Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system

Autor: Yablokov, E.O. ^*, Sushko, T.A., Kaluzhskiy, L.A., Kavaleuski, A.A., Mezentsev, Y.V., Ershov, P.V., Gilep, A.A., Ivanov, А.S., Strushkevich, N.V.

Publikováno v: In Journal of Steroid Biochemistry and Molecular Biology April 2021 208

Biosensor selection of small compounds, modulating a complex formation between cytochrome P450s and NADPH-dependent P450 oxidoreductase

Autor: Ershov, P.V., Yablokov, E.O., Mezentsev, Y.V., Kaluzhskiy, L.A., Luschik, A.Ya., Tumilovich, A.M., Karputs, A.Yu., Gilep, A.A., Ivanov, А.S.

Publikováno v: Biomedical Chemistry: Research and Methods

The study of the effect of low-molecular-weight compounds (substrates, endogenous metabolites, drugs and xenobiotics) on the kinetic and equilibrium parameters of functionally significant binary protein-protein interactions (PPIs) is of both fundamen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=issn26187531::2cc5a3ddcf77ff566be1faa9ffd34956
http://www.bmc-rm.org/index.php/bmcrm/article/view/134

SPR—Based study of affinity of cytochrome P450s / redox partners interactions modulated by steroidal substrates

Autor: Ershov, P.V., Yablokov, Е.O., Florinskaya, A.V., Mezentsev, Yu.V., Kaluzhskiy, L.А., Tumilovich, A.M., Gilep, А.А., Usanov, S.A., Ivanov, А.S.

Publikováno v: In Journal of Steroid Biochemistry and Molecular Biology March 2019 187:124-129

Signal Enhancement of SPR Biosensor Detection by Using of Gold Nanoparticles for Human beta-2-Microglobulin as a Model Protein Biomarker

Autor: Mezentsev, Yu.V., Gnedenko, O.V., Ershov, P.V., Ivanov, A.S.

Publikováno v: Biomedical Chemistry: Research and Methods; Vol. 1 No. 4 (2018); e00053
Biomedical Chemistry: Research and Methods; Том 1 № 4 (2018); e00053
Biomedical Chemistry: Research and Methods

The highly sensitive method of surface plasmon resonance (SPR) detection of low concentrations of target proteins based on the biosensor signal enhancement by using gold nanoparticles (similar to “sandwich” assay type) is described. The commercia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=issn26187531::ad65c9abb899071cf53f5460d777d554
http://www.bmc-rm.org/index.php/bmcrm/article/view/53

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