Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Erwann Philippe"'
Autor:
Aurélie Le Lay, Erwann Philippe, Fanny Roth, Ana Rodriguez Sanchez-Archidona, Florence Mehl, Jessica Denom, Rashmi Prasad, Olof Asplund, Ola Hansson, Mark Ibberson, Fabrizio Andreelli, Lyse Santoro, Paul Amouyal, Gilles Amouyal, Christian Brechot, Laure Jamot, Céline Cruciani-Guglielmacci, Christophe Magnan
Publikováno v:
Heliyon, Vol 8, Iss 7, Pp e09944- (2022)
The aim of our study was to test the hypothesis that administration of Regenerating islet-derived protein 3α (Reg3α), a protein described as having protective effects against oxidative stress and anti-inflammatory activity, could participate in the
Externí odkaz:
https://doaj.org/article/39cc50e19eae451892b45ead46bd57b6
Autor:
Aude Barataud, Justine Vily-Petit, Daisy Goncalves, Carine Zitoun, Adeline Duchampt, Erwann Philippe, Amandine Gautier-Stein, Gilles Mithieux
Publikováno v:
Molecular Metabolism, Vol 31, Iss , Pp 14-23 (2020)
Objective: Roux-en-Y gastric surgery (RYGB) promotes a rapid and sustained weight loss and amelioration of glucose control in obese patients. A high number of molecular hypotheses were previously tested using duodenal-jejunal bypass (DJB) performed i
Externí odkaz:
https://doaj.org/article/6ad0d3f0ae064100a71a14d68492d7b2
Autor:
Keizo Kaneko, Maud Soty, Carine Zitoun, Adeline Duchampt, Marine Silva, Erwann Philippe, Amandine Gautier-Stein, Fabienne Rajas, Gilles Mithieux
Publikováno v:
Molecular Metabolism, Vol 16, Iss , Pp 203-212 (2018)
Objective: The respective contributions to endogenous glucose production (EGP) of the liver, kidney and intestine vary during fasting. We previously reported that the deficiency in either hepatic or intestinal gluconeogenesis modulates the repartitio
Externí odkaz:
https://doaj.org/article/24ce25ccbfac4053b1537a92a6860cf0
Autor:
Mélanie Campana, Lara Bellini, Claude Rouch, Latif Rachdi, Nicolas Coant, Noémie Butin, Cécile L. Bandet, Erwann Philippe, Kelly Meneyrol, Nadim Kassis, Julien Dairou, Eric Hajduch, Benoit Colsch, Christophe Magnan, Hervé Le Stunff
Publikováno v:
Molecular Metabolism, Vol 8, Iss , Pp 23-36 (2018)
Objectives: Hypothalamic lipotoxicity has been shown to induce central insulin resistance and dysregulation of glucose homeostasis; nevertheless, elucidation of the regulatory mechanisms remains incomplete. Here, we aimed to determine the role of de
Externí odkaz:
https://doaj.org/article/36162c8527874fe1a2f4d78629f38b0c
Autor:
Valentine S Moullé, Christelle Le Foll, Erwann Philippe, Nadim Kassis, Claude Rouch, Nicolas Marsollier, Linh-Chi Bui, Christophe Guissard, Julien Dairou, Anne Lorsignol, Luc Pénicaud, Barry E Levin, Céline Cruciani-Guglielmacci, Christophe Magnan
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74021 (2013)
Variations in plasma fatty acid (FA) concentrations are detected by FA sensing neurons in specific brain areas such as the hypothalamus. These neurons play a physiological role in the control of food intake and the regulation of hepatic glucose produ
Externí odkaz:
https://doaj.org/article/749e6df341bd4cf786146613e7bb071f
Autor:
Danielle Bailbé, Erwann Philippe, Evgeniy Gorbunov, Sergey Tarasov, Oleg Epstein, Bernard Portha
Publikováno v:
Journal of Diabetes Research, Vol 2013 (2013)
The aim of the present study was to evaluate the potential antidiabetic effects of two-component drug Subetta and its components (release-active dilutions of antibodies to β-subunit insulin receptor (RAD of Abs to β-InsR) and to endothelial nitric
Externí odkaz:
https://doaj.org/article/8af5dbb828e24422b1b06b1f234277f6
Autor:
Aurélie Joly-Amado, Maud Soty, Erwann Philippe, Amelie Lacombe, Julien Castel, Bruno Pillot, Justine Vily-Petit, Carine Zitoun, Gilles Mithieux, Christophe Magnan
Publikováno v:
Journal of Nutrition
Journal of Nutrition, 2022, 152 (8), pp.1862-1871. ⟨10.1093/jn/nxac097⟩
Journal of Nutrition, 2022, 152 (8), pp.1862-1871. ⟨10.1093/jn/nxac097⟩
International audience; ABSTRACT Background The role of hepatoportal glucose sensors is poorly understood in the context of insulin resistance. Objectives We assessed the effects of glucose infusion in the portal vein on insulin tolerance in 2 rat mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62d27790c1030dbb4ec4924f1bfa3f9
https://www.hal.inserm.fr/inserm-03792841
https://www.hal.inserm.fr/inserm-03792841
Ceramide Transporter CERT Is Involved in Muscle Insulin Signaling Defects Under Lipotoxic Conditions
Autor:
Erwann Philippe, Athanassia Sotiropoulos, Hervé Le Stunff, Agnieszka Blachnio-Zabielska, Julien Véret, Paola Giussani, Fabienne Foufelle, Cécile L Bandet, Maxime Poirier, Xavier Le Liepvre, Olivier Bourron, Pascal Ferré, Eric Hajduch, Raphaëlle Ballaire, Jan Górski, Dušan Berkeš, Rana Mahfouz, Mélanie Campana
Publikováno v:
Diabetes
Diabetes, American Diabetes Association, 2018, 67 (7), pp.1258-1271. ⟨10.2337/db17-0901⟩
Diabetes, 2018, 67 (7), pp.1258-1271. ⟨10.2337/db17-0901⟩
Diabetes, American Diabetes Association, 2018, 67 (7), pp.1258-1271. ⟨10.2337/db17-0901⟩
Diabetes, 2018, 67 (7), pp.1258-1271. ⟨10.2337/db17-0901⟩
International audience; One main mechanism of insulin resistance (IR), a key feature of type 2 diabetes, is the accumulation of saturated fatty acids (FAs) in the muscles of obese patients with type 2 diabetes. Understanding the mechanism that underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c98612fe781a2776f3e46af4629e39a
https://hal.archives-ouvertes.fr/hal-02450782
https://hal.archives-ouvertes.fr/hal-02450782
Autor:
Mara Dierssen, Erwann Philippe, Latif Rachdi, Christophe Magnan, Raphael G. P. Denis, Nathalie Janel, H. Le Stunff, Marta Fructuoso
Publikováno v:
Free radical biologymedicine. 118
Autor:
Christophe Magnan, Stéphanie Migrenne Li, Guy A. Rutter, Elisa A. Bellomo, Erwann Philippe, Alejandra Tomas, Pedro Luis Herrera, David J. Hodson, Antonia Solomou, Gargi Meur
Publikováno v:
Journal of Biological Chemistry, Vol. 290, No 35 (2015) pp. 21432-21442
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Background: The role of the type 2 diabetes risk gene SLC30A8, encoding ZnT8, in the control of glucagon secretion is not clearly established. Results: Inactivation of ZnT8 in a subset of α-cells leads to increased glucagon secretion in vivo and in