Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ervice, Pouokam"'
Publikováno v:
Royal Society Open Science, Vol 9, Iss 10 (2022)
Gold nanoparticles have a high potential to be a treatment of diseases by their specific drug delivery properties and multivalent receptor stimulation. For the present project, spherical gold nanoparticles were synthesized and functionalized with the
Externí odkaz:
https://doaj.org/article/0098416efe4040608ccbb7bdf62538f0
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The pharmacological properties of nitroxyl (HNO) donors in the gastrointestinal tract are unknown. We investigated the properties of this molecule in the regulation of gastrointestinal contractility focusing on its possible interaction with other gas
Externí odkaz:
https://doaj.org/article/1fbb4145db124963a11c6aecb10caff1
Multivalent stimulation of β1-, but not β2-receptors by adrenaline functionalised gold nanoparticles
Autor:
Annabelle Mattern, Rebecca Claßen, Annemarie Wolf, Ervice Pouokam, Klaus-Dieter Schlüter, Mathias S. Wickleder, Martin Diener
Publikováno v:
Nanoscale Advances. 4:3182-3193
Adrenaline functionalised gold nanoparticles had no influence on respiratory smooth muscle cells which are regulated by β2-receptors, while the stimulation of β1-receptors led to an increased contractility of cardiomyocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::530d2a48d8f4b5f6a5e9a3ce7b3d197c
https://doi.org/10.1039/d2na00171c
https://doi.org/10.1039/d2na00171c
Publikováno v:
Journal of Basic and Clinical Physiology and Pharmacology.
Objectives Reactive oxygen and nitrogen species may be produced during inflammation leading to the formation of NO, H2S or HNO. Enzymes such as iNOS, CSE and CBS might also be responsible for polysulfide production. Since these signalling molecules m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93b399c8950899eb9c480a1112e1f029
https://doi.org/10.1515/jbcpp-2021-0181
https://doi.org/10.1515/jbcpp-2021-0181
Publikováno v:
Journal of basic and clinical physiology and pharmacologyReferences.
Reactive oxygen and nitrogen species may be produced during inflammation leading to the formation of NO, HOrgan bath measurements with strips obtained from rat proximal colon were performed using the polysulfide NaAll four molecules, concentration-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::001f109f2b1d2060507637568d4fb4ce
https://pubmed.ncbi.nlm.nih.gov/34624185
https://pubmed.ncbi.nlm.nih.gov/34624185
Autor:
Martin Diener, O. S. Ilyaskina, Moritz Bünemann, F. Machka, Ervice Pouokam, Mathias S. Wickleder, A. Mattern
Publikováno v:
Organic & Biomolecular Chemistry. 16:6680-6687
Gold nanoparticles (NP) with a functionalized ligand shell offer the possibility to potentiate the action of agonists at the receptor site by multivalency. In order to find out whether this can be realized for the pharmacologically important class of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f869155de6454e7fc90f316ebb78ad7
https://doi.org/10.1039/c8ob01686k
https://doi.org/10.1039/c8ob01686k
Autor:
Martin Diener, Ervice Pouokam
Publikováno v:
Pflugers Archiv : European journal of physiology. 471(7)
Ion-transport properties of the epithelium of the cecum, the biggest fermental chamber in non-ruminant species, are largely unknown. Recently, in Ussing chamber experiments, segmental differences in basal short-circuit current (Isc) in rat corpus cec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095db6ef64a40d9ffc872669a6bbf2b4
https://pubmed.ncbi.nlm.nih.gov/31093757
https://pubmed.ncbi.nlm.nih.gov/31093757
Publikováno v:
The Journal of Membrane Biology. 246:271-285
In nonexcitable cells, store-operated Ca(2+) entry is the most important pathway for influx of extracellular Ca(2+) serving as a second messenger in the cytoplasm. The present study investigated the expression, localization and polar distribution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbdc3ebfbf142a35e196edaca5d4485
https://doi.org/10.1007/s00232-013-9528-9
https://doi.org/10.1007/s00232-013-9528-9
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 465:865-877
ATP-sensitive K+ (KATP) channels couple the metabolic state of a cell to its electrical activity. They consist of a hetero-octameric complex with pore-forming Kir6.x (Kir6.1, Kir6.2) and regulatory sulfonylurea receptor (SUR) subunits. Functional dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339d59c3e6bdf0a13b69e7ae96dffa87
https://doi.org/10.1007/s00424-012-1207-7
https://doi.org/10.1007/s00424-012-1207-7
Autor:
Sara Hölzel, Pascal Hille, Mikhail V. Zyuzin, Martin Eickhoff, Martin Diener, Wolfgang J. Parak, Ervice Pouokam, Jan Müßener, Jens Wallys
Publikováno v:
Advanced Functional Materials. 28:1802503
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddcc33eda64736187a683d98513c2c51
https://doi.org/10.1002/adfm.201802503
https://doi.org/10.1002/adfm.201802503