Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Errol P Prens"'
Autor:
William R Swindell, Andrew Johnston, Steve Carbajal, Gangwen Han, Christian Wohn, Jun Lu, Xianying Xing, Rajan P Nair, John J Voorhees, James T Elder, Xiao-Jing Wang, Shigetoshi Sano, Errol P Prens, John DiGiovanni, Mark R Pittelkow, Nicole L Ward, Johann E Gudjonsson
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18266 (2011)
Development of a suitable mouse model would facilitate the investigation of pathomechanisms underlying human psoriasis and would also assist in development of therapeutic treatments. However, while many psoriasis mouse models have been proposed, no s
Externí odkaz:
https://doaj.org/article/457db3053e4b4e1fb3f6cbd23127336d
Autor:
Emoke Rácz, Dorota Kurek, Marius Kant, Ewout M Baerveldt, Edwin Florencia, Sabine Mourits, Dick de Ridder, Jon D Laman, Leslie van der Fits, Errol P Prens
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19806 (2011)
Psoriasis is characterized by hyperproliferation of keratinocytes and by infiltration of activated Th1 and Th17 cells in the (epi)dermis. By expression microarray, we previously found the GATA3 transcription factor significantly downregulated in lesi
Externí odkaz:
https://doaj.org/article/29378433bed34f2687c5267b85d2c84f
Autor:
Alexa B. Kimball, Errol P. Prens, Thierry Passeron, Emanual Maverakis, Irina Turchin, Stefan Beeck, Leonidas Drogaris, Ziqian Geng, Tianyu Zhan, Izabella Messina, Falk G. Bechara
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 5, Pp 1099-1111 (2023)
Abstract Introduction Hidradenitis suppurativa (HS) is a chronic, immune-mediated skin condition characterized by inflammatory lesions that can cause pain, impaired physical activity, and reduced quality of life. This study evaluated the efficacy and
Externí odkaz:
https://doaj.org/article/e2a729e34e50461897894ec721f0c23a
Autor:
Salma Assil, Thomas P. Buters, Pieter W. Hameeteman, Charlie Hallard, Nicoline Treijtel, Tessa Niemeyer – Van der Kolk, Marieke L. de Kam, Edwin F. I. I. I. Florencia, Errol P. Prens, Martijn B. A. van Doorn, Robert Rissmann, Naomi B. Klarenbeek, Manon A. A. Jansen, Matthijs Moerland
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Imiquimod (IMQ) is a topical agent that induces local inflammation via the Toll-like receptor 7 pathway. Recently, an IMQ-driven skin inflammation model was developed in healthy volunteers for proof-of-pharmacology trials. The aim of this study was t
Externí odkaz:
https://doaj.org/article/f03a8555dda44e0c8f9b4a37d47243ce
Autor:
Pim Aarts, Johanna C. van Huijstee, Aviël Ragamin, Joanne L. Reeves, Catherine van Montfrans, Hessel H. van der Zee, Errol P. Prens
Publikováno v:
Dermatology, 239(1), 99-108. Karger
Background: After excision surgery in patients with hidradenitis suppurativa (HS), wounds are usually left open for secondary intention healing. To evaluate wound healing, reliable wound measurement is important. However, digital wound measurement to
Autor:
Koen Dudink, Klasiena Bouwman, Yanqing Chen, Samuel E DePrimo, Ernesto J Munoz-Elias, Pim Aarts, Renske Schappin, Edwin F Florencia, Bennie van Heeswijk, Lisette M Prens, Hessel H van der Zee, Errol P Prens, Kelsey R van Straalen, Barbara Horváth
Publikováno v:
The British journal of dermatology, 188(5), 601-609. Wiley-Blackwell Publishing Ltd
Background The effectiveness of available biologics for the treatment of hidradenitis suppurativa (HS) is limited. Additional therapeutic options are needed. Objectives To investigate the efficacy and mode of action of guselkumab [an anti-interleukin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4457f6eced82e3dbd65f4c82173954
https://pure.eur.nl/en/publications/b84d9b3c-e402-4832-8c4a-fdc9e1f2d91c
https://pure.eur.nl/en/publications/b84d9b3c-e402-4832-8c4a-fdc9e1f2d91c
Autor:
Pim Aarts, Johanna C. van Huijstee, Hessel H. van der Zee, Martijn B.A. van Doorn, Kelsey R. van Straalen, Errol P. Prens
Publikováno v:
Journal of the American Academy of Dermatology. Mosby Inc.
Background: Adalimumab, the only biologic registered for hidradenitis suppurativa, shows clinical response in up to 60% of patients, leaving many patients in need for other treatment options such as surgery. Objective: To compare the clinical effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa3748b5f46c5d74547da2585ed87a3
https://pure.eur.nl/en/publications/4d474663-6a7c-4e52-bfd1-81b2039c8a90
https://pure.eur.nl/en/publications/4d474663-6a7c-4e52-bfd1-81b2039c8a90
Publikováno v:
Dermatology.
Background: Antibiotic resistance is a major concern, especially in HS. However, antibiotics form a cornerstone in its treatment. Topical clindamycin is known to cause bacterial resistance, but is still advised as monotherapy for the treatment of mil
Autor:
Wouter ten Voorde, Mahdi Saghari, Jiry Boltjes, Marieke L. de Kam, Ahnjili Zhuparris, Gary Feiss, Thomas P. Buters, Errol P. Prens, Jeffrey Damman, Tessa Niemeyer‐van der Kolk, Matthijs Moerland, Jacobus Burggraaf, Martijn B. A. van Doorn, Robert Rissmann
Publikováno v:
Experimental Dermatology. Wiley-Blackwell Publishing Ltd
Experimental Dermatology
Experimental Dermatology
Development of pharmacological interventions for wound treatment is challenging due to both poorly understood wound healing mechanisms and heterogeneous patient populations. A standardized and well-characterized wound healing model in healthy volunte
Autor:
Astrid M. van Huizen, Gayle E. van der Kraaij, Celine I. Busard, Wouter Ouwerkerk, Juul M. P. A. van den Reek, Stef P. Menting, Errol P. Prens, Theo Rispens, Annick de Vries, Elke M. G. J. de Jong, Jo Lambert, Martijn B. A. van Doorn, Phyllis I. Spuls
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. Wiley-Blackwell
Background: Anti-drug antibodies (ADA) are formed in patients treated with adalimumab (ADL). This might increase clearance of ADL, potentially causing a (secondary) non-response. Combination therapy of ADL and methotrexate (MTX) reduces ADA levels an