Výsledky vyhledávání

Isolation and Characterization of Heparin From Tuna Skins

Autor: Elaine C. Bau, Jeanine M. Walenga, Aline Mendes, Debra Hoppensteadt, Carl P. Dietrich, Meredith K. McDonald, Erwin Coyne, Walter Jeske

Publikováno v: Clinical and Applied Thrombosis/Hemostasis. 13:137-145

This study characterized heparin isolated from tuna skins. Glycosaminoglycans were isolated from tuna skin after digestion using anion exchange resin. Heparin was eluted from the resin by sodium chloride gradient and was further fractionated by aceto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b5e355ae9f891625ab7b72fd667dea
https://doi.org/10.1177/1076029606298982

Zobrazit plný text záznamu

Antiplatelet Agents: Current Drugs and Future Trends

Autor: Walter Jeske, Fred Leya, William H. Wehrmacher, Leslie Cho, Sohrab Mobarhan, Erwin Coyne, John F. Moran, Harry L. Messmore

Publikováno v: Hematology/Oncology Clinics of North America. 19:87-117

Antiplatelet drugs in clinical use are discussed in terms of their mechanisms of action and the relevancy of that to the physiology of platelets and the pathophysiology of arterial thrombosis. Current clinical usage is outlined in detail for each dru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1b940678a650b2736449cc2c83997e
https://doi.org/10.1016/j.hoc.2004.09.004

Zobrazit plný text záznamu

Heparin to Pentasaccharide and Beyond: The End Is Not in Sight

Autor: Jawed Fareed, William H. Wehrmacher, Harry L. Messmore, Erwin Coyne

Publikováno v: Seminars in Thrombosis and Hemostasis. 30:81-88

The 87-year history of heparin began in 1916 when a 26-year-old medical student named Jay McLean startled his mentor William Howell, Professor of Physiology at Johns Hopkins University, by proclaiming that he had discovered "antithrombin." This disco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3936163b5f96456f2a11de85e025b36
https://doi.org/10.1055/s-2004-823006

Zobrazit plný text záznamu

Porcine and Ovine Mucosal Heparins and Their Depolymerized Derivatives Are Comparable in Contrast to Their Bovine Equivalents

Autor: Paula Maia, Emmanuele Kumar, Erwin Coyne, Olivia Bouchard, Yimng Yao, Daniel Kahn, Jawed Fareed, Jeanine M. Walenga, Debra Hoppensteadt, Alice Silva de Castro, Walter Jeske, Nil Guler

Publikováno v: Blood. 128:5027-5027

Introduction: The currently used unfractionated heparin (UFH) and low molecular weight heparins (LMWH) are mostly derived from Porcine mucosal tissue. Since the technology to manufacture heparin has advanced and the quality assurance practices are in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::675b3e6ae7a27a1fd273d0407c74f22a
https://doi.org/10.1182/blood.v128.22.5027.5027

Zobrazit plný text záznamu

Resourcing of Heparin and Low Molecular Weight Heparins from Bovine, Ovine, and Porcine Origin. Studies to Demonstrate the Biosimilarities

Autor: Daniel Kahn, Nil Guler, Jeanine M. Walenga, Alice Silva, Erwin Coyne, Walter Jeske, Debra Hoppensteadt, Emmanuel Kumar, Jawed Fareed, Paula Maia

Publikováno v: Blood. 126:4733-4733

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c60e59fe54b89cd2c073609e4d8dc9c
https://doi.org/10.1182/blood.v126.23.4733.4733

Zobrazit plný text záznamu

Generic low molecular weight heparins: a significant dilemma

Autor: Jawed Fareed, Rakesh Wahi, Rodger L. Bick, Erwin Coyne, Omer Iqbal, Shaker A. Mousa, Helena B. Nader

Publikováno v: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 11(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b69cd9d04d17cf1c5c1de7e7cb975e
https://pubmed.ncbi.nlm.nih.gov/16244760

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání