Ulva lactuca, A Source of Troubles and Potential Riches

Autor: Herminia Dominguez, Erwann P. Loret

Publikováno v: Marine Drugs, Vol 17, Iss 6, p 357 (2019)

Ulva lactuca is a green macro alga involved in devastating green tides observed worldwide. These green tides or blooms are a consequence of human activities. Ulva blooms occur mainly in shallow waters and the decomposition of this alga can produce da

Externí odkaz: https://doaj.org/article/bb038bea418e4c16b2abfce0690128fc

A Low Molecular Weight Protein from the Sea Anemone Anemonia viridis with an Anti-Angiogenic Activity

Autor: Erwann P. Loret, José Luis, Christopher Nuccio, Claude Villard, Pascal Mansuelle, Régine Lebrun, Pierre Henri Villard

Publikováno v: Marine Drugs, Vol 16, Iss 4, p 134 (2018)

Sea anemones are a remarkable source of active principles due to a decentralized venom system. New blood vessel growth or angiogenesis is a very promising target against cancer, but the few available antiangiogenic compounds have limited efficacy. In

Externí odkaz: https://doaj.org/article/f55f88ae0748401d861a667ba78c16a2

Multimodality vaccination against clade C SHIV: Partial protection against mucosal challenges with a heterologous tier 2 virus

Autor: Marjorie Robert-Guroff, Erwann P. Loret, James G. Else, Sandra J. Lee, Robert A. Rasmussen, Donald N. Forthal, Shannon Stock, Francois Villinger, Mingkui Zhou, Barbara C. Bachler, Victoria R. Polonis, Ruth M. Ruprecht, Welkin E. Johnson, Diego A. Vargas-Inchaustegui, Egidio Brocca Cofano, Girish Hemashettar, Siddappa N. Byrareddy, Shiu Lok Hu, Samir K. Lakhashe

Publikováno v: Vaccine. 32:6527-6536

We sought to test whether vaccine-induced immune responses could protect rhesus macaques (RMs) against upfront heterologous challenges with an R5 simian-human immunodeficiency virus, SHIV-2873Nip. This SHIV strain exhibits many properties of transmit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73134375697787001f6e84c5988a3919
https://doi.org/10.1016/j.vaccine.2014.08.065

Two purified and characterized phospholipases A2 from Cerastes cerastes venom, that inhibit cancerous cell adhesion and migration

Autor: Erwann P. Loret, Olfa Kallech-Ziri, Naziha Marrakchi, Amine Bazaa, Sofiane Bezzine, Najet Srairi-Abid, Aida Karray, José Luis, Raoudha Zouari-Kessentini, Mohamed El Ayeb

Publikováno v: Toxicon
Toxicon, Elsevier, 2009, 53 (4), pp.444-53. ⟨10.1016/j.toxicon.2009.01.003⟩

International audience; Two non-toxic PLA2s were purified to homogeneity from Cerastes cerastes Tunisian snake venom. The purification process employed gel filtration on Sephadex G-75 followed by C18 reverse phase high-pressure liquid chromatography.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1316e6552d2676bd807c7b7dddcd5f46
https://doi.org/10.1016/j.toxicon.2009.01.003

Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells

Autor: Françoise Sanchez, Bruno Beaumelle, Solène Debaisieux, Clément Mettling, Yea-Lih Lin, Fabienne Rayne, Anne Bonhoure, Laurence Briant, Nathalie Chazal, Hocine Yezid, Erwann P. Loret, Christian Roy, Martine Pugnière, Stefan T. Arold, Karidia Konate

Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2010, 29 (8), pp.1348-1362. ⟨10.1038/emboj.2010.32⟩
EMBO Journal, 2010, 29 (8), pp.1348-1362. ⟨10.1038/emboj.2010.32⟩

International audience; Human immunodeficiency virus type 1 (HIV-1) transcription relies on its transactivating Tat protein. Although devoid of a signal sequence, Tat is released by infected cells and secreted Tat can affect uninfected cells, thereby

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4354dd2a3ae446c007eff4335d1dc9d
https://hal.archives-ouvertes.fr/hal-02147182/document