Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Error-prone DNA repair"'
Autor:
Yu Kefei
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 54, Pp 759-766 (2022)
Activation-induced cytidine deaminase (AID) initiates somatic hypermutation of immunoglobulin (Ig) gene variable regions and class switch recombination (CSR) of Ig heavy chain constant regions. Two decades of intensive research has greatly expanded o
Externí odkaz:
https://doaj.org/article/67b9c770c0d74f4681de5548e54d1c8d
Autor:
Benjamin B. Morris, Nolan A. Wages, Patrick A. Grant, P. Todd Stukenberg, Ryan D. Gentzler, Richard D. Hall, Wallace L. Akerley, Thomas K. Varghese, Susanne M. Arnold, Terence M. Williams, Vincenzo Coppola, David R. Jones, David T. Auble, Marty W. Mayo
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
It has long been recognized that defects in cell cycle checkpoint and DNA repair pathways give rise to genomic instability, tumor heterogeneity, and metastasis. Despite this knowledge, the transcription factor-mediated gene expression programs that e
Externí odkaz:
https://doaj.org/article/1a759e60bfaf402dba58cabda12ab76f
Publikováno v:
Heliyon, Vol 6, Iss 2, Pp e03258- (2020)
The mechanism of (CAG)n repeat generation, and related expandable repeat diseases in non-dividing cells, is currently understood in terms of a DNA template-based DNA repair synthesis process involving hairpin stabilized slippage, local error-prone re
Externí odkaz:
https://doaj.org/article/d2f6f24c3a8d44739e8fcb2e63f40a89
Akademický článek
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Autor:
Nicole Bernadette Averbeck, Jana eTopsch, Michael eScholz, Wilma eKraft-Weyrather, Marco eDurante, Gisela eTaucher-Scholz
Publikováno v:
Frontiers in Oncology, Vol 6 (2016)
Radiotherapy of solid tumors with charged particles holds several advantages in comparison to photon therapy; among them conformal dose distribution in the tumor, improved sparing of tumor-surrounding healthy tissue, and an increased relative biologi
Externí odkaz:
https://doaj.org/article/e8bfaaca61274b52b135a644447c159d
Autor:
Daniele Caracciolo, Caterina Riillo, Maria Teresa Di Martino, Mariamena Arbitrio, Pierosandro Tagliaferri, Pierfrancesco Tassone
Publikováno v:
International journal of cancer
(2020). doi:10.1002/ijc.33038
info:cnr-pdr/source/autori:Caracciolo Daniele; Riillo Caterina; Arbitrio Mariamena; Di Martino Maria Teresa; Tagliaferri Pierosandro; Tassone Pierfrancesco;/titolo:Error-prone DNA repair pathways as determinants of immunotherapy activity: an emerging scenario for cancer treatment/doi:10.1002%2Fijc.33038/rivista:International journal of cancer (Print)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
(2020). doi:10.1002/ijc.33038
info:cnr-pdr/source/autori:Caracciolo Daniele; Riillo Caterina; Arbitrio Mariamena; Di Martino Maria Teresa; Tagliaferri Pierosandro; Tassone Pierfrancesco;/titolo:Error-prone DNA repair pathways as determinants of immunotherapy activity: an emerging scenario for cancer treatment/doi:10.1002%2Fijc.33038/rivista:International journal of cancer (Print)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
Defects in DNA repair machinery play a critical role in the pathogenesis and progression of human cancer. When they occur, the tumor cells activate error-prone mechanisms which lead to genomic instability and high mutation rate. These defects represe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866142b0a0e059f81407538caf9f68a4
https://doi.org/10.1002/ijc.33038
https://doi.org/10.1002/ijc.33038
Autor:
Boris eGole, Lisa eWiesmüller
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 3 (2015)
Despite manifold efforts to achieve reduced-intensity and -toxicity regimens, secondary leukemia has remained the most severe side effect of chemotherapeutic cancer treatment. Rearrangements involving a short telomeric
Externí odkaz:
https://doaj.org/article/ea832875bebf440e8d8299024f2be79f
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1977 Mar 01. 74(3), 1152-1156.
Externí odkaz:
https://www.jstor.org/stable/66360
Autor:
Laval, F.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1980 May 01. 77(5), 2702-2705.
Externí odkaz:
https://www.jstor.org/stable/8761
Autor:
Daniele Caracciolo, Pierfrancesco Tassone, Caterina Riillo, Pierosandro Tagliaferri, Maria Teresa Di Martino
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1392, p 1392 (2021)
Cancers, Vol 13, Iss 1392, p 1392 (2021)
Simple Summary Cancer onset and progression lead to a high rate of DNA damage, due to replicative and metabolic stress. To survive in this dangerous condition, cancer cells switch the DNA repair machinery from faithful systems to error-prone pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b1307877a39cbd8e7472c064ce5fb7
http://europepmc.org/articles/PMC8003480
http://europepmc.org/articles/PMC8003480