Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ersilia Barin"'
Autor:
Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Eren L. Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y. Q. Han, Aspen J. Pierson, Michael Xiao, Xuejing Yang, Lindsey M. Kuehm, Yuning Hong, Diu T. T. Nguyen, Gabriela Chiosis, Alex Kentsis, Christina Leslie, Ly P. Vu, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Tissue homeostasis is maintained after stress by engaging and activating the hematopoietic stem and progenitor compartments in the blood. Hematopoietic stem cells (HSCs) are essential for long-term repopulation after secondary transplantatio
Externí odkaz:
https://doaj.org/article/a849e3d3deda463181789ab17c11b2cd
Autor:
Camile C. Fontelles, Raquel Santana da Cruz, Alexandra K. Gonsiewski, Ersilia Barin, Volkan Tekmen, Lu Jin, M. Idalia Cruz, Olivier Loudig, Anni Warri, Sonia de Assis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract We previously showed that environmentally-induced epigenetic inheritance of cancer occurs in rodent models. For instance, we reported that paternal consumption of an obesity-inducing diet (OID) increased breast cancer susceptibility in the o
Externí odkaz:
https://doaj.org/article/9320a5d49cd74380a28f30c854e99566
Autor:
Diu T. T. Nguyen, Yuheng Lu, Eren L. Chu, Xuejing Yang, Sun-Mi Park, Zi-Ning Choo, Christopher R. Chin, Camila Prieto, Alexandra Schurer, Ersilia Barin, Angela M. Savino, Saroj Gourkanti, Payal Patel, Ly P. Vu, Christina S. Leslie, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract The cell-context dependency for RNA binding proteins (RBPs) mediated control of stem cell fate remains to be defined. Here we adapt the HyperTRIBE method using an RBP fused to a Drosophila RNA editing enzyme (ADAR) to globally map the mRNA t
Externí odkaz:
https://doaj.org/article/57d9dd401d274463904c8c3f4b95b1ec
Autor:
Coraline Mlynarczyk, Matt Teater, Juhee Pae, Christopher R. Chin, Ling Wang, Theinmozhi Arulraj, Darko Barisic, Antonin Papin, Kenneth B. Hoehn, Ekaterina Kots, Jonatan Ersching, Arnab Bandyopadhyay, Ersilia Barin, Hui Xian Poh, Chiara M. Evans, Amy Chadburn, Zhengming Chen, Hao Shen, Hannah M. Isles, Benedikt Pelzer, Ioanna Tsialta, Ashley S. Doane, Huimin Geng, Muhammad Hassan Rehman, Jonah Melnick, Wyatt Morgan, Diu T. T. Nguyen, Olivier Elemento, Michael G. Kharas, Samie R. Jaffrey, David W. Scott, George Khelashvili, Michael Meyer-Hermann, Gabriel D. Victora, Ari Melnick
Publikováno v:
Science. 379
Multicellular life requires altruistic cooperation between cells. The adaptive immune system is a notable exception, wherein germinal center B cells compete vigorously for limiting positive selection signals. Studying primary human lymphomas and deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89af1728240b964263f280725c1cf48f
https://doi.org/10.1126/science.abj7412
https://doi.org/10.1126/science.abj7412
Autor:
Coraline Mlynarczyk, Matt Teater, Juhee Pae, Ling Wang, Jonatan Ersching, Antonin Papin, Darko Barisic, Ersilia Barin, Kenneth B. Hoehn, Zhengming Chen, Diu T. T. Nguyen, Chiara Evans, Ashley S. Doane, Michael G. Kharas, David W. Scott, Gabriel Victora, Ari Melnick
Publikováno v:
Blood Cancer Discovery. 3:A24-A24
BTG1 somatic mutations are exclusively found in mature B cell malignancies, ~12% diffuse large B cell lymphoma (DLBCL) and are particularly enriched in the MCD/cluster 5 subtype of ABC-DLBCL, characterized by extranodal dissemination and poor clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::580db9782bf93f5bc7969022f1e329e4
https://doi.org/10.1158/2643-3249.lymphoma22-a24
https://doi.org/10.1158/2643-3249.lymphoma22-a24
Autor:
Ersilia Barin, Alexandra K. Gonsiewski, Anni Wärri, Sonia de Assis, Camile Castilho Fontelles, Olivier Loudig, Raquel Santana da Cruz, Volkan Tekmen, M. Idalia Cruz, Lu Jin
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
We previously showed that environmentally-induced epigenetic inheritance of cancer occurs in rodent models. For instance, we reported that paternal consumption of an obesity-inducing diet (OID) increased breast cancer susceptibility in the offspring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f32349b4068ffe4c7f878824e40e93e
https://doi.org/10.1038/s41598-021-86548-w
https://doi.org/10.1038/s41598-021-86548-w
Autor:
Meera Dhodapkar, Katerina Hoskova, James Taggart, Thomas M. Rohwetter, Saroj Gourkanti, Angela M. Savino, Ulrich Steidl, Timothy Chou, Alexendar R. Perez, Arthur Chow, Raul Rabadan, Alexandra Schurer, Justin C. Wheat, Trevor S. Barlowe, Michael G. Kharas, Christina S. Leslie, Zhaoqi Liu, Anthony Velleca, Ersilia Barin, Camila Prieto, Ly P. Vu, Diu T.T. Nguyen
Publikováno v:
Nature cancer
RNA-binding proteins (RBPs) are key arbiters of post-transcriptional regulation and are found to be dysregulated in hematological malignancies. Here we identify the RBP RNA-binding motif protein, X-linked (RBMX; also known as hnRNPG), and its retroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d415274335668daddaa342161bbbd3fe
http://hdl.handle.net/10281/391390
http://hdl.handle.net/10281/391390
Autor:
Diu Nguyen, Camila Prieto, Zhaoqi Liu, Justin Wheat, Alexander Perez, Saroj Gourkanti, Timothy Chou, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Arthur Chow, James Taggart, Angela Savino, Katerina Hoskova, Meera Dhodapkar, Alexandra Schurer, trevor Barlowe, Christina Leslie, Ly Vu, Ulrich Steidl, Raul Rabandan, Michael Kharas
Publikováno v:
Experimental Hematology. 100:S30-S31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe3f44dd20545ffc863cb48b71f0951e
https://doi.org/10.1016/j.exphem.2021.12.372
https://doi.org/10.1016/j.exphem.2021.12.372
Autor:
Ersilia Barin, Diu Tt. Nguyen, Karen L. Chu, Anthony Velleca, Dinshaw J. Patel, Thomas M. Rohwetter, Samie R. Jaffrey, Brian F. Pickering, Michael G. Kharas, Hanzhi Luo, Xuejing Yang, Shanlan Mo, Yuanming Cheng, Angela M. Savino, Wei Xie
Publikováno v:
Cancer Cell
N(6)-methyladenosine (m(6)A) on mRNAs mediates different biological processes and its dysregulation contributes to tumorigenesis. How m(6)A dictates its diverse molecular and cellular effects in leukemias remains unknown. We found that YTHDC1 is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bd5141c70092b5481649d6ec888bb4
https://pubmed.ncbi.nlm.nih.gov/34079105
https://pubmed.ncbi.nlm.nih.gov/34079105
Autor:
Olivier Loudig, Anni Wärri, M. Idalia Cruz, Volkan Tekmen, Alexandra K. Gonsiewski, Ersilia Barin, Raquel Santana da Cruz, Lu Jin, Sonia de Assis, Camile Castilho Fontelles
BackgroundWhile genetics explains some familial breast cancer cases, we showed that environmentally-induced epigenetic inheritance of breast cancer can also occur in rodent models. We previously reported that paternal consumption of a high-fat diet a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c91bc00565e9a6e22dffaba8a8d8c1d
https://doi.org/10.1101/2020.06.05.136234
https://doi.org/10.1101/2020.06.05.136234