin P. F. Dullaart, Alex M. DePaoli, Z. Gordon Jiang, Michelle Lai, Margery A. Connelly
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13332 (2023)
Nonalcoholic fatty liver disease (NAFLD) is associated with mitochondrial damage. Circulating mitochondrial metabolites may be elevated in NAFLD but their associations with liver damage is not known. This study aimed to assess the association of key
Externí odkaz:
https://doaj.org/article/7de8bd1b42b347c2ad07b715a7df4166
Autor:
Andrea Sitlinger, Michael A. Deal, Erwin Garcia, Margery Connelly, Dana Thompson, Tiffany Stewart, Grace Macdonald, Erik D. Hanson, Megan Neely, Ben Neely, Ashley Artese, J. Brice Weinberg, Danielle Brander, David B. Bartlett
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Many patients with chronic lymphocytic leukemia (CLL) experience physical dysfunction and low overall fitness. It remains unknown what factors drive CLL physical dysfunction. We assessed physical function and metabolic lipoprotein panels in 106 patie
Externí odkaz:
https://doaj.org/article/067d5232fc8a4d92a767d2673f130796
Autor:
Erwin Garcia, Dennis W. Bennett, Margery A. Connelly, Elias J. Jeyarajah, Franklin C. Warf, Irina Shalaurova, Steven P. Matyus, Justyna Wolak-Dinsmore, David N. Oskardmay, Randolph M. Young, Maureen Sampson, Alan T. Remaley, James D. Otvos
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-11 (2020)
Abstract Background Standard lipid panel assays employing chemical/enzymatic methods measure total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C), from which are calculated estimates of low-density lipoprotein
Externí odkaz:
https://doaj.org/article/3c2856fe12cf477db880001f9fbcec69
Autor:
Jose L. Flores-Guerrero, Marco A. Grzegorczyk, Margery A. Connelly, Erwin Garcia, Gerjan Navis, Robin P.F. Dullaart, Stephan J.L. Bakker
Publikováno v:
EBioMedicine, Vol 71, Iss , Pp 103550- (2021)
Background: The potential role of individual plasma biomarkers in the pathogenesis of type 2 diabetes (T2D) has been broadly studied, but the impact of biomarkers interaction remains underexplored. Recently, the Mahalanobis distance (MD) of plasma bi
Externí odkaz:
https://doaj.org/article/b818855217e94ecfb6c63adda47377c2
Autor:
Steven P. Matyus, Justyna Wolak-Dinsmore, Erwin Garcia, Randolph M. Young, Margery A. Connelly
Publikováno v:
Diagnostics, Vol 12, Iss 11, p 2606 (2022)
Urine citrate is often used to identify patients at risk of recurrent nephrolithiasis or kidney stones. A high-throughput assay was developed to measure urine citrate and creatinine on the Vantera® Clinical Analyzer, a nuclear magnetic resonance (NM
Externí odkaz:
https://doaj.org/article/e2993a2a9ed54eaf8cd14d644cf39fb0
Autor:
Amarens van der Vaart, Martine G. E. Knol, Martin H. de Borst, Stephan J. L. Bakker, Margery A. Connelly, Erwin Garcia, Henk J. G. Bilo, Peter R. van Dijk, Robin P. F. Dullaart
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1318 (2022)
Introduction: Fasting plasma ketone bodies (KB) are elevated in individuals with type 2 diabetes (T2D) and could affect glycemic control and disease progression. Prolonged KB exposure may result in adaptive beneficial responses, counteracting glycemi
Externí odkaz:
https://doaj.org/article/fe5da740107841eb8b685e4249c62b67
Publikováno v:
Practical Laboratory Medicine, Vol 25, Iss , Pp e00213- (2021)
Objectives: Despite reports highlighting citrate association with different diseases, serum citrate is scarcely used for diagnosis. Existing methods to quantify citrate are limited by their complexity and practicality of implementation. A simple and
Externí odkaz:
https://doaj.org/article/c81d5d0bcb254335a715d3b06869582f
Autor:
Erwin Garcia, Irina Shalaurova, Steven P. Matyus, Joelle C. Schutten, Stephan J. L. Bakker, Robin P. F. Dullaart, Margery A. Connelly
Publikováno v:
Nutrients, Vol 14, Iss 9, p 1792 (2022)
The aims were to optimize a nuclear magnetic resonance (NMR)-based assay for quantifying ionized or free magnesium and investigate its association with type 2 diabetes (T2D). A high-throughput, ionized magnesium assay was optimized and evaluated. Pla
Externí odkaz:
https://doaj.org/article/b02dd7d2a472413797a01e78972917eb
Autor:
Eline H. van den Berg, Jose L. Flores-Guerrero, Eke G. Gruppen, Erwin Garcia, Margery A. Connelly, Vincent E. de Meijer, Stephan J. L. Bakker, Hans Blokzijl, Robin P. F. Dullaart
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 5, p 1223 (2022)
Detailed information regarding lipoprotein concentrations and subfractions in cirrhotic patients before and after orthotopic liver transplantation (OLT) is lacking. Lipoprotein-Z (LP-Z) is a recently characterised abnormal, hepatotoxic free cholester
Externí odkaz:
https://doaj.org/article/9b39e5b802c24eba83b1e9f131a80804