Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Erufosine"'
Autor:
Stefan Kassumeh, Sebastian Arrow, André Kafka, Nikolaus Luft, Siegfried G. Priglinger, Armin Wolf, Kirsten Eibl-Lindner, Christian M. Wertheimer
Publikováno v:
International Journal of Ophthalmology, Vol 15, Iss 10, Pp 1569-1576 (2022)
AIM: To screen five potential pharmacological substances specifically targeting EGF-R, MAPK, mTOR, or PI3K for their antiproliferative effects, possible impact on cell viability, as well as cell death rates on three different uveal melanoma metastasi
Externí odkaz:
https://doaj.org/article/e1a9f9d7a74944938c375ca640b8a1bf
Publikováno v:
Bulgarian Journal of Veterinary Medicine, Vol 24, Iss 3, Pp 442-449 (2021)
Cancer has become one of the most significant health challenges for both human and veterinary medicine. The present study examined the antineoplastic and antimetastatic activity of the novel membrane-targeting anticancer agent erufosine. The antitumo
Externí odkaz:
https://doaj.org/article/4fcdcd458d4a41f5a1bfa28ee4fe3611
Autor:
Antonios G. X. Trochopoulos, Yana Ilieva, Alexander D. Kroumov, Lyudmila L. Dimitrova, Ivanka Pencheva-El Tibi, Stanislav Philipov, Martin R. Berger, Hristo M. Najdenski, Krassimira Yoncheva, Spiro M. Konstantinov, Maya M. Zaharieva
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2688 (2022)
Cutaneous T-cell lymphoma (CTCL) is a rare form of cancer with local as well as systemic manifestations. Concomitant bacterial infections increase morbidity and mortality rates due to impaired skin barrier and immune deficiency. In the current study,
Externí odkaz:
https://doaj.org/article/ebbfec9adf86471fbb1dec78e8419400
Dual Gene Delivery Reagents From Antiproliferative Alkylphospholipids for Combined Antitumor Therapy
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Alkylphospholipids (APLs) have elicited great interest as antitumor agents due to their unique mode of action on cell membranes. However, their clinical applications have been limited so far by high hemolytic activity. Recently, cationic prodrugs of
Externí odkaz:
https://doaj.org/article/83257af621d245de962c99a988babe5f
Autor:
Maya Margaritova Zaharieva, Alexander Dimitrov Kroumov, Lyudmila Dimitrova, Iva Tsvetkova, Antonios Trochopoulos, Spiro Mihaylov Konstantinov, Martin Reinhold Berger, Milena Momchilova, Krassimira Yoncheva, Hristo Miladinov Najdenski
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 38-53 (2019)
In the light of the emerging bacterial resistance to broad-spectrum antibiotics, the search for new antibacterial therapeutics and drug combinations is one of the most challenging topics nowadays. In the present study, we investigated for the first t
Externí odkaz:
https://doaj.org/article/b1038d7210de48bbaa6fedf50dc81862
Akademický článek
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Autor:
Hüseyin Abdik
Publikováno v:
Molecular Biology Reports. 49:2963-2971
Background Lung cancer (LC) is the most common types of cancer worldwide and is marked by high mortality rate. LC is classified into two major types due to their molecular and histological properties; non-small cell lung cancer (NSCLC) A549 and small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6395c0d2a73bf5843de4d432ca100157
https://doi.org/10.1007/s11033-022-07117-6
https://doi.org/10.1007/s11033-022-07117-6
Autor:
Ferda Kaleağasıoğlu, Fikrettin Şahin, Duygu Turan, Martin R. Berger, Hüseyin Abdik, Ezgi Avşar Abdik
Publikováno v:
Molecular Biology Reports. 48:7755-7765
Background Cancer cell survival depends on the cross-regulation between apoptosis and autophagy which share common signaling pathways including PI3K/Akt/mTOR and Bcl-2. The aim of this study was to elucidate the modulation patterns between apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198611005274f3b3ea86d06d8002f227
https://doi.org/10.1007/s11033-021-06786-z
https://doi.org/10.1007/s11033-021-06786-z
Autor:
Bueno, Luciana de Moura
O câncer corresponde a um conjunto de doenças que vem aumentando sua incidência durantes os anos e atualmente é considerado um problema mundial. Os tratamentos tradicionais em sua grande maioria agem no maquinário genético e causam citotoxicida
Akademický článek
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