Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation.

Autor: Chan AS; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Jonas AB; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Qiu X; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Ottoson NR; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Walsh RM; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Gorden KB; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Harrison B; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Maimonis PJ; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Leonardo SM; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Ertelt KE; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Danielson ME; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Michel KS; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Nelson M; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Graff JR; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Patchen ML; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America., Bose N; Biothera Pharmaceuticals Inc., Eagan, Minnesota, United States of America.

Publikováno v: PloS one [PLoS One] 2016 Nov 03; Vol. 11 (11), pp. e0165909. Date of Electronic Publication: 2016 Nov 03 (Print Publication: 2016).

Pleurotus ostreatus extract Enhances the Phagocytic Actions of Neutrophils against Streptococcus pneumoniae.

Autor: Oli, Angus Nnamdi¹ a.n.oli@live.com, Emeruwa, Akunna Perpetual¹, Ekwunife, Obinna Ikechukwu², Okoye, Ebele Linda³, Anyaoku, Chinekwu S.⁴, Ibeanu, Gordon C.⁵, Obi, Ejeatuluchukwu⁶, Ihekwereme, Chibueze Peter⁷, Obaji, Monday¹

Publikováno v: Annals of Medical & Health Sciences Research. Mar/Apr2019, Vol. 9 Issue 2, p499-508. 10p.

Abstract OT1-01-04: A phase 2, open-label study of imprime PGG (Imprime), a novel beta glucan, with pembrolizumab (Pembro) in chemotherapy-resistant metastatic triple negative breast cancer (TNBC)

Autor: Alison Stopeck, Paulette Mattson, Michael Chisamore, Richard D. Huhn, B Ma, Mark T. Uhlik, Jeremy R. Graff, R Prathikanti, Nandita Bose, Michele Gargano, Katie Ertelt, Steven J. O'Day, Jamie Lowe, Nadine Ottoson

Publikováno v: Cancer Research. 78:OT1-01

By blocking the interaction of PD-L1 with PD-1, immune checkpoint inhibitors (CPI) can unleash specific, anti-cancer killing function of activated cytotoxic T cells in patients (pts) for whom there is evidence of an ongoing anti-cancer immune respons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a676258bb97b62a37b60523f9eebe823
https://doi.org/10.1158/1538-7445.sabcs17-ot1-01-04

Fc Mediated Activity of Antibodies : Structural and Functional Diversity

Autor: Jeffrey V. Ravetch, Falk Nimmerjahn

This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and e